Tài liệu Báo cáo khoa học: The endogenous retinoid metabolit

Tài liệu Báo cáo khoa học: The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro-retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo pdf

... compilation ª 2009 FEBS 3059 The endogenous retinoid metabolite S-4-oxo-9-cis-13,14-dihydro -retinoic acid activates retinoic acid receptor signalling both in vitro and in vivo Jan P. Schuchardt 1 , ... Identiﬁcation of 9,13-dicis -retinoic acid as a major plasma metabolite of 9-cis -retinoic acid and limited transfer of 9-cis -retinoic acid an...

Ngày tải lên : 18/02/2014, 08:20

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Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... which revealed that the BMPR-IA binding site of the related BMP-7 largely coincides with the noggin-binding area [32,42]. Thus, the proBMP-2 binding to noggin detected here indirectly conﬁrms the interaction ... speciﬁcally to the ECD of BMPR-IA. Furthermore, the results indicate that both proteins interact with the same epitope on the ECD because proBMP-2 binding can be i...

Ngày tải lên : 18/02/2014, 06:20

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Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efﬁciency doc

... of the res- idues involved in phosphate and calcium binding are conserved in the PhyH-DII sequence, whereas only one phosphate-binding residue is conserved in the PhyH-DI sequence (Fig. S1). There ... (Fig. 3A,B). The presence of Ca 2+ increased the thermal stability of PhyH and PhyH-DII. After incubation at 60 °C for 30 min, both enzymes retained > 70% of their initi...

Ngày tải lên : 14/02/2014, 15:20

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Tài liệu Báo cáo khoa học: The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases docx

... be involved in various signalling pathways, including blue light signalling [10] and auxin signalling [11–13]. The majority of group VIII AGC kinases are phosphorylated and activated by another AGC ... co-immunoprecipitation experiments. We then examined how both proteins interact with MPK3 and MPK6 proteins. Results AGC kinases interact with PTI1 kinases in vitro To iso...

Ngày tải lên : 14/02/2014, 19:20

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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf

... E2F4 ⁄ 5 and DP1 ⁄ 2 and a module containing the MuvB proteins Lin-37, Lin-52, Lin-54 and chromatin- associated Lin-9 and Lin-53 ⁄ RBBP4 ⁄ RbAp48. Furthermore, A-Myb and B-Myb were present in immunoprecipitations ... conﬁrmed by Lin-54 binding to the CHR, cooperating with E2F4 binding to the CDE in EMSAs in vitro [86]. ChIP experiments on the Cdc2 gene also provide...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The ubiquitin ligase Itch mediates the antiapoptotic activity of epidermal growth factor by promoting the ubiquitylation and degradation of the truncated C-terminal portion of Bid ppt

... [12]. Maintaining the balance between cell survival and apoptosis is critical in the maintenance of a healthy organism, and tipping the equilibrium in one or another direction results in either Keywords apoptosis; ... produced (Fig. 1D, lane 2). In the presence of lactacystin, a sig- niﬁcant increase in the amount of tBid–GFP present in the extract, both in con...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The plasminogen activator inhibitor 2 transcript is destabilized via a multi-component 3¢ UTR localized adenylate and uridylate-rich instability element in an analogous manner to cytokines and oncogenes pdf

... were 231 min for the b-globin PAI)2 wild-type transcript, 204 min f or the b-globin ARE I-MUT , 193 min for the b-globin ARE III-MUT and 224 min for the b-globin ARE I+III-MUT . These experiments ... or by northern analysis (10 lgof total RNA) using the intron spanning 32 P-labelled globin and GAPDH probes described above. The b-globin and GAPDH mRNA band intensities wer...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: The splicing factor ASF/SF2 is associated with TIA-1-related/ TIA-1-containing ribonucleoproteic complexes and contributes to post-transcriptional repression of gene expression doc

... speciﬁc interactions between cis-acting elements mainly localized in the UTRs of the transcript and the trans-acting factors (RNA-binding proteins and noncoding regulatory RNAs) that bind to these ... post-transcriptional regulation. Therefore, the results obtained in the present study support the recent ﬁndings showing that members of the SR proteins family, including...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: The two Caenorhabditis elegans metallothioneins (CeMT-1 and CeMT-2) discriminate between essential zinc and toxic cadmium docx

... expressed in vitro in the presence of either Zn(II) or Cd(II). Metal binding stoichiometries and afﬁnities were determined by ESI-MS and NMR, respectively. Both isoforms had equal zinc binding ability, ... to the wild-type strain. Both CeMT-1 and CeMT-2 are important in maintaining physiological zinc levels Under control (non-metal-supplemented) conditions in the wil...

Ngày tải lên : 16/02/2014, 15:20

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Tài liệu Báo cáo khoa học: The multicopper oxidase from the archaeon Pyrobaculum aerophilum shows nitrous oxide reductase activity docx

... (Fig. 1). The MCO sequence motif pattern, which contains the four elements that together form the copper-binding sites in the protein, is conserved in McoP, including a Met corresponding to the axial ... rapid and sensitive method for the quantiﬁcation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72, 248–254. Supporting in...

Ngày tải lên : 18/02/2014, 04:20

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