Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleto

Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins pptx

... MINIREVIEW Marine toxins and the cytoskeleton: okadaic acid and dinophysistoxins Carmen Vale and Luis M. Botana Departamento de Farmacologı ´ a, Facultad de Veterinaria, USC, Lugo, Spain Introduction The ... 2008) doi:10.1111/j.1742-4658.2008.06711.x Okadaic acid (OA) and its analogs, the dinophysistoxins, are potent inhibi- tors of protein phosphatases 1 and...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt

... as ostreocin-D or ovatoxin-a) and the extreme acute animal toxicity. The Na + ⁄ K + -ATPase has been proposed as receptor for palytoxin. The marine toxin is known to act on the Na + pump and elicit an increase ... tropical and sub- tropical areas, but recently these dinoﬂagellates have also started to appear in the Mediterranean Sea. Two of the most remarkable properties o...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: pectenotoxins, unusual macrolides that disrupt actin pptx

... rotundata and Dinophysis acuta [1–3,6,10–13]. After consumption of the algae by the shellﬁsh, PTX-2 can be metabolized to other PTX derivatives. In the digestive gland of the scallop P. yessoensis, the ... to the alcohol (PTX-1), aldehyde (PTX-3) and carboxylic acid (PTX- 6) forms [7,13]. Also, PTX-4 and PTX-7 have been isolated from the digestive glands of scallops coll...

Ngày tải lên : 18/02/2014, 14:20

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Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in ﬁsh pdf

... Germany Introduction The phenomenon of two different sexes and conse- quently the necessity to make a developmental decision for an embryo to become male or female (the so-called sex-determination process), and the ... ﬁsh, birds, mammals and corals is the dmrt gene family [5]. The prototype members of this group of factors are the Drosophila doublesex (dsx) and Caenor- h...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: Structural insights into the substrate speciﬁcity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt

... investigation of the catalytic mechanism and substrate speciﬁcity and to understand the differences therein for this class of enzymes. In order to identify the subsites of the ervatamins and to understand ... both the molecules of the asymmetric unit runs along the extended backbone of residues 65–64 and is partly exposed to the solvent (Fig. 2B). On the other hand,...

Ngày tải lên : 18/02/2014, 16:20

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Tài liệu Báo cáo khóa học: Numerical calculations of the pH of maximal protein stability pptx

... be compared. The origin of the optimum pH. The position of the optimum pH depends on the amino acid composition and on the organization of the amino acids within the 3D structure. To ﬁnd which of these ... factor determining the optimum pH and in 68% of the cases, the 3D structure does. To check for possible correlation between the optimum pH and the pK shift...

Ngày tải lên : 19/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Adaptive changes in the expression of nuclear and mitochondrial encoded subunits of cytochrome c oxidase and the catalytic activity during hypoxia pptx

... catalytic subunits I and II, and the nuclear genome encoded subunits, IV, Vb and VIIa. The mammalian CytOX subunit IV is a homolog of the yeast subunit V, with the latterexpressedinanO 2 and heme regulated ... for cytochrome c [4,5]. The remaining 10 subunits of the mammalian enzyme, namely, IV, Vb, VIa, VIb, VIc, VIIa, VIIb and VIII are encoded by the nuclear genome,...

Ngày tải lên : 20/02/2014, 23:20

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Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf

... with six ligands. The additional water occupied the postulated superoxide bind- ing site. The thermal stability of the enzyme was compared with superoxide dismutase from Thermus thermophilus, a thermophilic ... distribution of ApeSOD. The line reﬂects the best ﬁt of the data and indicates that the apparent molecular mass is 96 265 Da. The deviation between empirical data...

Ngày tải lên : 14/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... total sequencing and A. Burkowski for the plasmid pXMJ19. G. Auling and P. Stolle appreciate the help of J. Stubbe and J. Cotruvo with respect to improving the manuscript. The work was supported in part by the ... using the molecular mass of the R2F monomer, the absorption at 280 nm and protein quantiﬁcation, and is consistent with the theoretical e 280 . It should...

Ngày tải lên : 15/02/2014, 01:20

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Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx

... accompanied by the appear- ance and an increase in the 80 kDa fragment (Fig. 2). Although both the untransfected cells and the cells transfected with the vector alone started to show the 80 kDa fragment ... normal and cancerous cells [9], and ubiquitously distributed in the nucleolus, nucleus and cytoplasm of the cell, as well as at the cell surface [10]. Nucleolin...

Ngày tải lên : 16/02/2014, 09:20

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