Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc

... remodeling regulates integrin and E-cadherin function Integrin sugar chains play important roles in the biological functions of integrins A growing body of evidence indicates that the presence of the ... site. The C-terminal segments traverse the plasma membrane and mediate interactions with the cytoskeleton and with signaling molecules. On the basis of exten...

Ngày tải lên: 18/02/2014, 17:20

... understand the biological significance of the differ- ence in TnI–TnC interactions, we compared the ability of TnC to neutralize the inhibitory effects of the C-ter- minal fragments in the presence and ... ATnI 130)252 , and ATnI 232)292 did not migrate into the gels, while free ATnI-52K and ATnI 1)128 exhibited a band near the origin and at the middle of t...

Ngày tải lên: 20/02/2014, 01:20

... the condensation and fragmentation of their nuclei. The percentage of apoptotic cells was calculated as the number of apoptotic cells divided by the total number of cells counted. A minimum of ... lost. Taken together, our results demonstrate an impor- tant relationship among the regulation of nucleo- lin ⁄ C23, the activation of caspase-3 and the induction of...

Ngày tải lên: 16/02/2014, 09:20

... the role of estrogen receptors in muscle glucose metabolism is unknown. Therefore, we investigated the expression of the two estrogen receptors, ERa and ERb and their influence on regulation of GLUT4, ... rhythyms as their bases. The observables of the culture pro- vide us with a unique insight into the temporal organization of the living state in every cell and a...

Ngày tải lên: 19/02/2014, 07:20

... (2004) and in the scheme “EN” of Habash and Sadat (2006). In Lee (2004), the goal is to match the lexical granularities of the two languages by starting with a fine-grained seg- mentation of the ... occurrence of two phrase pairs in a Turkish-English parallel corpus and the two hypothesized sets of segmentations for the Turkish phrases as in Table 1. Without ac- c...

Ngày tải lên: 20/02/2014, 04:20

... the dependency relation of the event and that of the de- pendency relation of the sentence. Our aim was to achieve a balance between the specificity of depen- dency paths and the generality of dependency pairs. In ... E  e and E  s , the descendant -of relation of the event descrip- tion e and the sentence s, respectively. We use the following, two-ti...

Ngày tải lên: 20/02/2014, 09:20

... subset of the available modalities, e.g. voice and pen, and then the full set of modalities. By giving the users dif- ferent subsets in the first part, we can compare if the enforcement of certain ... On the other hand, they can freely formulate queries relating to the information they are looking for, e.g. “Did they decide to put a sofa in the lounge?”. Commands are...

Ngày tải lên: 20/02/2014, 12:20

... and 482) and one Thr residue (amino acid 487) were well conserved in the KIND2 of v-KIND in all species analyzed, although not in the other KINDs. To investigate the possible involvement of these ... downstream of v-KIND overexpression [12]) enhances the activity of MAP2 to bind to microtubules and promote their assembly [18], and that the inhibition of JNK1 (such...

Ngày tải lên: 14/02/2014, 19:20

... birds, mammals and corals is the dmrt gene family [5]. The prototype members of this group of factors are the Drosophila doublesex (dsx) and Caenor- habditis mab-3 genes. The Dmrt group of molecules ... gene is the product of a gene duplication of the autosomal dmrt1a gene and was designated dmrt1bY [8] or Dmy [9]. It was shown to be the only functional gene in...

Ngày tải lên: 14/02/2014, 19:20

... expression in the fat and liver is associated with development of obesity. RMI1 is the component of the BLM helicase com- plex that maintains complex stability and aids in the maintenance of genome ... the RMI1- deficient mice under normal conditions, except the reduced body weight and lower fasting glucose. Of note is the fact that the deficient mice showed a rate...

Ngày tải lên: 16/02/2014, 09:20