... Regulation of mitochondrial respir-ation by nitric oxide inhibition of cytochrome c oxidase.Biochim Biophys Acta 1504, 46–57.20 Cadenas E, Poderoso JJ, Antunes F & Boveris A (2000)Analysis of ... presence of this enzyme in different tissues with properties of endothelial NOS, nNOS, and ⁄ or iNOS [14,31,32]. Indifferent models of sepsis and tissues, the existence of both mtNOS and i-mtNOS isoforms ... formation of O2–through the partial reduc-tion of oxygen by one electron. Subsequent reduction by one or two electrons can yield H2O2, and HO, respect-ively [46]. However, the main source of...