Tài liệu Báo cáo khoa học: Reaction mechanisms of thiamin diphosphate enzymes: redox reactions pdf

... Redox reactions of thiamin diphosphate enzymes FEBS Journal 276 (2009) 2454–2468 ª 2009 The Author Journal compilation ª 2009 FEBS 2463 kinetic investigations of the reductive half -reaction of LpPOX ... 2454–2468 ª 2009 The Author Journal compilation ª 2009 FEBS MINIREVIEW Reaction mechanisms of thiamin diphosphate enzymes: redox reactions Kai Tittmann Albrecht...

Ngày tải lên: 18/02/2014, 08:20

... Journal compilation ª 2009 FEBS MINIREVIEW Reaction mechanisms of thiamin diphosphate enzymes: defining states of ionization and tautomerization of the cofactor at individual steps Natalia S. Nemeria, ... pH dependence of the amplitude of the band for the AP form of ThDP. Determination of pK a for the ([AP]+[IP]) ⁄ [APH + ] equilibrium on BAL [45]. Table 1. Assignment...

Ngày tải lên: 29/03/2014, 23:20

... of ingested pathogen Release of digested material by exocytosis Fig. 1. Detailed structure of a macrophage showing a typical process of phagocytosis. Phagosome Lysosome Inhibition of fusion of ... candidates for the treatment of the disease. A variety of mechanisms have been suggested to con- tribute towards the survival of Mycobacterium within macrophages. These mechanis...

Ngày tải lên: 16/02/2014, 15:20

... Classification of Medical Assertions in Clinical Notes Youngjun Kim Ellen Riloff Stéphane M. Meystre School of Computing School of Computing Department of Biomedical Informatics University of ... to measure the impact of each of the four subsets of features explained in Section 3. Ta- ble 3 shows the cross validation results when cu- mulatively adding each set of...

Ngày tải lên: 20/02/2014, 05:20

... Methods PoStag In the first of these, we constructed a rough approximation of typical sentence grammar structure by taking bigrams over part -of- speech tags. 6 Then, given a string of PoS tags of length n, t 1 . ... magnitude of the first three parser metrics, however, lends support to the idea of Wan et al. (2005) to use something like these as indicators of generated sentence fl...

Ngày tải lên: 20/02/2014, 12:20

... (Synergy Software, Reading, PA, USA). The final concentration of the radiolabeled substrate in all reactions is 1.3 nm. A typical reaction utilized H10Mg buffer and a final ribozyme concentration of 166 ... constant of the 5¢ exon mimic, h is the fraction of 5¢ exon mimic bound to the ribozyme, and [ribozyme] u is the concentration of unbound ribozyme in the reaction. Measuremen...

Ngày tải lên: 18/02/2014, 18:20

... move- ment of the cofactor-binding domain of subunit A rela- tive to subunits B and C (not shown). This domain alteration involves a rotation of 5° and translation of 0.7 A ˚ . Five segments of polypeptide ... comparing the cofactor domains of the OaPDH and TbPDH structures [13]. The superposition of sub- unit A of complex I onto subunits A, B, C of complex II and III yield...

Ngày tải lên: 19/02/2014, 05:20

... monitored t he internalization of the Tat peptide by ¯ow cytometry analysis (Fig. 2), a technique allowing the evaluation of the homogeneity of the cellular population i n terms of uptake e f®ciency. ... [9]. However a rightward shift of the s ignal was observed signifying a reduction of the uptake of the Tat peptide at low temperature. Likewise, a threefold r eduction of the...

Ngày tải lên: 21/02/2014, 03:20

... shikimate pathway that leads to the biosynthesis of aromatic amino acids, and the mode of action of glyphosate on the reaction catalyzed by EPSPS. Mechanisms of glyphosate resistance L. Pollegioni et ... 4% of the total soluble protein content of the cell [48]. Fig. 3. Microbial mechanisms of glyphosate degradation. (A) Two principal pathways of glyphosate degradation ar...

Ngày tải lên: 14/02/2014, 14:20

... of tau with Fyn-SH3. We also show that tau interacts with the SH2 domain of Fyn, and that this associa- tion, unlike that of Fyn-SH3, is influenced by Fyn-mediated tyrosine phos- phorylation of ... SH3 domain of Fyn binds to proline-rich motifs within the sequence PXXP in interacting pro- teins. Seven such motifs are present in the proline-rich domain of the longest isoform of ta...

Ngày tải lên: 14/02/2014, 14:20