Tài liệu Báo cáo khoa học: Leptin protects H9c2 rat cardiomyocytes from H2O2-induced apoptosis docx

... Leptin protects H9c2 rat cardiomyocytes from H 2 O 2 -induced apoptosis Megumi Eguchi*, Yuantao Liu*, Eyun-Jung Shin and Gary Sweeney Department ... mentioned above, leptin- or leptin receptor-deficient rodents dis- play an increased rate of cardiac apoptosis. The increase in apoptotic rate and mortality was abolished upon leptin injection ... that leptin exerts a protect...

Ngày tải lên: 18/02/2014, 18:20

... the results demonstrate that this bacterium has a complete, albeit bifurcated, TCA cycle; oxaloacetate flows to succinate both through citrate/-ketoglutarate and via malate/ fumarate ODE sim, fit ... HV (2000) Biophys J 78, 1087 –1093. 21 Carbohydrate, glycolysis Saccharomyces cerevisiae It is demonstrated that a model of yeast glycolysis can be constructed from in vitro data. The model is te...

Ngày tải lên: 14/02/2014, 14:20

... values of Y obtained from equilibrium and kinetic experiments, respec- tively. The continuous line was generated from Eqn (3) with K = (1.5 ± 0.2) · 10 )5 M. The HSA-heme-Fe(III) concentration was 3.3 ... experimen- tal conditions investigated (Table 1). Determination of nitrite, nitrate and S-nitrosothiols The concentrations of nitrite, nitrate and S-nitroso- thiols were determined after...

Ngày tải lên: 16/02/2014, 14:20

... sub- strates. That microbial cell death may result from nonspecific interference of cationic amphipathic peptides with the dynamic organization of membrane- bound pathways rather than just from ... could promote the cellular penetration properties of antimi- crobial peptides, it is noticeable that microbial cell- penetrating antimicrobial peptides and antimicrobial cell-penetrating peptide...

Ngày tải lên: 18/02/2014, 06:20

... structurally characterized NHs from parasitic protozoa, including NHs from Crithidia fasciculata [7,26], Leishmania major [9] and Leishmania donovani [10], from Bacteria, such as NHs from E. coli YeiK and ... molecular mass studies were obtained from Sigma (St Louis, MO, USA). IPTG was from Applichem (Darmstadt, Germany). Sephacryl S-200 and AH-Sepharose 4B were obtained from Am...

Ngày tải lên: 18/02/2014, 17:20

... triplicate for each substrate concentration. The k cat values were calculated using the for- mula V max ⁄ [enzyme]. The amount of fluorescence emitted per nmol substrate was calculated from a standard ... RNase- Alert substrate at various concentrations of NaCl were then corrected with respect to the values obtained using an equal amount of DNaseAlert substrate. Equal concentrations of enzym...

Ngày tải lên: 19/02/2014, 05:20

... production rate. A switch from a high rate to a low rate of production occurs when s 1 exceeds the threshold s 0 at the inflection point (Fig. 4D) and this could correspond to a sub- strate-inhibition ... substrate concentra- tion but not at a high concentration where the sub- strate would become available for enzymes in a different metabolic pathway. A strongly sigmoid curve from low to h...

Ngày tải lên: 19/02/2014, 06:20

... percentages of 60% and 73% and their substrate binding residues are identical with one important exception: the C-terminal part starting from Val660 has been deleted from NP_610129 and hence the third ... mutation rates of amino acids involved in substrate binding and to find other essential amino acids. Finally, we pinpointed signal sequences, and transmembrane and lipid anchor sequences...

Ngày tải lên: 19/02/2014, 13:20

... transform Arabidopsis plants via vacuum infiltration. Regeneration of fertile Arabidopsis transformants w as successful only from the seed progeny collected from plants transformed with constructs ... cytokinin cleavage involving a ternary enzyme–substrate–electron acceptor complex formation indicates that previously used concen- trations of substrate and electron acceptors in the reaction...

Ngày tải lên: 19/02/2014, 16:20

... an estimate from a component phrase table, and each λ m is a weight in the top-level log-linear model, set so as to maximize dev-set BLEU using minimum error rate training (Och, 2003). We learn separate weights ... the mixture operation used for combining the scores, we would get different mix- ture scores. The choice of mixture operation will be discussed in Section 3.1. Figure 1 illustrat...

Ngày tải lên: 19/02/2014, 19:20