Tài liệu Báo cáo khoa học: Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase organizer 1 doc

... (AF532985), Noxo1a (AY255768 and AF532983), and Noxo1d (AY1 913 59). On the basis of the sequence of splice variants, we synthesized the full-length Noxo1b, Noxo1c, Noxo1a, and Noxo1d by PCR-mediated ... ª 2006 The Authors Journal compilation ª 2006 FEBS 3677 Expression and function of Noxo1c, an alternative splicing form of the NADPH oxidase org...

Ngày tải lên: 19/02/2014, 06:20

... pro-IL-1b and TNF-a expression in MSCs in the presence and absence of BAY 11 -7082 or MG132. *, nonspecific band. (C) Representative western blots for pro-IL-1b expression in MSCs in the pres- ence and ... the phosphorylation and ubiquitin-related degradation of IjB. The active form of NF-jBp65 is then released and translocated into the nucleus to activate the...

Ngày tải lên: 18/02/2014, 04:20

... p.n.cockerill@leeds.ac.uk (Received 18 December 2 010 , revised 10 February 2 011 , accepted 5 April 2 011 ) doi :10 .11 11/ j .17 42-4658.2 011 .0 812 8.x Chromatin is by its very nature a repressive environment which restricts the recruitment ... Fortier C (19 89) The limits of the DNase I-sensitive domain of the human apolipoprotein B gene coincide with the locations of...

Ngày tải lên: 14/02/2014, 18:20

... not only by the prosegment, but also by the 13 residues of the N-terminal of the mature enzyme and by the ÔflapÕ. The anchorage of the prosegment and of part of the N-terminus in the active site ... different clans based on their evolutionary relationship and tertiary structure. Plant APs have been distributed among families A1, A3, A 11 and A12 of clan...

Ngày tải lên: 19/02/2014, 12:20

... Shimadzu). The open reading frames of isoform 1, isoform 2, and M33S KLK 11 were then subcloned into pEU-3b between the XhoI and KpnI sites (pEU ⁄ isoform 1, isoform 2, and M33S KLK 11, respectively). The ... secretory KLK 11, isoform 1, although the pri- mary transcript 1 contained exons 1b and 1c. Tran- script 2 encoded another type of KLK 11, isoform 2, despite t...

Ngày tải lên: 19/02/2014, 06:20

... with TRH (Tyr 113 , Asn 117 , Tyr287 and Arg 311 ), and the two Cys residues (10 5 and 18 6) that form a disulfide bond between EL1 and EL2 to maintain the receptor in a high affinity conformational state. ... about 16 % [12 ,13 ]. Both contain seven copies of the TRH progenitor sequence, whereas only five TRH units are found in the rat and mouse [14 ,15 ], and six in...

Ngày tải lên: 21/02/2014, 03:20

... ursula.kummer@bioquant. uni-heidelberg.de (Received 10 January 2 011 , revised 31 May 2 011 , accepted 15 June 2 011 ) doi :10 .11 11/ j .17 42-4658.2 011 .08 217 .x Systems biology has received an ever increasing interest during the last decade. ... Net flux of glucose through the oxidative PPP accounts for close to 10 % of the total hexose influx. The reductant produced by...

Ngày tải lên: 14/02/2014, 14:20

... TGF, transforming growth factor. 16 10 FEBS Journal 278 (2 011 ) 16 10 16 18 ª 2 011 The Authors Journal compilation ª 2 011 FEBS repression of their target genes, which results in the reg- ulation and ... MAPK, AP -1, NFIB, RASV12, ID -1 [18 ,64] miR -13 2 MeCP2 MeCP2 [65] miR- 61 VAV1 LIN -12 ⁄ Notch [26] A. Ichimura et al. miRNAs and cell signaling FEBS Journal 278 (2 011 )...

Ngày tải lên: 14/02/2014, 19:20

... 278 (2 011 ) 15 98 16 09 ª 2 011 The Authors Journal compilation ª 2 011 FEBS 16 03 IGF2 ⁄ H19 locus, and miR-335, miR-29a and miR-29b at the MEST ⁄ KLF14 locus [ 61] . However, the imprint- ing and expression ... NR6A1 PLAG1 391p, 3501c, 4389c [88] miR -19 3a Intergenic 17 q 11. 2 E2F6 12 7c [40,47] PTK2 545p MCL1 315 c a miR -19 6a-2 Intragenic 12 q13 .13 EST [89] miR -19...

Ngày tải lên: 14/02/2014, 19:20

... 13 9 14 5 of ABCA1 3¢ UTR ⁄ Position 14 9 15 5 of ABCA1 3¢ UTR 8mer ⁄ 8mer ⁄ 8mer [11 5 11 8] MicroRNAs and cardiovascular diseases K. Ono et al. 16 28 FEBS Journal 278 (2 011 ) 16 19 16 33 ª 2 011 The Authors ... Sci USA 10 1, 11 245 11 250. K. Ono et al. MicroRNAs and cardiovascular diseases FEBS Journal 278 (2 011 ) 16 19 16 33 ª 2 011 The Authors Journal compilation ª...

Ngày tải lên: 14/02/2014, 19:20