Tài liệu Báo cáo khoa học: Kinetics of dextran-independent a-(1 fi 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I pdf

... compilation ª 2010 FEBS Kinetics of dextran-independent a-(1 fi 3)-glucan synthesis by Streptococcus sobrinus glucosyltransferase I Hideyuki Komatsu 1 , Yoshie Abe 1 , Kazuyuki Eguchi 1 , Hideki ... of nigerooligosaccharides. Efficient glucan synthesis, such that the accumulation of intermediate nigerooligosaccharides (DP = 2)6) is minimized, is explainable by t...

Ngày tải lên: 14/02/2014, 22:20

... intact mitochondria, it is anticipated that there may be a significant production of P i in the vicinity of the ATPase within the matrix. CYPD ablation or its inhibition by cyclosporin A increases ... modulation of PTP open ⁄ closed prob- ability. CYPD is a member of the cyclophilins family encoded by the ppif gene [3], which exhibit peptidyl- prolyl cis ⁄ trans isomerase activit...

Ngày tải lên: 14/02/2014, 19:20

... genes induced by all-trans retinoic acid [4]; KLF4 could induce inhibition of proliferation of VSMC, which is mechanistically linked to a KLF4-induced enhance- ment of the expression of the tumour ... increasing expression of KLF4 in PBMC and THP-1 cells, and identified that induction of KLF4 by HDL 3 promoted the expression of hSR-BI. It has been shown that dis- ruption of...

Ngày tải lên: 18/02/2014, 04:20

... benzimidazoles act as competitive inhibitors of the rat liver methionine synthase, whilst the most active benzothiadiazole (IC 50 ¼ 80 lm) exhibited characteristics of uncompetitive inhibition. ... that the nitrobenzimidazole 1c exhibits the characteristics of mixed inhibition (Fig. 2A) (K i ¼ 26 lm), whilst the nitrobenzothiadiazole 2b is an uncompetitive inhibitor of MetS with res...

Ngày tải lên: 19/02/2014, 05:20

... with copper, they contain an organic prosthetic group reactive with semicarbazide, phenylhydrazine and similar inhibitors of catalytic activity. This prosthetic group was identified [3] as trihydroxyphenylalanine ... phase, simultaneous with the loss of intensity of the UV-vis spectrum of the Cu + -semiquinolamine radical (Fig. 4). All substrates displayed a similar inactivation time,...

Ngày tải lên: 19/02/2014, 12:20

... actin-binding candidate identified in the I- band titin region and we propose, withou t totally exclu- ding other possibilities, that the interaction of T800 with actin is primarily mediated by ... loci where titin is free of interaction with its protein partners and could easily be attacked by V8 protease [58]. Outside the I- band region, it is likely that the interactions of titi...

Ngày tải lên: 19/02/2014, 16:20

... than typing the translations (Brown et al., 1994). Additionally, incorporation of a statistical prediction engine, i. e. a statistical interactive machine translationsystem, to the CAT system is another ... only. In general, N-best rescoring is a simplification of word graph rescoring. As the size of N -best list is increased, the results obtained by N-best list rescoring approach the...

Ngày tải lên: 20/02/2014, 12:20

... (1998) Oxidation of high density lipopro- teins. I. Formation of methionine sulfoxide in apolipoproteins AI and AII is an early event that accompanies lipid peroxidation and can be enhanced by alpha-tocopherol. ... Though it is possible that the inactivation of GAPDH and GR occurs via oxidation of nonactive site residues, that bring about loss of functional integrity, the stoichi...

Ngày tải lên: 21/02/2014, 03:20

... Enhancement of oxidative stress-induced apoptosis by Hsp105a in mouse embryonal F9 cells Nobuyuki Yamagishi, Youhei Saito, Keiichi Ishihara and Takumi Hatayama Department of Biochemistry, Kyoto ... external stresses is accompanied by the activation of a family of stress-activated protein kinases, JNK and p38. Activation of these signalling pathways leads to apoptosis [41,42], an...

Ngày tải lên: 21/02/2014, 03:20

... emphasize the following issues: (i) kinetic character- ization of the new ligand; (ii) its applicability in the binding studies of other corrinoids; and (iii) potential pertinence to the physiological ... cobalamin binding and cubilin recognition sites of intrinsic factor. Biochemistry 44, 3604–3614. 11 Hippe E, Haber E & Olesen H (1971) Nature of vitamin B 12 binding. II. Steric...

Ngày tải lên: 19/02/2014, 05:20