Tài liệu Báo cáo khoa học: Globin gene family evolution and functional diversification in annelids ppt

... between circulating and noncirculating intracellular globin and extracellular globin genes in annelids: these genes prob- ably evolved from a common globin- like gene ancestor and did not emerge independently ... 2007) doi:10.1111/j.1742-4658.2007.05799.x Globins are the most common type of oxygen-binding protein in annelids. In this paper, we show that circulating intrac...

Ngày tải lên: 19/02/2014, 02:20

... participating Table 1. Amino acid frequencies (%) in a-amylase linkers, in a set of globular proteins, in the Swiss-Prot databank and in intrinsically unstructured proteins. Amino acid Linkers a Globular proteins b Swiss-Prot c Intrinsically unstructured proteins b Ala ... of this domain in recently available sequence and genome databanks. Interestingly, this domain was found i...

Ngày tải lên: 14/02/2014, 18:20

... dopamine treatment, overexpres- sion of a-synuclein significantly affected the levels of four proteins [stathmin 1, glutathione S-transferase (GST)p, Ran 1 binding protein and C1q binding pro- tein], ... could be involved in determining the effects of dopamine treatment and a-synuclein overexpression. Accordingly, we transfected b-gal and a-syn cells with the pNF-jB-Luc reporter gene...

Ngày tải lên: 15/02/2014, 01:20

... prosodic information, namely pitch and pause, to assist syntactic and semantic analysis during parsing. 1. INTRODUCTION In attempting to merge speech recognition and natural language understanding ... produce three possible interpretations: [old men (in glasses)] and [(old) women in glasses] (5.6a) [old men] and [women in glasses] (5.6b) [old men (in glasses)] and [...

Ngày tải lên: 20/02/2014, 21:20

... the MuvB proteins Lin-37, Lin-52, Lin-54 and chromatin- associated Lin-9 and Lin-53 ⁄ RBBP4 ⁄ RbAp48. Furthermore, A-Myb and B-Myb were present in immunoprecipitations for Lin-9, Lin-37 and Lin-54 [90,92]. ... E2F1, -2 and -3. These acti- vating E2Fs cooperate with NF-Y proteins binding to CCAAT-boxes and with Myb proteins associating with a distal Myb site in activating the C...

Ngày tải lên: 16/02/2014, 09:20

... mechanisms underlying increased cardioprotection in younger female mice are unclear. We hypothesized that serine-threonine protein kinase (protein kinase B; Akt) triggers a metabolic gene switch (decreased ... additional insights into this interesting question. Conclusions In summary, we have identified a novel metabolic gene switch (decrease in fatty acid utilization, increase in...

Ngày tải lên: 18/02/2014, 16:20

... ole in the regulation of cell proliferation, including SMC, by inhibiting signalling mol- ecules [ 45–47]. Caveolin-3 is the main isoform in muscle cells, including SMC [30]. Caveolin-1 and caveolin-3 ... membranes. Free binding sites were blocked by incubation overnight at 4 °C in NaCl/P i containing 5% (v/v) nonfat milk and 0.1% ( v/v) Tween-20. Blots were washed in NaCl/P i /Tw...

Ngày tải lên: 19/02/2014, 16:20

... and functional characterization of an intriguing two- domain protein consisting of a Sco domain and a cyto- chrome c domain [85]. It was shown that the Sco domain does not bind Cu(II), and binds ... the discriminating factor for introducing a high-affinity copper-binding site in Sco proteins. Such a general model would mainly delineate prokaryotic Sco proteins as redox-active protein...

Ngày tải lên: 14/02/2014, 18:20

... have included a full list of N-glycopro- teins from C. elegans and a partial list from mouse liver containing the protein (gene) ID, protein name, glycosy- lated sites, and kinds of lectins used ... the concept of glycan profiling, and utilizes lectins, a group of glycan-discriminating proteins. In general, however, the glycan–lectin interaction is relatively weak in comparison with,...

Ngày tải lên: 16/02/2014, 08:20

... astrocytic Ca 2+ transients are accentuated in pathological con- ditions, suggesting the involvement of astrocytic Ca 2+ transients in brain disorders, including epileptic sei- zures. Interestingly, astrocytes also ... transmission both in physiological and in pathophysiological conditions. In this minireview, the mechanisms underlying syn- chronous Ca 2+ transients in astrocyte...

Ngày tải lên: 16/02/2014, 09:20