Tài liệu Báo cáo khoa học: Paradoxical interactions between modifiers and elastase-2 Patricia Schenker and Antonio Baici docx

Tài liệu Báo cáo khoa học: Paradoxical interactions between modifiers and elastase-2 Patricia Schenker and Antonio Baici docx

Tài liệu Báo cáo khoa học: Paradoxical interactions between modifiers and elastase-2 Patricia Schenker and Antonio Baici docx

... Schenker and A. Baici Interactions between modifiers and elastase-2 FEBS Journal 277 (2010) 2486–2495 ª 2010 The Authors Journal compilation ª 2010 FEBS 2495 Paradoxical interactions between modifiers ... interactions between modifiers and elastase-2 Patricia Schenker and Antonio Baici Department of Biochemistry, University of Zurich, Switzerland Intro...

Ngày tải lên: 16/02/2014, 14:20

10 589 0
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx

... ANGPTL2 and ANGPTL6 ⁄ AGF in obesity and related metabolic diseases, and discuss the possibility that both could func- tion as molecular targets for the prevention and treatment of obesity and metabolic ... focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes- ity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and tre...

Ngày tải lên: 14/02/2014, 22:20

6 610 0
Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

Tài liệu Báo cáo khoa học: Erythrochelin – a hydroxamate-type siderophore predicted from the genome of Saccharopolyspora erythraea docx

... with an inverse broadband probe installed with z-gradient. The 1D spectra 1 H and 13 C; the homonuclear 2D spectra DQF-COSY, TOCSY, NOESY and ROESY; the 1 H– 3 C HSQC and HMBC; and the 1 H– 15 N ... connection between the terminal ac-haOrn 1 and the Ser 2 , whereas the other two were for a sequential connection between a d-N-hydroxyornithine and a d-N-acetyl-d-N-hydroxyornithi...

Ngày tải lên: 16/02/2014, 09:20

14 614 0
Tài liệu Báo cáo khoa học: Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer–fluorescence lifetime imaging microscopy in living cells doc

Tài liệu Báo cáo khoa học: Loose interaction between glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase revealed by fluorescence resonance energy transfer–fluorescence lifetime imaging microscopy in living cells doc

... The distances between the N- terminal amino acids of subunits O and P, subunits O and Q and subunits O and R are shown (B–D). FLIM analysis of the interaction between cerulean–GAPDH and citrine–GAPDH ... glycolytic and glu- coneogenic pathways, pairs of enzymes – aldolase and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), GAPDH and phosphoglycerate kinase (PGK), GAP- DH...

Ngày tải lên: 16/02/2014, 09:20

9 586 0
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in gene expression, hormone signaling and mRNA processing docx

... regulation and mixed lineage leukemia. Acknowledgements We thank Imran Hussain, Sahba Kasiri, Bishakha Shrestha, Saoni Mandal and other Mandal lab mem- bers for useful discussion and critical ... DNA-binding domain, a ligand-binding domain and a transactivation domain. The DNA-bind- ing domain is responsible for DNA binding specificity and dimerization, and the ligand-binding domai...

Ngày tải lên: 16/02/2014, 14:20

15 607 0
Tài liệu Báo cáo khoa học: Anaerobic sulfatase-maturating enzyme – A mechanistic link with glycyl radical-activating enzymes? docx

Tài liệu Báo cáo khoa học: Anaerobic sulfatase-maturating enzyme – A mechanistic link with glycyl radical-activating enzymes? docx

... electron transfer and ⁄ or binding and activating the peptidyl substrates. Experimental procedures Chemicals All chemicals and reagents were obtained from commercial sources and were of analytical ... AdoMet was synthe- sized enzymatically and purified as described previously [17]. anSMEcpe and anSMEbt protein expression and purification Protein expression and purification were p...

Ngày tải lên: 16/02/2014, 14:20

15 560 0
Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx

Tài liệu Báo cáo khoa học: Comparison of membrane fraction proteomic profiles of normal and cancerous human colorectal tissues with gel-assisted digestion and iTRAQ labeling mass spectrometry pptx

... total of eight tumor tissues and eight matched normal tissues were collected from eight CRC patients (Table S1) and protein expression was compared between each tumor and adjacent normal tissue ... We used solvent extraction and a gel-assisted digestion method, together with isobaric tags with related and absolute quantitation (iTRAQ) reagents to label tumoral and adjacent norma...

Ngày tải lên: 16/02/2014, 15:20

11 590 0
Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx

Tài liệu Báo cáo khoa học: Modulation of sterol homeostasis by the Cdc42p effectors Cla4p and Ste20p in the yeast Saccharomyces cerevisiae pptx

... Erg4p, Cbr1p and Ncp1p, which are all involved in sterol biosynthesis [25]. We also observed genetic inter- actions between PAKs and ERG4 as well as between PAKs and NCP1. Both ERG4 and NCP1 are ... sterols for cell polarization, and the interactions between PAKs and proteins catalyzing sterol synthesis and storage, it is tempting to speculate that Ste20p and Cla4p may...

Ngày tải lên: 18/02/2014, 13:20

12 699 0
Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt

Tài liệu Báo cáo khoa học: A knowledge-based potential function predicts the specificity and relative binding energy of RNA-binding proteins ppt

... structure. Some RRM and KH domains in complex with single strand DNA (PDB codes: 2UP1, 1WTB, 1X0F, 1ZZI and 1ZZJ) were also included in the test set because recognition of single stranded RNA and DNA are ... Fox-1 protein. (B) The intramolecular hydrogen bond between uracil 1 and cytosine 3, and the non-Wat- son–Crick base pair between guanine 2 and adenine 4 for the RNA in co...

Ngày tải lên: 18/02/2014, 16:20

14 736 0
Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc

Tài liệu Báo cáo khoa học: Branched N-glycans regulate the biological functions of integrins and cadherins doc

... membrane and mediate interactions with the cytoskeleton and with signaling molecules. On the basis of extensive searches of the human and mouse genomic sequences, it is now known that 18 a-subunits and ... migration and signal transduction. Collectively, N-glycans on adhesion molecules, especially those on E-cadherin and integrins, play key roles in cell–cell and cell–extracel...

Ngày tải lên: 18/02/2014, 17:20

10 477 0
w