Tài liệu Báo cáo khoa học: The cartilage-specific transcription factor Sox9 regulates AP-2e expression in chondrocytes pptx

... replace the tri-glycine segment in the envelope targeting sequence. Thus, mtHsp70-like protein may not be involved in the polyglycine-mediated envelope targeting. In order to test the second hypothesis, ... that the most C-terminal tri-glycine within the polyglycine stretch is important for correctly targeting the protein to the outer membrane. Interest- ingly, replaceme...

Ngày tải lên: 19/02/2014, 07:20

... result, the instruction did not match the initial essay quality. Nonetheless, in the open- question interviews, many users indicated using the NM as a reference while updating their essay. In addition ... perception of the system in terms of their ability to concen- trate on the instruction (Q3), in terms of their incli- nation to reuse the system (Q6) and in terms of...

Ngày tải lên: 20/02/2014, 12:20

... cobalamins (2.9–5.1°) [9,10]. Figure 4C indicates the comparison of the position of the a-acetamide side chain of pyrrole ring A of the corrin ring in the glycerol dehydratase-bound cobalamin (Fig. ... bulk of water by the corrin ring of cobalamin. Figure 4B shows the structure around the enzyme-bound cobalamin. The cobalamin molecule is bound between the a and b subunit...

Ngày tải lên: 21/02/2014, 03:20

... attempt to find evidence linking the dialogue structure to the task structure. The main point is that the structure of the intentions conveyed in the discourse should mirror to some extent the task ... at the beginning of the subdialogues than later in the subdialogues. On the other hand, pronominal noun phrases are used to refer to entities currently in focus....

Ngày tải lên: 21/02/2014, 20:20

... We focus on the function and relationship of the two single domains. Additionally, the possibility that fusion of the PhyH N-terminal domain to other single-domain BPPs would improve the catalytic ... of the res- idues involved in phosphate and calcium binding are conserved in the PhyH-DII sequence, whereas only one phosphate-binding residue is conserved in the PhyH-DI s...

Ngày tải lên: 14/02/2014, 15:20

... alone. The kinase-deficient mutant, OXI1 K45R , in which the lysine residue of the ATP bind- ing domain is mutated to arginine, still interacted with PTI1-4. These data indicate that the kinase ... of the input was loaded on to the gel and represents the amount of HIS-tagged proteins used for the assay. The in vitro binding assays were repeated twice using recombinant pro...

Ngày tải lên: 14/02/2014, 19:20

... confirmed by Lin-54 bind- ing to the CHR, cooperating with E2F4 binding to the CDE in EMSAs in vitro [86]. ChIP experiments on the Cdc2 gene also provided insights into the association of other cell ... proteins with the promoter. E2F4 binding during the cell cycle coincides with the binding of p107 or p130 [61,85]. Another E2F site distal to the E2F ⁄ CDE acts as an activa...

Ngày tải lên: 16/02/2014, 09:20

... critical in the maintenance of a healthy organism, and tipping the equilibrium in one or another direction results in either Keywords apoptosis; Bid; c-Jun N-terminal kinase; epidermal growth factor; ... through the mitochondrial pathway. The key event in the mito- chondrial pathway is the release of proapoptotic fac- tors from the mitochondrial intermembrane space into...

Ngày tải lên: 16/02/2014, 09:20

... were 231 min for the b-globin PAI)2 wild-type transcript, 204 min f or the b-globin ARE I-MUT , 193 min for the b-globin ARE III-MUT and 224 min for the b-globin ARE I+III-MUT . These experiments ... investigate the means by which these ARE elements cooperate in modulating PAI-2 mRNA stability, REMSA analyses were performed to determine the role of the ARE II and ARE IV si...

Ngày tải lên: 16/02/2014, 09:20

... nuclear in normal cells, the splicing factor ASF ⁄ SF2 relocalized into the cytoplasm in response to stress and accumulated in bona fide SGs. Furthermore, the results obtained in the present study indicate ... post-transcriptional regulation. Therefore, the results obtained in the pres- ent study support the recent findings showing that members of the SR proteins fam...

Ngày tải lên: 16/02/2014, 15:20