Tài liệu Báo cáo khoa học: The pro-form of BMP-2 interferes with BMP-2 signalling by competing with BMP-2 for IA receptor binding pptx

... analyses Partial sequences were assembled with genedoc 2.7 [41]. The tools provided with the ExPASy Molecular Biology Server of the Swiss Institute of Bioinformatics (http:// www.expasy.org) were used for ... mediated by the tracheal system, a network of tubules that open to the atmosphere on the cuticle and radiate to all parts of the body. O 2 is delivered thro...

Ngày tải lên: 18/02/2014, 08:20

... calculated from the standard errors associated with the means of the measured values (i.e. by calculating the square root of the sum of the associated individual errors squared). The maximum percentage ... aB-crystallin (i.e. the effect of the additive on the aggregation of the target protein is inde- pendent and different from that of the chaperone)....

Ngày tải lên: 18/02/2014, 16:20

... They observed two helical arrays: one for repeat lengths below 210 bp with a diameter of 33 nm and another for repeat lengths above 210 bp with a diameter of 45 nm and with the flat surfaces of ... structures presented by the two groups for the 177 bp as well as the 207 and 208 bp repeat lengths, which differ by the presence ⁄ absence of the linker histone....

Ngày tải lên: 18/02/2014, 18:20

... associated with the intercalative conformation of the (+)-cis adduct and the minor- groove conformation of the (+)-trans adduct, the lat- ter interfering with interactions of the catalytic loops of ... that the stereoisomeric (+)-cis-B[a]P-N 2 -dG lesion has only a minimal effect on the binding of these MTases and on k cat . The minor-groove (+)-trans adduct...

Ngày tải lên: 19/02/2014, 00:20

... pointed to a role for components of the ER–Golgi vesicle transport. Through the use of mark- ers for the ER (PDI) and the Golgi apparatus (GM130, p230), the phosphorylated isoforms of the K650M mutant ... charac- terized by a variable but marked reduction in the fully glycosylated isoform and a significant increase in the nonglycosylated and partially glycosylated i...

Ngày tải lên: 19/02/2014, 00:20

... perpendicular to the center of the membrane (Fig. 4); (b) the major axis of the dimeric RNase was made coinci- dent with the z axis of the system, hence orthogonal to the membrane plane (Fig. 4); (c) the ... negligible contribution of the protein to the degree of polarization of the fluorescence probe. Leakage of vesicle aqueous contents induced by the...

Ngày tải lên: 19/02/2014, 06:20

... fusion with the membrane of intra-endosomal vesicles contained within MVBs, thereby releasing the nucleocapsid into the lumen of these vesi- cles. Then, the capsid uses these intra-endosomal vesicles ... function of the oncogene Fos as a potential tumor suppres- sor. Recent data regarding the target genes of Fos in OS and RMS cells obtained by microarray analyses will...

Ngày tải lên: 19/02/2014, 07:20

... Table 1. Assay of the N -glycosidase activity of ricin A chain variants The activity of each of the RTA variants was determined by assessing their ability to depurinate 26S rRNA of Table 1. Data ... reduced by 20-fold more than the catalytic activity of RTA R213D. The X-ray structure of RTA R213D In the absence of structural data for each of the RTA varia...

Ngày tải lên: 19/02/2014, 12:20

... proteins akin to the lysozyme i type. We performed a phylogenetic analysis of all of these sequences together with those of the more conventional lysozyme c type; the results suggested that these two ... previous work [10], with the lysozyme of the bivalve Tapes japonica [3], with the so-called chlamysin of Chlamys islandica [4,5], and also with a hypothetical se...

Ngày tải lên: 19/02/2014, 12:20

... and the effect of the absence of intact complex I, but the results are too preliminary in this regard. Heterologous expression of the ESSS-HA subunit The localization of the ESSS subunit in the ... truncated at the C-terminus of the targeting sequence; the m utants are null mutants for the ESSS subunit. There is no detectable complex I assembly and a ctivity...

Ngày tải lên: 19/02/2014, 16:20