Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle ppt

... of Physiology and Pharmacology, University of Calgary, Alberta, Canada 2 School of Biomedical Sciences, University of Newcastle, Callaghan, NSW, Australia Long-range signaling Biological organs ... 2009) doi:10.1111/j.1742-4658.2009.07437.x Entrained oscillations in Ca 2+ underlie many biological pacemaking phe- nomena. In this article, we review a long-range signaling mechanis...

Ngày tải lên: 16/02/2014, 09:20

... cadherin–catenin complexes The cytoplasmic domain of cadherin interacts with F-actin via b-catenin and a- catenin; b-catenin binds to cadherin and a- catenin, which in turn interacts with F-actin (Fig. ... is activated by an increase in intracellu- lar [Ca 2+ ] [29,30]. If Pyk2 is transiently activated by an increase in intracellular [Ca 2+ ] to phosphorylate b-catenin in two Deve...

Ngày tải lên: 16/02/2014, 09:20

... MINIREVIEW Synchronization of Ca 2+ oscillations: involvement of ATP release in astrocytes Schuichi Koizumi Department of Pharmacology, Faculty of Medicine, University of Yamanashi, Japan Introduction Glia, ... machinery is involved in glutamate release in astrocytes, although nonvesicular mechanisms for glutamate release have also been proposed. In contrast, the mechani...

Ngày tải lên: 16/02/2014, 09:20

... domain; GS, glucan-binding domain-deficient glucosyltransferase-I; GSd, glucansucrase domain; GSGB, glucosyltransferase-I containing a full-length glucan-binding domain; GTF, glucosyltransferase. FEBS ... Methyl a- d-glucopyranoside was used as a glucose analog that is not a substrate of hexokinase in a glucose assay system. The data were analyzed on the basis of the Michaelis–M...

Ngày tải lên: 14/02/2014, 22:20

... monoclonal Z2 antibody in the presence of increasing concentrations of potassium thiocyanate (ranging from 0 to 2.0 m). After incubation and washing, the antibody binding was mea- sured using a goat ... dashed line. (E) Binding of two commercially available IVIg preparations [Endobulin (solid line); Octagam (dashed line)] to human factor H. Data represent mean absorbance values ± st...

Ngày tải lên: 16/02/2014, 15:20

... with endocytosis of intact ETA, in vivo association of the catalytic ETA -A sub- unit and low molecular mass ETA -A fragments was observed in the endosomal apparatus. After an in vitro proteolytic assay with an ... occurring mainly within domain III of ETA -A. Cell-free endosomes preloaded in vivo with ETA intraluminally processed and extraluminally released intact ETA and ETA...

Ngày tải lên: 18/02/2014, 04:20

... dibenzoylhydrazines on larvicidal activity against the Colorado potato beetle Leptinotarsa decemlineata. Pest Manag Sci 57, 858–865. 36 Nakagawa Y, Minakuchi C, Takahashi K & Ueno T (2002) Inhibition of [3H] ... S1. Amino acid alignment of linker region and ligand-binding domain (LBD) of ecdysone receptors. Fig. S2. Amino acid alignment of linker region and ligand-binding domain (...

Ngày tải lên: 18/02/2014, 08:20

... -FNR 1 (AB035644): forward primer, 5¢-ACAACACAAAATGTCAGCTGC AAAA-3¢; reverse primer, 5¢-AAGGCCAAGAAGGAGTC CAAGAAG-3¢; L-FNR 2 (AB035645): forward primer, 5¢-TTGCTTGAGCTGAACAATACAATGAA-3¢; reverse primer, ... from xylem, and vice versa. Glx (glutamine and glutamate: five carbon amide and amino acid) and Asx (asparagine and aspartate: four carbon amide and amino acid) were found to be the main n...

Ngày tải lên: 18/02/2014, 18:20

... consisting of four functional domains arranged in a linear manner. Each one of these domains binds a different substrate or cofactor. In detail, the N-terminal module is the homocysteine (Hcy)-binding ... Protein Assay kit based on the method of Bradford [44]. Standards and sam- ples were assayed in triplicate, according to the manufac- turer’s instructions. Sample absorbances...

Ngày tải lên: 19/02/2014, 05:20

... Bcl-X L expression, and the resistance against ADR-induced apop- tosis, suggesting that EGF transmitted the antiapoptotic signal in such a way that it activated AP1 via a MAP kinase signaling pathway. TMK-1 cells ... signals against ADR-induced apoptosis by causing activation of the phosphatidylinositol-3¢ -OH kinase (PtdIns3-K) ⁄ Akt signaling pathway in human epithelial cell line...

Ngày tải lên: 19/02/2014, 06:20