Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of transcription factors ppt

... MINIREVIEW Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients Takuji Iwamoto 1,2 , Hiroshi Okamoto 1 , Yoshiaki Toyama 2 and Shigeki Momohara 1 1 Institute of Rheumatology, ... Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan Introduction Rheumatoid arthritis (RA) is a chronic systemic inflam- matory disease t...

Ngày tải lên: 18/02/2014, 18:20

... MINIREVIEW Molecular aspects of rheumatoid arthritis: role of environmental factors Shu Kobayashi, Shigeki Momohara, Naoyuki Kamatani and Hiroshi Okamoto Institute of Rheumatology, Tokyo ... genetic factors are responsible for 50–60% of the risk of devel- oping RA. Thus, environmental factors may explain the remaining risk of developing RA. A large variety of env...

Ngày tải lên: 18/02/2014, 18:20

... MINIREVIEW Molecular aspects of rheumatoid arthritis: role of transcription factors Hiroshi Okamoto 1 , Thomas P. Cujec 2 , Hisashi Yamanaka 1 and Naoyuki Kamatani 1 1 Institute of Rheumatology, ... factors. In this review, we focus on the role of transcriptional factors on the pathology of rheumatoid arthritis (RA). Nuclear factor-jB The nuclear factor-jB (NF-j...

Ngày tải lên: 18/02/2014, 18:20

... molecular mode of action of glypho- sate and the molecular basis for glyphosate resistance. Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... GriP. Of partic- ular note is a short, 2.46-A ˚ hydrogen bond between N- e of His138 and a phosphate oxygen of GriP. Alanine substitutions at selected positions allowed...

Ngày tải lên: 14/02/2014, 14:20

... essen- tial role of the HR-A ⁄ B is to maintain the structural integrity of the HSF trimer, because an HSF deriva- tive containing the dimerization domain of transcription factor Gcn4 instead of the ... implicated not only in the coop- erative binding of HSF to the DNA, but also in transcriptional activation [36]. Although the role of hyperphosphorylation in transcriptional...

Ngày tải lên: 18/02/2014, 04:20

... of the enzyme-excluded solution from that of the enzyme-containing solution and was expressed as nmols of 2,6-dichloroindophenol reduced per mg of protein per min. The extinction coefficient of ... Department of Agricultural and Environmental Biology, Graduate School of Agricultural and Life Sciences, University of Tokyo, Japan 2 Institute of Genetic Resources, Graduate Schoo...

Ngày tải lên: 18/02/2014, 04:20

... (A) Scheme of the three-hybrid strategy used in the screen. (B) Number of colonies identified in each step of the screen. (C) Distribution of the 63 distinct sequences in relation of their position ... Mayer KF, Schoof H, Haecker A, Lenhard M, Jurgens G & Laux T (1998) Role of WUSCHEL in regulating stem cell fate in the Arabidopsis shoot meristem. Cell 95, 805–815. 48 Schoof...

Ngày tải lên: 18/02/2014, 06:20

... Approximately 0.4 mg of protein was treated with 10 mU of glycosidase F (Sigma-Aldrich Inc.) at 37 °C for 16 h. For crosslinking of proteins, slices of cotyledons were homogenized with 20 strokes of a Dounce ... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-...

Ngày tải lên: 18/02/2014, 11:20

... Ollivaux C & Soyez D (2000) Dynamics of biosynthe- sis and release of crustacean hyperglycemic hormone isoforms in the X-organ-sinus gland complex of the crayfish Orconectes limosus. Eur J ... Soyez D (2002) Enkephalinergic control of the secretory activity of neu- rons producing stereoisomers of crustacean hyperglyce- mic hormone in the eyestalk of the crayfish Orconectes lim...

Ngày tải lên: 18/02/2014, 11:20

... (2005) On the importance of carbohydrate- aromatic interactions for the molecular recognition of oligosaccharides by proteins: NMR studies of the struc- ture and binding affinity of AcAMP2-like peptides ... Use of the Amber force-field in conformational-analysis of carbo- hydrate molecules – determination of the solution conformation of methyl alpha-lactoside by NMR-spec- tros...

Ngày tải lên: 18/02/2014, 17:20