Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt

... phosphorylated ERK, p38 and JNK (p-ERK, p -p38 and p -JNK) and total ERK, p38 and JNK (tERK, tp38 and tJNK). (B) The ratio of phosphorylated to total ERK (p44 ⁄ 42), p38 and JNK at each time point. The data ... JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves Aiguo Shen 1, *, Junling Yang 2, *, Yangyang G...

Ngày tải lên: 18/02/2014, 18:20

... correct link with an incorrect label, and 1 for an incorrect link. Since the history-based feature set used in the parsing algorithm makes it impossible to use inde- pendence to factorize the scoring ... has spurred a growing interest of related research in the machine learning community, which in turn has led to improved results in a wide range of applications in NL...

Ngày tải lên: 20/02/2014, 12:20

... leading to autophosphoryla- tion of tyrosine residues on the cytoplasmic domain of the receptor, thereby creating docking sites for adaptor pro- teins, such as Shc and G rb2. The latter protein ... indu ce expression of genes involved in cell cycle progression include Elk1, c-fos, c-Jun and c-myc [9,15]. The duration of ERK activation (transient or sustained) determines th...

Ngày tải lên: 19/02/2014, 16:20

... inactivation of matrix proteins and various protease inhibitors, including antithrombin, C1 inhibitor, heparin cofactor II, and a 2 -antiplasmin [10]. Previous reports have described the interactions of TFPI ... the interactions between TFPI and serine proteinases derived from the secretory granules of in ammatory cells. To investigate the functional role of TFPI in inflam-...

Ngày tải lên: 19/02/2014, 00:20

... evolutionary elaboration of the HBL-Hb structure simultaneously involved the possibility for globins and linkers (proteins involved in the structure of HBL-Hb) to interact and to bind to dimers or other ... 2007) doi:10.1111/j.1742-4658.2007.05799.x Globins are the most common type of oxygen-binding protein in annelids. In this paper, we show that circulating intracellul...

Ngày tải lên: 19/02/2014, 02:20

... detailed e xamination of the steps involved in subunit d issociation and reassociation will contribute to a better understanding of the dimerization process per se and the role of interprotomeric contacts ... preparation of apo-CcStP and the characterization thereof in respect to structural properties and kinetic stability. The process of reconstitution with PLP has...

Ngày tải lên: 19/02/2014, 16:20

... functional importance of invariant amino acids of the corresponding alpha-helical C-terminal globular domain of human PrP C can be demonstrated with Pro102, Ala117, and Gly131 variants of human PrP C . ... corresponding to gb|BM071383| and including the putative initiator methionine was ordered from the Resource for the German Genome Project (RZPD), Berlin, Germany, double stran...

Ngày tải lên: 19/02/2014, 16:20

... the S100 family of Ca 2+ - binding proteins and are now accepted as markers of in ammation. They are expressed by keratinocytes and in ammatory cells in human ⁄ murine wounds and by appropriately ... is important in cell proliferation, differentiation, embryo- genesis and synthesis of in ammatory cytokines [43,52] and is essential for S100A8 induction in macrophages...

Ngày tải lên: 19/02/2014, 18:20

... chain into N-terminal and C-terminal centers during refolding [21]. Since then, many scientists have been interested in demonstrating this concept by using N-terminal and C-terminal fragments of ... located in the C-terminal loop of SNase plays an important role in protein stability and conforma- tional integrity. During protein unfolding ⁄ refolding, the addition of 2.5 p...

Ngày tải lên: 20/02/2014, 01:20

... and vice-versa. We apply clus- tering and distributed representations to NER and chunking, which allows us to compare our semi-supervised models to those of Ando and Zhang (2005) and Suzuki and ... Collobert and Weston (2008) embeddings, and HLBL (Mnih & Hinton, 2009) embeddings of words on both NER and chunking. We use near state -of- the-art supervised baseli...

Ngày tải lên: 20/02/2014, 04:20