Tài liệu Báo cáo khoa học: Calcium-binding to lens bB2- and bA3-crystallins suggests that all b-crystallins are calcium-binding proteins pptx

... paradigm that illus- trates the structural parameters required to allow a polypeptide to remain unfolded, extended and flexible. Keywords glycoside hydrolases; intrinsically disordered proteins; ... can wonder why ali- phatic and aromatic residues are not totally avoided in linker sequences to prevent folding. These residues are either clustered (Petrolisthes) or randomly dist...

Ngày tải lên: 14/02/2014, 18:20

... extract translation candidates by identifying consecutive Chinese tokens labeled as B and I. Finally, we compute the frequency of all the candidates identified in all snippets, and output the one ... engine, and automatically annotating the snippets with tags and features for training a conditional random field model. At run- time, the model is used to extracting transla...

Ngày tải lên: 19/02/2014, 19:20

... devices, we now have to add all these data to the genomic and transcriptomic ones. Biological systems are then the only way to put all this information in a comprehensive and clin- ically usable set ... continually expanding towards thousands, and has provision for generating ‘designer’ microarrays from desired sources. I shall describe ligand assignments to classic recept...

Ngày tải lên: 19/02/2014, 07:20

... only a subset of pareto-optimal points. The triangle () is a point that is weakly pareto-optimal but not pareto-optimal. Definition 1. Pareto Optimal: A hypothesis h ∗ ∈ L is pareto-optimal iff ... of Pareto Optimality 2.1 Definitions and Concepts The idea of Pareto optimality comes originally from economics (Pareto, 1906), where the goal is to char- acterize situations when a change in...

Ngày tải lên: 19/02/2014, 19:20

... increased affinity for some lig- ands, such as warfarin [5,18–23]. Fatty acids are effective in allosterically regulating ligand binding to Sudlow’s site I and to the heme cleft. Myristate regulates ... Mn(III)heme affinity to HSA, whereas warfarin and FA7 ligands were reported to behave in the opposite way with respect to ferric heme binding to HSA [19,21,31]. Additionally, t...

Ngày tải lên: 20/02/2014, 02:22

... respect to two metrics: the order in which we visit landmarks and the side we pass them on. To determine the order P e visits landmarks we compute the minimum distance from P e to each landmark, and ... which conjoins the side c we pass the landmark on with each spatial term w ∈ u. This allows us to capture that the word above tends to indi- cate passing to the north of the...

Ngày tải lên: 20/02/2014, 04:20

... extraction using t-test is not accurate and includes number of such bigrams and trigrams that are not actually collocations. Thus, manually such entries were removed and actual collocations were further ... (Sharma R. and Goyal V., 2011b). 2.5 Tokenizer Tokenizers (also known as lexical analyzers or word segmenters) segment a stream of characters into meaningful units calle...

Ngày tải lên: 20/02/2014, 05:20

Ngày tải lên: 20/02/2014, 09:20

... (khyama), special 150 symbol (!), quoted sentence and emotion word ( [happy])) together and all these four fea- tures are important to identify the emotion of this sentence. k o! ... (e.g., bhallo bhallo [good good], khokhono khokhono [when when] etc.) in Bengali are most likely emotion words.  Question words: It has been observed that the question words gen...

Ngày tải lên: 20/02/2014, 09:20

... dialogue domain and task, and, perhaps most importantly, personality characteris- tics and knowledge of the user. We believe that the key to maximum dialogue ef- fectiveness is to listen to the user. ... generally been limited to well defined areas of the dialogue, in particular dealing with speech recognition and clarification problems, with small state spaces and a limited...

Ngày tải lên: 20/02/2014, 12:20