Tài liệu Báo cáo khoa học: Progress for dengue virus diseases Towards the NS2B–NS3pro inhibition for a therapeutic-based approach ppt

... inducing plasma leakage, shock and hemorrhagic manifestations. Currently, there are no vaccines available against dengue virus, although several tetravalent live-attenuated dengue vaccines are in ... Journal 274 (2007) 2986–3002 ª 2007 The Authors Journal compilation ª 2007 FEBS REVIEW ARTICLE Progress for dengue virus diseases Towards the NS2B–NS3pro inhibition for...

Ngày tải lên: 19/02/2014, 00:20

... Ascorbate peroxidase Euglena gracilis FraganaAPX O48919 Ascorbate peroxidase Fragaria x ananassa GaldparAPX Q8GT26 Hybrid-type ascorbate peroxidase (Rhodophyta) Galdieria partita GeobactCP AAR35476 ... ttp://www-sequence.stanford.edu/group/candida. Abbreviation Accession number Enzyme Organism (strain) ArathaAPXc Q05431 Ascorbate peroxidase 1 Arabidopsis thaliana ArathaAPXt Q42593 Ascorbate p...

Ngày tải lên: 19/02/2014, 16:20

... summarization Ani Nenkova University of Pennsylvania Philadelphia, PA 19104, USA nenkova@seas.upenn.edu Annie Louis University of Pennsylvania Philadelphia, PA 19104, USA lannie@seas.upenn.edu Abstract Different ... summaries. This fact has favorable implications for practical system developments be- cause it indicates that in applications where some- what longer summaries are appropriate,...

Ngày tải lên: 20/02/2014, 09:20

... of a single globular catalytic domain, with the noticeable exception of the a- amylase from the bacte- rium Pseudoalteromonas haloplanktis, which displays an additional small (21 kDa) C-terminal ... in nonvertebrate animals, and invariably connected via a linker to an animal-type a- amylase (listed in Table S1), as shown in Fig. 1. More specifically, the primary structure of thes...

Ngày tải lên: 14/02/2014, 18:20

... mode, the increase in ADP–ATP exchange rate mediated by the ANT decreases to 1.7%. It should be noted that the greatest increase in the ADP–ATP exchange rate medi- ated by the ANT calculated at ... littermates. The above calculations afford the assumption that a 30% increase in F 0 F 1 -ATP synthase activity will lead to an insignificant increase (1.38–1.7%) in the ADP–ATP ex...

Ngày tải lên: 14/02/2014, 19:20

... Y, Sagara H, Kabe Y, Azuma M, Kume K, Ogawa M, Nagai T, Gillespie PG, Sasakawa C & Handa H (2007) The enteropathogenic E. coli effector EspB facilitates microvillus effacing and antiphago- cytosis ... 213–222. 66 Hamaguchi M, Hamada D, Suzuki KN, Sakata I & Yanagihara I (2008) Molecular basis of actin reorgani- zation promoted by binding of enterohaemorrhagic Escherichia coli EspB t...

Ngày tải lên: 14/02/2014, 22:20

... nucleic acid-binding proteins. Database Structural data for the two RNase A complexes are available in the Protein Data Bank under accession numbers 2xog and 2xoi Abbreviations PDB, Protein Data Bank; ... USA Introduction Upon catalyzing the cleavage of RNA, RNases operate at the crossroads of transcription and translation. Bovine pancreatic RNase A (EC 3.1.27.5) is the best c...

Ngày tải lên: 14/02/2014, 22:20

... acetyl-CoA car- boxylase; AMPK, 5¢ AMP kinase; CPT, carnitine palmitoyltransfer- ase; FAS, fatty acid synthase; MCD, malonyl-CoA decarboxylase; OAA, oxaloacetate; TCA, tricarboxylic acid. M. J. Wolfgang ... [41–45]. There are at least six carnitine acyltransferases in mammals [46]. Carnitine acetyltransferase and carni- tine octonyltransferase mediate the transfer of acetyl and short- to me...

Ngày tải lên: 14/02/2014, 22:20

... substrate-free AppA the C a atoms are 2.41 A ˚ apart, whereas for the substrate-free PhyK and the substrate-loaded AppA the averaged distance is only 1.87 A ˚ . Distinct conformational changes ... phytate with pH optima in the acidic range. They consist of two domains, a large a ⁄ b domain and a small a domain with the catalytic site at the interface of the two...

Ngày tải lên: 16/02/2014, 09:20

... 5¢-GGAGATCTCCAGTGA TATCGACCA-3¢ and 5¢-ACGGCTTCTACGGATCGAA ACT-3¢ for PPARc ,5¢-AAGACAGCTCCTCCTCGAAGG TT-3¢ and 5¢-TGACCAAATCCCCATTTACGC-3¢ for aP2, 5¢-ATCCATGGATGGACGGTAACG-3¢ and 5¢-CTGGA TCCCAATACTTCGACCA-3¢ ... 5¢-GCGTCGGGTAGATCCAGTT-3¢ and 5¢-CTC AGTGGGGCTTAGCTCTG-3¢ for ACC, and 5¢-AACAC CCCAGCCATGTACGTAG-3¢ and 5¢-TGTCAAAGAAA GGGTGTAAAACGC-3¢ for b-actin. Expression levels of...

Ngày tải lên: 16/02/2014, 09:20