Tài liệu Báo cáo khoa học: Restricted localization of prolin

Tài liệu Báo cáo khoa học: Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions – contribution and expression from motor neurons doc

... FEBS Restricted localization of proline-rich membrane anchor (PRiMA) of globular form acetylcholinesterase at the neuromuscular junctions – contribution and expression from motor neurons K. Wing Leung, ... investigate the contribution of the motor neuron to PRiMA-linked G 4 AChE at NMJs, we analyzed the effect of denervation on...

Ngày tải lên : 18/02/2014, 08:20

12
488
0

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... we focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and treatment of these conditions. Suppression ... grant from the Takeda Science Foundation, by a grant from the Sumitomo Foundation, by a grant from the Mitsubishi Foundation, and by a grant from...

Ngày tải lên : 14/02/2014, 22:20

6
609
0

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... is composed of residues from the SET-I region and the other of residues from the SET-C and post-SET regions. Lysine 4 of histone H3 is inserted into a chan- nel, at the end of which is the AdoHcy ... mechanism of multiple lysine methylation is dis- tinct from that expected from a conformational change in the SET domain active site [35]. To test the altern...

Ngày tải lên : 16/02/2014, 14:20

11
761
0

Tài liệu Báo cáo khoa học: Bacitracin is not a speciﬁc inhibitor of protein disulﬁde isomerase pptx

... [21], the aggregation of Cu ⁄ Zn superoxide dismutase in motor neurons [22], the operation of the vitamin K cycle [23], protection against stroke [24] and thrombus formation [25], and the functions ... effects, the ﬂuo- rescence of the peptide is quenched, and it contributes a smaller proportion of the total ﬂuorescence of the system. However, in the pres...

Ngày tải lên : 16/02/2014, 14:20

9
620
0

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... [38]. Therefore, the metal swap led to simultaneous modification of the final form of Ab( 1–4 0) and suggests that it caused the de-aggregation of Ab. In a therapeutic context, this indicates that MT ... in the AD brain. There remains no clear con- sensus on the role of GIF in the pathogenesis of AD, and therefore we will briefly review some of the current thoug...

Ngày tải lên : 16/02/2014, 15:20

9
664
0

Tài liệu Báo cáo khoa học: Catabolite repression in Escherichia coli – a comparison of modelling approaches docx

... must be paid to the mathematical correctness of the model, the inclusion of relevant biological knowledge and quantitative (and mostly iterative) validation of the model. The model of Nishio et ... like the break down of substrates, the generation of energy in form of ATP, or the syn- thesis of amino acids. Based on this more fuzzy deﬁni- tion, the ide...

Ngày tải lên : 18/02/2014, 13:20

9
723
0

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... Altogether, these data support a model whereby insulin stimulates the recruitment of endogenous Grb14 to the activated IR at the plasma membrane, and induces internalization of the Grb14–IR com- plex ... together, these data strongly suggest that the phosphorylation status of IRb is implicated in the in vivo association of Grb14 with IR-containing subcel- lular compar...

Ngày tải lên : 18/02/2014, 18:20

15
497
0

Tài liệu Báo cáo khoa học: DNA adenine methylation changes dramatically during establishment of symbiosis pdf

... unmethylated GATC sites and that all of them are located in the 5¢ noncoding AB Fig. 4. DNA methylation status before and after establishing symbiosis. (A) Hybridization pattern of ARM-AH1-B07. The ... development and digitization. These results suggest that the bacter- ial DNA adenine methylation status changes during the establishment of the symbiotic relationship and...

Ngày tải lên : 19/02/2014, 02:20

12
433
0

Tài liệu Báo cáo khoa học: Peptides corresponding to helices 5 and 6 of Bax can independently form large lipid pores pdf

... negative curvature strain. However, it is difficult to separate the influence of curvature from that of the net negative charge of the lipid, which may inhibit pore formation through alter- native ... molecules. At the rim of the membrane hole, the two leaflets of the bilayer can make contact with each other, forming a membrane edge with positive mono- layer curva...

Ngày tải lên : 19/02/2014, 07:20

11
586
0

Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf

... pyroglutamyl formation to the conformational stability of active onconase In order to evaluate the contribution of the (Met1) hydrolysis and pyroglutamyl formation to the global conformational stability of ... almost linear and can be obtained by calculating the slope of the curves of Pyr-ONC (M23L) vs. time. From the rates of cyclizationshowninTable1,itcanbe...

Ngày tải lên : 19/02/2014, 12:20

9
704
0