Tài liệu Báo cáo khoa học: The stereochemistry of benzo[a]pyrene-2¢-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases pptx
... with the levels
of DNA methylation, and thus the effect of the abso-
lute configurations and conformations of the adducts
on DNA methylation was not evaluated. More
recently, the effect of stereochemically ... (2007) 2121–2134 ª 2007 The Authors Journal compilation ª 2007 FEBS
The stereochemistry of benzo[a]pyrene-2¢-deoxyguanosine
adducts affects...
... mediated by the
tracheal system, a network of tubules that open to the
atmosphere on the cuticle and radiate to all parts of
the body. O
2
is delivered through trachea and trache-
oles in the gaseous ... indication of the presence of hemocyanin
(data not shown). The notion of the absence of hemo-
cyanins from Holometabola is corroborated by the fact
that...
... (see
below). The effect of the additives on aggregation of the
target protein (in the absence and presence of aB-crystallin)
was assessed at the end of each assay by calculating the
percentage ... aB-crystallin (i.e. the effect of
the additive on the aggregation of the target protein is inde-
pendent and different from that of the chaperone). The
st...
... times of digestion, more
than 50% of the sample was converted into the frac-
tion S. Breaking the disulfate bond in the middle of
the crosslinker produced only mononucleosomes and
the band S. DNA ... rest, even by the
zero-length crosslinker, perhaps via linker histones H1
and H5. Indeed, there is evidence that the tails of these
histones follow the path of...
... prevented by blocking transport from
the ER to the Golgi. BFA had no effect on the relative
lack of the 130 kDa isoform of the K650M mutant.
Endo H digestion of the immunoprecipitated wild-type
and ... and located in different domains of the recep-
tor (Fig. S1) was created by site-directed mutagenesis
of the full-length human FGFR3 cDNA and subclon-
ing in...
... electrostatic field of different
Fig. 5. Plot of the EIE values as function of rotation (r) and inclination (i) angles of RNases. The hatched axis at the bottom and right of the
plots show schemes of some ... DMPG membranes, as evidenced
by a decrease of the amplitude of their thermotropic
transition. Only RNase A and RNase AA show no
effects on the thermotr...
... from the deleterious effects of DNA injury a net-
work of genome care-taking mechanisms has evolved of which a
set of DNA repair systems constitute a key component. The
clinical impact of the DNA ... undergoes fusion with the
membrane of intra-endosomal vesicles contained within MVBs,
thereby releasing the nucleocapsid into the lumen of these vesi-
cles. Then,...
... Electron density of RTA R213D in the vicinity of residue 213. The backbone and sidechains of the R213D substitution are shown as stereo
images in thick ball and stick and the position of the Arg213 ... by the addition
of 100 lLof2· Kirby buffer [25] and 80 lLofH
2
O, and
rRNA was obtained by precipitation after two phenol–
chloroform extractions. Four micro...
... the lysozyme of
the bivalve Tapes japonica [3], with the so-called chlamysin
of Chlamys islandica [4,5], and also with a hypothetical
secreted protein of the nematode Caenorhabditis elegans and
with ... between this plot
and the corresponding part of the HCA plot of the Asterias
lysozyme. The same overlap is obtained when comparing
the human lysozyme and/ or...
... revealed the existence of two additional
subunits (bringing the total to 46), and one of these, the
ESSS protein, is also encoded by an X-linked g ene in
humans and mouse [36]. Most of these subunits ... the level of a complex of 46 subunits is
determined.
The activities of complex II and the downstream complex
III of the electron transport chain were measu...