Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf

... 1297–1309 ª 2010 The Authors Journal compilation ª 2010 FEBS 1309 Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition Yuan ... from the generation of an electro- chemical gradient across the IM forms the basis of the IM w m . During cell death, MP often increases, allow- ing for...

Ngày tải lên: 16/02/2014, 09:20

... in the central cylinder of the root, but not in the lower parts of the hypocotyl (a). Rosette leaves were stained in the vascular tissue of the leaf blade, whereas the petiole and older parts of ... staining within the vascular tissue at the end of the leaf blade, whereas the basal parts close to the petiole remained almost unstained. We observed clear GUS ex...

Ngày tải lên: 18/02/2014, 06:20

... equilibrium. As shown in the inset, the progressive decrease of the molecular ellipticity at k ¼ 200 nm (the absorption region of the peptide bond) reflects the occurrence of a transition between 35° ... 1. The 18 kDa protein present in the elution pattern was identified as the PHI component on the basis of its ability to complement the Fig. 1. SDS/PAGE of PHI a...

Ngày tải lên: 21/02/2014, 00:20

... an overview of the intracellular signaling pathways activated by the EGFR tyrosine kinase, we will describe some of the diverse actions of TKIs on cell growth, cell survival and cell motility. Akt ... cell line A431 cells [56]. These changes are temporally associated with recruitment of tumor cells in the G 1 phase and a marked reduction in the proportion of cells...

Ngày tải lên: 16/02/2014, 09:20

... obesity. Experimental procedures Generation of H-PGDS TG mice The coding region of human H-PGDS was cloned into the downstream sites of the chicken b-actin promoter and the CMV enhancer of the pCAGGS expression vector ... analysis To further assess the effect of H-PGDS overexpression on the increase in adipose tissues, the weights of subcutaneous and visceral adipo...

Ngày tải lên: 16/02/2014, 09:20

... just the result of the larger ionic radius of Cd(II) over Zn(II) and that the difference in amino acid sequence plays a role. One of the most important aspects is the greater dynamics of the Cd(II) 3 -CysS 9 cluster ... in the pro- tein. The modification of the surface-accessible sulfur of cysteine ligands is thought to be the key that unlocks the metals from...

Ngày tải lên: 16/02/2014, 15:20

... enables further glucose import into the cell. Consequently, the PTS enables the cell to maintain a glu- cose concentration gradient through the membrane. The PTS also regulates the uptake of various ... closer to a SIM than the latter. Using these plots and having measured the concentration of EIIAÆP, the investigator can read the values of the remaining eigh...

Ngày tải lên: 18/02/2014, 06:20

... siRNA knock-down of b-catenin The expression of b-catenin was silenced using siRNA tech- nology. The target sequences for the mRNA of b-catenin were 5¢-AAAGCTGATATTGATGGACAG-3¢. The siRNA against ... from granules of leukocytes and are implicated in inflammatory and fibrotic lung diseases. In the present study, the effects of a-defensins on the proliferation and collagen...

Ngày tải lên: 18/02/2014, 06:20

... vessels and their transfer to distant areas in the brain via blood flow; (b) the rapid migration of tumor cells outside blood vessels; and (c) the migration of tumor cells independent of the vascular ... from the Ministry of Education, Culture, Sports, Science and Technology of Japan, a grant from the program ‘Research for the Future’ of the Japan Society for the...

Ngày tải lên: 18/02/2014, 11:20

... together data suggesting that some of the genes involved in the genetics of Lewy body disease, have in common the fact that they impinge on ceramide metabolism. One shortfall of the present theory ... characterized by the disruption of cellular mechanisms leading to the accumulation of iron in the basal ganglia. Mutations in the gene PLA2G6 were recently described as...

Ngày tải lên: 18/02/2014, 14:20