Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

Tài liệu Báo cáo khoa học: Post-translational modifications of the linker histone variants and their association with cell mechanisms docx

... and function of the linker histone variants Location and structure of the linker histones Historically, the location of the globular domain of the linker histone has been a matter of contention ... number of these modifications is low, the density of modifications is much the same as in the rest of the lin- ker histones. It is the shortnes...
Ngày tải lên : 18/02/2014, 08:20
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Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

Tài liệu Báo cáo khoa học: An autoinhibitory effect of the homothorax domain of Meis2 ppt

... splicing. (B) The presence of alternative splicing around the 5¢-end of exon 6 of Meis2 and Meis3 was tested by RT-PCR. The positions of molecular mass markers are shown to the left, and the size ... independently of Pbx, and does not possess the autoinhibitory function of the Hth domain. In summary, our data suggest that one function of the conserved Hth d...
Ngày tải lên : 16/02/2014, 15:20
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Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf

Tài liệu Báo cáo khoa học: Protein kinase CK2 activates the atypical Rio1p kinase and promotes its cell-cycle phase-dependent degradation in yeast pdf

... relative to wild-type and arrest either as large G 1 cells (i.e. late in the G 1 phase of the cell- division cycle) or as large-budded M cells with a single DNA mass at the bud neck and short spindles. ... mass at the bud neck and the number of anaphase cells were increased slightly in the mutant (metaphase cells: 30.2% in the mutant versus 24% in the wild-type; a...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

Tài liệu Báo cáo khoa học: Substrate specificity of the pseudouridine synthase RluD in Escherichia coli doc

... obtained with the transition at posi- tions 1915 and 1917. These mutations had an effect on the formation of pseudouridine exclusively at the mutant position and did not affect either of the other two ... by Southern analysis. The rluD::cat strain had a full deletion of both rluD and yfiH, together with their annotated pro- moter sequences. The inserted cat casset...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

Tài liệu Báo cáo khoa học: Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen-related receptor c pptx

... environments of BPA in the ligand-binding pocket of the ERRc. The proximity of each amino acid residue (within a distance of 5 A ˚ ) to BPA is shown in the boxes depicting the a -heli- ces. The portrait ... (CH 2 ) of Glu at the c posi- tion. All these results indicate that the substitutions of Glu275 with Gln and Asp, and even with Ala, decrease considerab...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt

... to the right and the addition of further residues at the N-terminus or beyond residue 34 of the inhibitory segment is superfluous. However, in the case of PpPr, the serendipitous positioning of ... Thus, there is a need to under- stand the mechanisms of action of the few that are known, in order to exploit their therapeutic potential [1]. We have described pre...
Ngày tải lên : 19/02/2014, 00:20
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Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx

... that the variants undergo very fast optical (and thus structural) changes within the dead time of the stopped-flow apparatus. In the case of the K13N mutant, this hypo- thesis finds support from the ... Near-UV (A) and Soret (B) CD spectra of acid-denatured cytochrome c in the presence of 0.02 M sulfate (—) and 0.02 M sel- enate (— ÆÆ— ÆÆ). The spectra of the...
Ngày tải lên : 19/02/2014, 05:20
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Tài liệu Báo cáo khoa học: From heart to mind The urotensin II system and its evolving neurophysiological role ppt

Tài liệu Báo cáo khoa học: From heart to mind The urotensin II system and its evolving neurophysiological role ppt

... upstream region of the mature peptide. This raises the possibility of generating peptides of multiple lengths using atyp- ical processing. On the other hand, the active peptide of the URP precursor ... understand the extent of the UII system. The involvement of the UII system in sleep also points to a possible circadian regulation of the transcript and or pr...
Ngày tải lên : 19/02/2014, 07:20
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Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt

Tài liệu Báo cáo khoa học: Co-operative effect of the isoforms of type III antifreeze protein expressed in Notched-fin eelpout, Zoarces elongatus Kner ppt

... for the SP isoforms when the con- centrations of these isoforms was standardized to 1.0 mm. Significantly, the TH activity of the SP isoforms showed concentration dependence in the presence of ... the relationship between TH activity and the isoforms, especially the existence of a co-operative effect of the isoforms in the QAE and SP groups. We recently found...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

... in terms of the number of the enzymes involved, the kinetic mechanisms of the competing enzymes and the number as well as the nature of the allosteric controls. Whether such diversity in the organization ... independent of what happens on the cystathionine side. The Phser branch-point combines the divergence of two fluxes (fluxes of cystathionine and th...
Ngày tải lên : 20/02/2014, 02:21
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