Tài liệu Báo cáo khoa học: Dual P2Y12 receptor signaling in thrombin-stimulated platelets – involvement of phosphoinositide 3-kinase b but not c isoform in Ca2+ mobilization and procoagulant activity pdf

... Journal compilation ª 2007 FEBS 385 Dual < /b> P2Y 12 receptor < /b> signaling < /b> in < /b> thrombin-stimulated < /b> platelets < /b> – < /b> involvement < /b> of < /b> phosphoinositide < /b> 3-kinase < /b> b but not c isoform in < /b> Ca 2+ mobilization and procoagulant activity Paola ... Thrombin, fibrin and platelets,< /b> a resonance loop in < /b> w...

Ngày tải lên: 18/02/2014, 16:20

... receptors, type I–type II receptors Receptor < /b> heterooligomers induced by ligand binding signal via Smads, preformed complexes signal via p38 [31] Receptor < /b> complex inhibiton BAMBI pseudoreceptors block receptor < /b> ... usually by binding to ligand dimers Dimeric secreted proteins such as noggin, chordin, follistatin and GDF3 bind and therby inactivate BMP dimers [16] Cell...

Ngày tải lên: 19/02/2014, 00:20

... probability of < /b> a sequence of < /b> L tags is decomposed as: is the vector of < /b> observations and each is the index of < /b> a spurt. The probability dis- tribution associated with each state of < /b> the Markov chain ... preceding tag and the local observation . However, in < /b> order to incorporate more than one label dependency and, in < /b> particular, to take into...

Ngày tải lên: 20/02/2014, 16:20

... dense accumulation of < /b> gold grains in < /b> the extraspicular space, reflecting dense packaging of < /b> silicatein molecules there also. The silicatein molecules are arranged around the spicules in < /b> concentric rings ... silicatein gene, and, after expres- sion of < /b> silicatein and subsequent incubation with silicic acid, the bacteria had been encapsulated with bio-sil- ic...

Ngày tải lên: 18/02/2014, 16:20

... learnable lexical selection sub-system for a conneetionist transfer project in < /b> machine translation. Dual-< /b> Coding Theory There is a well-known debate in < /b> psycholinguistics concerning the bilingual ... project in < /b> machine translation. Introduction Psycholinguistic knowledge would be greatly helpful, as we believe, in < /b> constructing an artificial language p...

Ngày tải lên: 20/02/2014, 22:20

... specifically binding proteins, which recognize and bind certain RNAs and thus stabilize the RNA structure, thereby forming a stable RNA-protein complex; (b) proteins with RNA chaper- one and annealing ... mechanism(s) of < /b> DEAD-box helicases. The binding sites for double- stranded RNA and ATP overlap, resulting in < /b> coupled binding of < /b> both molecules. Simultaneous bindi...

Ngày tải lên: 14/02/2014, 19:20

... evidence that tBid is a substrate of < /b> the ubiquitin ligase Itch, which can specifically interact with and ubiquitinate tBid, but not intact Bid. Consistently, overexpression of < /b> Itch increases cell ... EGF-induced reduction in < /b> Bid and tBid levels and the ubiquitin ligase activity of < /b> Itch. In < /b> this study, we first examined the ability of < /b> Itch t...

Ngày tải lên: 16/02/2014, 09:20

... signaling < /b> and highlight their potential roles in < /b> mRNA processing. Abbreviations ASCOM, activating signal cointegrator-2 (ASC2) complex; CBP, CREB-binding domain; CGBP, CpG-binding protein; ER, ... a common structural organization that includes a DNA-binding domain, a ligand-binding domain and a transactivation domain. The DNA-bind- ing domain is responsible for DNA binding s...

Ngày tải lên: 16/02/2014, 14:20

... pro- teins are not currently known to be subject to genetic rearrangements in < /b> human cancer. Because the biological activity of < /b> MLL is restricted to open chromatin structures, in < /b> particular, to active ... second explanation is the inhibitory effect of < /b> mostly all GSK3 inhibitors against certain CDKs, including CDK9 [39]. As outlined above, inhi- bition of < /b>...

Ngày tải lên: 16/02/2014, 14:20

... dephosphor- ylation of < /b> b- catenin and cause b- catenin accumulation in < /b> the nuclei of < /b> HFL-1 lung fibroblasts. Incubation of < /b> LL-86 lung fibroblasts with a-defensin-1 and a-defen- sin-2 also caused increases in < /b> active ... a-defensin-induced increases in < /b> cell proliferation and collagen synthesis of < /b> lung fibroblasts. a-defensin-induced activa...

Ngày tải lên: 18/02/2014, 06:20