Tài liệu Regulation of cancer cell metabolism docx

... capacity of antioxidant systems to eliminate ROS and RNS. Regulation of cancer cell metabolism Rob A. Cairns*, Isaac S. Harris* and Tak W. Mak Abstract | Interest in the topic of tumour metabolism ... effect. Only on closer examination of the full metabolic requirements of a cancer cell was the advantage of PKM2 expression revealed. A cancer cell, like any no...

Ngày tải lên: 15/02/2014, 04:20

... of HepG2 cells potentiates proliferation by a PI 3-kinase- meditated activation of the transcription factor activa- tor protein AP-1 [22], corroborating a critical role of cell swelling for cell ... the cell cycle machinery and how cell shrinkage sensitizes cells to apoptotic stimuli requires further scientific effort. Cell hydration may markedly affect the action of drugs. F...

Ngày tải lên: 18/02/2014, 16:20

Ngày tải lên: 13/12/2013, 05:15

Ngày tải lên: 13/12/2013, 05:15

Ngày tải lên: 13/12/2013, 05:15

... problem of fitting a set of N data points (x i ,y i )to a straight-line model y(x)=y(x;a, b)=a+bx (15.2.1) 662 Chapter 15. Modeling of Data Sample page from NUMERICAL RECIPES IN C: THE ART OF SCIENTIFIC ... independent, then each contributes its own bit of uncertainty to the parameters. Consideration of propagation of errors shows that the variance σ 2 f in the value of any fun...

Ngày tải lên: 15/12/2013, 04:15

... fixed limits a and b, one can double the number of intervals in the extended trapezoidal rule without losing the benefit of previous work. The coarsest implementation of the trapezoidal rule is to average ... function at its endpoints a and b.Thefirst stage of refinement is to add to this average the value of the function at the halfway point. The second stage of refinement is to add t...

Ngày tải lên: 15/12/2013, 04:15

... the case of k =2. This is one example of a very general idea that goes by the name of Richardson’s deferred approach to the limit: Perform some numerical algorithm for various values of a parameter ... generalization of the routine qsimp in the last section to integration schemes that are of higher order than Simpson’s rule. The basic idea is to use the results from k successive r...

Ngày tải lên: 15/12/2013, 04:15

... change of variable. float midinf(float (*funk)(float), float aa, float bb, int n) This routine is an exact replacement for midpnt , i.e., returns the n th stage of refinement of the integral of funk from aa to bb , ... endpoints. It is assumed that choose triples the number of steps on each call, and that its error series contains only even powers of the number of steps. The rout...

Ngày tải lên: 15/12/2013, 04:15

Ngày tải lên: 15/12/2013, 04:15