... compilation ª 2009 FEBS An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori Naoki Okamoto1, Naoki Yamanaka2,*, Honoo Satake3, ... secreted in adevelopmentally regulated manner [4].ILPs are also found in insects [5,6]. Among these,bombyxins, a family of peptides produced by the brain of the silkmoth Bombyx mori, were the first ... than to those of bombyxin and insulin,which are of the order of 100 pm [23,24]. The veryhigh titer of 8K-BLP may be due to a remarkably highlevel of gene expression in the fat body and to the large...