Tài liệu Báo cáo khoa học: Resolving the native conformation ofEscherichia coli OmpA docx

Tài liệu Báo cáo khoa học: Resolving the native conformation ofEscherichia coli OmpA docx

Tài liệu Báo cáo khoa học: Resolving the native conformation ofEscherichia coli OmpA docx

... between the M -OmpA and I -OmpA structures, and imply that critical modifica- tion(s) of OmpA occur in the periplasm. The effect of cOHB-modification of the C-terminal domain in the periplasm on the ... essen- tial for the transition of the narrow-pore to the large- pore conformation, but is not necessary for retention of the large-pore conformation. The effect of ur...
Ngày tải lên : 18/02/2014, 04:20
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Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx

Tài liệu Báo cáo khoa học: Seeking the determinants of the elusive functions of Sco proteins pptx

... mitochondrial matrix, the transmembrane helix and the following  20 residues) is crucial to determin- ing the aggregation state of these proteins. The data therefore support the hypothesis that this ... close to the N-terminal trans- membrane helix anchoring the protein to the inner membrane of mitochondria [27]. Therefore, the N-ter- minal segment (containing the residue...
Ngày tải lên : 14/02/2014, 18:20
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Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf

Tài liệu Báo cáo khoa học: Understanding the binding properties of an unusual metal-binding protein ) a study of bacterial frataxin pdf

... in the refinement. The correctness of the model was checked using the procheck [43] and whatcheck [44] programs. The coordinates of the higher-resolution complex models have been deposited in the ... between the free and the bound forms. In the latter case, the line broadening caused by the dynamic process could be extremely large and unspecific, preventing the detecti...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis docx

Tài liệu Báo cáo khoa học: Probing the molecular determinants of aniline dioxygenase substrate specificity by saturation mutagenesis docx

... using the T4 DNA ligase. The salts from the ligation reactions were then removed by precipitating the ligated DNA with n-butanol [46]. The ligation products were then transformed into E. coli ... may indicate that the steric limitation of the enzyme’s binding pocket takes place in the area between the ortho and para positions of the aromatic substrate. On the basis of...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx

Tài liệu Báo cáo khoa học: Glucuronate, the precursor of vitamin C, is directly formed from UDP-glucuronate in liver pptx

... indicated, the assay was initiated by the addition of the enzyme preparation to an otherwise complete assay mixture. The reaction was stopped after 0–30 min by mix- ing a portion of the incubation ... glucuronate 1-phosphate [5,6]. However, neither the pyrophospha- tase nor the phosphatase implicated in these reactions has been identified. Furthermore, other mechanisms, in which...
Ngày tải lên : 19/02/2014, 07:20
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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc

... dehydrogenase, which weremeasuredtogetherinthesameassay.Thedataindicate that the p resence of propionate in the medium reduces the activity by % 50% in the w ild-type as well a s in the DmcsA strain. T herefore ... in Escherichia coli the 2-oxo acid is further oxidized to acetyl-CoA, which is either funnelled i nto the citrate cycle or used for biosyntheses [7]. A clue to the...
Ngày tải lên : 19/02/2014, 16:20
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Tài liệu Báo cáo khoa học: "Modeling the Translation of Predicate-Argument Structure for SMT" ppt

Tài liệu Báo cáo khoa học: "Modeling the Translation of Predicate-Argument Structure for SMT" ppt

... semantic role of the argument, the head word and the boundary words of the argument. On the target side, the trans- lation of the verbal predicate, the translation of the head word of the argument, ... shows the features that are used in the argument reordering model. We extract features from both the source and target side. On the source side, the fea- tures inc...
Ngày tải lên : 19/02/2014, 19:20
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Tài liệu Báo cáo khoa học: "Learning the Latent Semantics of a Concept from its Definition" pptx

Tài liệu Báo cáo khoa học: "Learning the Latent Semantics of a Concept from its Definition" pptx

... are highly related to the observed words. Therefore, missing words can be used to prune the hypotheses that are also highly related to the missing words. Consider the hypotheses of latent vectors ... Semcor. We tune the parameters in wmfvec and other base- lines based on SE2, and then directly apply the tuned models on other three data sets. Data: The sense inventory is WN3.0 fo...
Ngày tải lên : 19/02/2014, 19:20
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Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx

Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx

... spanned either the second quarter of the TC sequence GQLA…TAAM(103–198) or the C-ter- minal peptide LEPA…LVSW(316–427). Proteolytic fragments of TC and the synthetic peptides were used to further ... with the peptides identified by N-terminal sequencing. The left sketch depicts the frag- ments aligned and in accordance with their relative length. The theoretical molecular masse...
Ngày tải lên : 20/02/2014, 01:20
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