Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf

... Cork, Ireland (Received 16 February 2 010 , revised 19 March 2 010 , accepted 23 March 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .076 61. x Activation of the c-JUN N-terminal kinase (JNK) pathway is implicated ... c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis Ulla Sc...

Ngày tải lên: 16/02/2014, 14:20

... (residues 1 299) SAIL At3g16450 .1. (B) Overlay of 1 H- 15 N HSQC spectra of the N-terminal (residues 1 15 3, blue) and C-terminal (residues 15 1–299, red) halves of [U- 15 N]-labeled At3g16450 .1. These ... no. 210 .1) N-glycan Galb1-4GlcNAcb1-2Mana1-6 (Galb1-4GlcNAcb1-2 Mana1-3)Manb1-4GlcNAcb1-4(Fuca1-6) GlcNAc (code no. 210 .4) N-glycan GlcNAcb1-2Mana1-6(GlcNAcb1-2Man...

Ngày tải lên: 18/02/2014, 14:20

... + 81 29 853 4490 Tel: + 81 29 853 5600 (5466) E-mail: yokokawa@ims.tsukuba.ac.jp (Received 9 March 2 011 , revised 24 May 2 011 , accepted 16 June 2 011 ) doi :10 .11 11/ j .17 42-4658.2 011 .08222.x Studies of ... events, and k 1 is the rate constant. The obtained rate constants (k 1 ) were 0 .15 ms )1 at 10 nm ATP and 0 .17 ms )1 at 10 0 lm Fig. 2. Histograms of...

Ngày tải lên: 14/02/2014, 14:20

... (2 011 ) 11 90 12 02 ª 2 011 The Authors Journal compilation ª 2 011 FEBS VirB5 then forms a complex with VirB2, which is a key step in the formation of the T4SS pilus assembly subcomplex. A model for ... ª 2 011 FEBS 11 93 Type IV secretion in H. pylori pathogenesis N. Tegtmeyer et al. 11 94 FEBS Journal 278 (2 011 ) 11 90 12 02 ª 2 011 The Authors Journal compilation ª 2 0...

Ngày tải lên: 14/02/2014, 19:20

... Epac and the small GTPase Rac [11 1 ,11 2]. This recently led to synthesis and evaluation of novel 5-HT4-agonists; two of them increased APPs-a production in the cortex and hippocampus of mice and ... January 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .07566.x A decade ago, a disintegrin and metalloproteinase 10 (ADAM10) was iden- tified as an a-secretase and as a key p...

Ngày tải lên: 16/02/2014, 09:20

... July 2 010 , accepted 11 August 2 010 ) doi :10 .11 11/ j .17 42-4658.2 010 .07828.x Regulation of gene expression is fundamental in all living organisms and is facilitated by transcription factors, the single ... activity of HSF1 and HSF2 is needed for normal spermatogenesis and male fertility [11 5]. The finding that HSF1 and HSF2 physically interact in lysates of...

Ngày tải lên: 18/02/2014, 04:20

... -2, -3, -10 , and -11 relative to the cleavage site. The leader sequence inter- acts with the TOM receptor, responsible for the trans- location of the preproteins to the translocase of the inner ... ATP concentration for 10 min at 30 °C with 0.5 l M of purified protein. MDL1 (A) and MDL1(60-695) (B) showed Michaelis– Menten kinetics with a K m ATP of 12 0 ± 6 l...

Ngày tải lên: 18/02/2014, 16:20

... observed. The other two components of the nuage, Nanos and Tudor, exhibit diffusion constants of 1. 7 0 0.2 0.4 0.6 0.8 1 1.2 0 10 203040 0 0.2 0.4 0.6 0.8 1 1.2 1. 4 A B 1 10 10 0 10 00 10 000 10 0 000 Time ... together and apart in this time scale. Arrowheads show the assembly and dissociation points. 0 0.2 0.4 0.6 0.8 1 1.2 0 5 10 15 20 0 0.4 0.8 1. 2 1....

Ngày tải lên: 18/02/2014, 16:20

... Bacterial 15 .00 3.60 1fdr [10 ] a Angle formed between the tyrosine and the re-face of isoalloxa- zine, measured as shown in Fig. 2A. b Distance (d ) from the center of the phenol ring to the center of ... coplanar to the re-face of the isoalloxazine moiety and interacts extensively with it (Fig. 1A) ( [1, 2 ,13 ] and references therein). This tyro- sine has been...

Ngày tải lên: 18/02/2014, 17:20

... miR16 and miR105 have a 5¢-end of precursor form in the mature form and miR142, miR17, miR302, miR373 and miR9 have both ends in mature forms [7 ,16 ,17 ,24]. Even though the molecular mechanism of miR ... dsl@plaza.snu.ac.kr *These authors contributed equally to this work (Received 18 January 2008, revised 10 March 2008, accepted 17 March 2008) doi :10 .11 11/ j .17 42-4658...

Ngày tải lên: 18/02/2014, 17:20