Tài liệu Báo cáo khoa học: Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates pdf

... Data Bank (accession numbers 2dt9 and 2zho). Determination of quaternary structure The subunit organization of TtAKb was analyzed by analyt- ical ultracentrifugation and gel filtration chromatography. Fig. ... biosynthetic pathway catalyzed by a monofunctional aspartokinase. Acta Crystallogr F 62, 962–966. 20 Yoshida A, Tomita T, Kurihara T, Fushinobu S, Kuzuyama T & Nishiya...

Ngày tải lên: 18/02/2014, 08:20

... The Authors Journal compilation ª 2006 FEBS Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction ... suite: programs for protein crystallo- graphy. Acta Crystallogr D Biol Crystallogr 50, 760–763. 28 Navaza J (1994) Amore – an automated pa...

Ngày tải lên: 19/02/2014, 05:20

... ascomycete fungal laccase from Thielavia arenaria – common structural features of asco-laccases Juha P. Kallio 1 , Chiara Gasparetti 2 , Martina Andberg 2 , Harry Boer 2 , Anu Koivula 2 , Kristiina Kruus 2 , Juha ... Electron Corporation, Waltham, MA, USA). The reactions were started by addition of substrate, and the rate of substrate oxidation was measured by monitoring the chang...

Ngày tải lên: 14/02/2014, 18:20

... atoms) and r j is the standard deviation of B factors. The normalized B factors have a zero mean and unit variance. All atoms that satisfy B z ‡ 4 are treated as outliers and discarded. After ... (1999) Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha. Nat Struct Biol 6, 388–397. 12 Hodel MR, Corbett AH &...

Ngày tải lên: 14/02/2014, 19:20

... structure and catalysis. Biochemistry 48, 3417–3424. 31 Nakamura T, Matsumura H, Inoue T, Kai Y, Uegaki K, Hagihara Y, Ataka M & Ishikawa K (2005) Crystallization and preliminary X-ray diffraction analysis ... Suzuki 5 and Yasushi Kawata 3,4 1 National Institute of Advanced Industrial Science and Technology, Ikeda, Osaka, Japan 2 Department of Food Science and Nutrition, Fac...

Ngày tải lên: 14/02/2014, 22:20

... RHGXRXP and HD, and hydrolyze metal-free phytate with pH optima in the acidic range. They consist of two domains, a large a ⁄ b domain and a small a domain with the catalytic site at the interface of ... glucose- 1-phosphatase and human prostatic-acid phosphatase. The polypeptide chain is organized into an a and an a ⁄ b domain, and the active site is located in a...

Ngày tải lên: 16/02/2014, 09:20

... reactive loop sequences are Val-Ser-Ala-ArgflMet-Ala-Pro and Phe-Thr-Phe-Argfl- Ser-Ala-Arg for PAI-1 and PCI, respectively [6]. By contrast, the reactive site loops of a 1 -antichymotrypsin and ... that the SEA domain functions by orienting the active site cleft of DESC1 toward plasma and ⁄ or extracellular spaces and away from the cell surface and ⁄ or the extracellular...

Ngày tải lên: 19/02/2014, 00:20

... Ivanova N, Sorokin A, Anderson I, Galleron N, Candelon B, Kapatral V, Bhattacharyya A, Reznik G, Mikhailova N, Lapidus A et al. (2003) Genome sequence of Bacillus cereus and comparative analysis with ... part folds into a structure consisting of two hydrogen-bon- ded antiparallel b-strands (b6–b7), an a- helical hairpin (helices a5 , a6 ) and a C-terminal strand (b8). Helix...

Ngày tải lên: 19/02/2014, 00:20

... Andreozzi L, Federico C, Motta S, Saccone S, Sazano- va AL, Sazanov AA, Smirnov AF, Galkina SA, Lukina NA, Rodionov AV et al. (2001) Compositional mapping of chicken chromosomes and identification ... T, Yamagata T, Fukagawa T, Sugaya K, Ando A, Inoko H, Gojobori T, Fujiyama A, Okumura K & Ikemura T (1997) Precise switching of DNA replication timing in the GC content transition are...

Ngày tải lên: 19/02/2014, 07:20

... The Research Council of Norway and Biotec Pharmacon ASA. References 1 Rao MB, Tanksale AM, Ghatge MS & Deshpande VV (1998) Molecular and biotechnological aspects of micro- bial proteases. Microbiol ... N-terminal pro domain is autocatalytically cleaved off when the enzyme has obtained its active conforma- tion, and the two C-terminal domains are cleaved off by heat treatment...

Ngày tải lên: 19/02/2014, 07:20