Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt

... the performance of the potential will only increase with the size of the structural database and as terms are added to the model to account for protein and RNA intra-molecular interactions that are ... knowledge-based potential function predicts the specificity and relative binding energy of RNA -binding proteins Suxin Zheng 1, *, Timothy A. Robert...

Ngày tải lên: 18/02/2014, 16:20

... biology approach for the analysis of carbohydrate dynamics during acclimation to low temperature in Arabidopsis thaliana Thomas Na ¨ gele, Benjamin A. Kandel*, Sabine Frana*, Meike Meißner and Arnd ... simulation A mathematical model was developed, representing central carbohydrate metabolism in leaves of A. thaliana. The model was based on the following system of ordinary d...

Ngày tải lên: 14/02/2014, 22:20

... l-dopa as cofactor to eliminate the characteristic lag period of tyrosinases [8,20,21]. Figure 3 shows the rate of TH activity as a function of the concentration of l-dopa cofactor added to the assay ... was added for the standard TH assay, and 0.02% SDS was added for DO activity. For dopa titration, 50 lL10mm sodium periodate was added, and the increase in A 475...

Ngày tải lên: 19/02/2014, 07:20

... to pain and was effective in alleviating chronic pain and accelerating functional recovery in an animal model of neuropathy. These data are in agreement with an important role of nAChRs in pain perception, ... or that the functional properties of the nAChR are modified in a cell-specific way. The fact that an anti -a7 mAb selectively inhibited the a- BTX-sensitive current i...

Ngày tải lên: 19/02/2014, 12:20

... is the fact that there is often a good deal of overlap in words between the reparandum and the alteration, as speakers may trace back several words when restarting after an er- ror. For instance, ... use in a special repair grammar, which not only reduces the amount of available training data, but violates our intuition that most reparanda are fluent up until the actual edi...

Ngày tải lên: 20/02/2014, 09:20

... probabilities and Eojeol transition probabilities to create spelling correction candidates. Candidates are increased in number by inserting the blank cha- racters on the created candidates, ... several advantages. Since an Eumjeol is a combination of 3 Jasos, the number of all possible Eumjeols is much larger than that of all possible Jasos. In other words, Jaso-based l...

Ngày tải lên: 20/02/2014, 12:20

... posed of the 2nd candidate at the 1st position, the 1st candidate at the 2nd position and the 3rd candidate at the 3rd position. The architecture described in the previous section can be easily ... The other dimension corresponds to the candi- date level. Candidates on the same level form one stream. For example, in Fig. 6 (a) , the character at the 3rd pos...

Ngày tải lên: 21/02/2014, 20:20

... information for the functional analysis of plant DEVH box RNA helicases, and suggest that AtHELPS, as an impor- tant negative regulator, plays a role in K + deprivation stress. Abbreviations ABA, abscisic ... Temporal and spatial expression of AtHELPS. (A) The relative expression of the AtHELPS gene in shoots and roots at different devel- opmental stages, as revealed by...

Ngày tải lên: 14/02/2014, 18:20

... Ricerca Sanitaria Finalizzata, Ricerca Sanitaria Applicata; Ribovax Biotechnologies (Geneva, Switzerland) and Fondazione Italiana Ricerca sul Cancro (FIRC). References 1 Pancholi V (2001) Multifunctional ... in cervix and colon cancer, leukemia, normal pancreatic ducts and tumoral pancreatic cells. Fourteen acetylated lysine residues are common to leukemia, pancreatic cancer and norma...

Ngày tải lên: 14/02/2014, 19:20

... the dark gray area of the Venn diagram are thought to be relatively abundant in serum, and are primary candidates for further validation. Glycoproteins found in the pale gray area are secondary ... knowledge of human glycosylation, glycan structural analysis systems, the bioinformatics capability and the databases that we have developed over the years, and animal models...

Ngày tải lên: 16/02/2014, 08:20