Tài liệu Báo cáo khoa học: S100–annexin complexes – biology of conditional association doc

... 376 5–3 775. N. Miwa et al. Biology of S100–annexin complexes FEBS Journal 275 (2008) 494 5–4 955 ª 2008 The Authors Journal compilation ª 2008 FEBS 4955 REVIEW ARTICLE S100–annexin complexes – biology ... S100A10–annexin A2 complex (see above). Other S100–annexin complexes Although the number of reports is limited, other S10 0– annexin complexes have been rep...

Ngày tải lên: 18/02/2014, 14:20

... 204 3– 2046. S100–annexin complexes – structural insights A. C. Rintala-Dempsey et al. 4966 FEBS Journal 275 (2008) 495 6–4 966 ª 2008 The Authors Journal compilation ª 2008 FEBS REVIEW ARTICLE S100–annexin ... The large conformational change of helix III and the exposure of the hydrophobic resi- dues, first shown for S100B [3 6–3 8], have become a S100–annexin complexe...

Ngày tải lên: 18/02/2014, 14:20

... of parent node in dependency tree. c-word: word of child node. p-pos: POS of parent node. c-pos: POS of child node. p-pos+1: POS to the right of parent in sentence. p-pos-1: POS to the left of ... parent of x j . T = {(x t , y t )} T t=1 denotes the training data. We follow the edge based factorization method of Eisner (1996) and define the score of a dependency tree as the s...

Ngày tải lên: 20/02/2014, 15:20

... duality between the space of documents and the space of patterns: good extrac- tion patterns select documents relevant to the chosen scenario; conversely, relevant documents typically contain ... primary aim of the learning is to train a strong recognizer for ; is embodied in the set of good patterns. However, as a result of training , the procedure also produces the set of doc-...

Ngày tải lên: 20/02/2014, 16:20

... instance of this method based on identity of words in the variation contexts, so-called variation n-grams, successfully detects a variety of errors in the WSJ corpus. The usefulness of the notion of ... table reports the level of variation in the WSJ across identical contexts of different sizes. In the next section we turn to the issue of detecting those occurrences of a var...

Ngày tải lên: 22/02/2014, 02:20

... maximized when we rely on syntactic rules defined in terms of part -of- speech at the cost of a high degree of ambiguity. Thus, the goal of maximizing the parsing coverage while minimizing the ... results of the technique on the basis of two sets of unseen test data. In section 5 we discuss system engineering issues to accommodate the proposed technique, i.e., integration...

Ngày tải lên: 22/02/2014, 03:20

... internalized PCSK9–LDLR complexes. Effect of association time on the dissociation of [ 125 I]TC-PCSK9 The dependence of dissociation of [ 125 I]TC-PCSK9 and [ 125 I]TC-PCSK9-D374Y on the length of associa- tion ... determined by the rate of association. It should be noted that quanti- tative analysis of the more rapid phase of association requires measurement of the b...

Ngày tải lên: 14/02/2014, 14:20

... – – 0.444 ± 0.008 – – PhyP 5 PhyH-DI 120 0.523 ± 0.014 0.448 1.17 APPA 5 – – 1.978 ± 0.022 – – APPA 5 PhyH-DI 120 2.310 ± 0.004 1.982 1.20 PhyH 120 – – 3.260 ± 0.170 – – PhyH-DI ⁄ DII 120 – – ... yield Expected yield PhyH-DI 120 – – 0.004 ± 0.003 – – PhyH-DII 120 – – 0.302 ± 0.013 – – PhyH-DII 120 PhyH-DI 120 0.500 ± 0.026 0.31...

Ngày tải lên: 14/02/2014, 15:20

... because the off-rates are high (k off ‡ 0.2 s )1 ) [25]. A further way of describing macromolecular complexes is by the molecular interface of the interacting molecules. In common stable complexes ... contrast, interfaces of transient complexes are often not densely packed, and water can more easily gain access to the RNA–protein interface to increase the dissociation process. The...

Ngày tải lên: 14/02/2014, 19:20

... with a sulfone [R–S(O 2 )–R¢] [20], sulfonate ester [R–S(O 2 )–O–R¢] [21,22], sulfonamide [R–S(O 2 )–NH– R¢] [23], sulfamate [R–O–S(O 2 )–NH–R¢] [24], sulfamide [R–NH–S(O 2 )–NH–R¢] [25,26], and ... which phosphoryl [R–O–P(O 2 ) )–O–R¢] groups are replaced with N-acylsulfonamidyl [R–C(O)–N ) –S(O 2 )–R¢] or sulfonimidyl [R–S(O 2 )– N ) –S(O 2 )–R¢] groups increase the number of nonbridg...

Ngày tải lên: 14/02/2014, 22:20