Tài liệu Báo cáo khoa học: The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly doc

... independent proteins and peptides leads to the disassembly of the spherical capsid inside the virion. Some of the folded domains of Gag are then able to reassemble as inde- pendent proteins. The matrix protein ... diverse CA–CA interactions and inter- faces involved either in the assembly of the immature HIV-1 capsid, or in the reassembly of CA into a mature...

Ngày tải lên: 18/02/2014, 06:20

... on the capsid protein of the human immunodeficiency virus type 1: a new drug target? Sci World J 9, 404–419. 6 Mateu MG (2009) The capsid protein of human immu- nodeficiency virus: intersubunit interactions ... 2009) doi:10.1111/j.1742-4658.2009.07314.x The mature capsid of human immunodeficiency virus, HIV-1, is formed by the assembly of copies...

Ngày tải lên: 18/02/2014, 06:20

... of HIV-1 capsid FEBS Journal 276 (2009) 6118–6127 ª 2009 The Authors Journal compilation ª 2009 FEBS 6127 MINIREVIEW The capsid protein of human immunodeficiency virus: interactions of HIV-1 capsid ... 2009) doi:10.1111/j.1742-4658.2009.07315.x HIV-1 is a retrovirus that causes AIDS in humans. The RNA genome of the virus encodes a Gag polyprotein, which is fu...

Ngày tải lên: 07/03/2014, 00:20

... present for the last four residues at the C-terminus. The stereochemistry of the model has been assessed using the program procheck [23]. Ninety per cent of the residues fall in the most favoured regions ... movement of the two protein residues upon ligand binding. The dotted line highlights the hydrogen bond established between the DHAP phosphate moiety and Trp1...

Ngày tải lên: 18/02/2014, 06:20

... properties of the minor structural proteins (VP2 and VP3) of the MPyV were studied in the absence of other virus components as well as during the late phase of virus infection. The role of the minor ... levels of apoptotic markers during the late stages of MPyV infection. However, comparison of the levels of apoptotic markers and cytotoxicity during...

Ngày tải lên: 16/02/2014, 09:20

... forms of the MAPKs were produced as GST-lofMPK3 and GST- lofMPK6. However, when lofMPK3 and lofMPK6 proteins were tested for phosphorylation with OXI1, no phosphorylation of lofMPK3 or lofMPK6 ... [17]. On the other hand, expression of the tomato SlPti1 cDNA in the rice Ospti1a mutant suppressed the mutant phenotype. These results indicate that PTI1 acts as a negative reg- ula...

Ngày tải lên: 14/02/2014, 19:20

... yielded deregulation, which was dependent on the CDE of the human Cdc25C promoter. Dimethyl sulfate footprint- ing of the CDE in the presence of SV40 large T indi- cated a loss of protein occupation on this site ... footprinting. Loss of the two pocket proteins leads to deregulation of the B-Myb promoter during the cell cycle. Re-intro- duction of p107, and t...

Ngày tải lên: 16/02/2014, 09:20

... biological function of the pro-form of bone morphogenetic protein- 2 (BMP-2), a member of the transforming growth factor b (TGFb) ⁄ BLP superfamily. The role of the 263 amino acids of the pro-peptide ... Furthermore, the pro-peptide of GDF-8 impairs interaction of the mature part with its receptors [16]. In the case of BMP-9, the pro-pep- tide appears not to...

Ngày tải lên: 18/02/2014, 06:20

... [10]. Although the occurrence of family 33 CBPs has been known for some time [23], the present results provide only the third demonstration of the accessory function of these proteins. The effect of LlCBP33A ... putatively encoding these proteins occur in many microorganisms. To obtain an impression of the functional conservation of these proteins, we studied the chi...

Ngày tải lên: 18/02/2014, 08:20

... membrane-spanning proteins in protein protein interactions has also been proved, e.g. the case of the association between the N-terminal region of the membrane-bound tyrosine kinase Lck with the cytoplasmic ... that most of the RIP substrates, including Jagged-1, actu- ally fall in the left-hand side of the plot (natively unfolded proteins). All the proteins that...

Ngày tải lên: 18/02/2014, 16:20