... respiratory disorders in infants and maternalsmoking during pregnancy (69,70) could be partly due to interference of nicotinewith the development of the histaminergic CNS system. Nicotine inhibitshistamine-N-methyltransferase ... disturbances of breathing at both the peripheral and central chemoreceptors, including dopamine, adenosine,endorphins, GABA, and prostaglandins, and these may be upregulated in earlylife (33).When ... noradrenaline-containing cells could exist in theseindividuals, but have yet to be demonstrated.A part from the role of catecholaminergic neurons in chemosensation and arousal, there is increasing...