Tài liệu Báo cáo khoa học: Motion of the Ca2+ -pump captured ppt
... as the ATP-unbound and Ca 2+ -bound E1Ca 2+ form. In the histogram (Fig. 2A) of the dis- tribution of the height of the projection of the embed- ded molecule above the flat membrane surface, the average ... Histograms of the height differences between the top of SERCA and the surface of the membrane. Statistical section analy- ses of SERCA were performed...
Ngày tải lên: 14/02/2014, 14:20
... result of the length restrictions of this minireview. The work of S.W. was supported by the Deutsche Forschungsgemeinschaft (We2843 ⁄ 2-1) and BGAG-Stiftung Walter Hesselbach. The work of S.B. ... that there is a controversy in the literature about the impor- tance of the CagL RGD-motif in T4SS functions and host cell signalling. Another unsolved question is the prop...
Ngày tải lên: 14/02/2014, 19:20
... that the prodomain of ADAM10 acts not only as a transient inhibitor, but also as an internal chaperone in the mat- uration of the enzyme. Accordingly, the viral delivery of furin into the brain of ... point of intervention within the biosynthetic pathway of ADAM10 is provided by directly interfer- ing with the expression of the gene for ADAM10: the promoter reg...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf
... preferentially the phosphorylation of the p46 isoform of JNK, whereas sorbitol treatment induced phosphorylation of both the p46 and p55 isoforms. To confirm functional activation of the JNK signaling ... phosphorylation of the transcription factor c-JUN was attenuated. Upon expression of wild-type JSP1, a subpopula- tion of cells, with the highest levels of the p...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Regulation of the members of the mammalian heat shock factor family doc
... development of the lens and maintenance of the olfactory epithelium [102]. The first evidence for a developmental function of HSF4 was provided by population genetic studies where mutations of the Hsf4 ... how the developmental activity of HSF1 is regulated. The identity of the developmental signal that promotes a monomer-to-trimer transition of HSF1 in the olfact...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: Structure of the putative 32 kDa myrosinase-binding protein from Arabidopsis (At3g16450.1) determined by SAIL-NMR docx
... 5875 Comparison of NMR spectra of SAIL and UL At3g16450.1 Although the concentration of the SAIL protein was lower than that of the UL protein by a factor of three (SAIL, 0.2 mm; UL, 0.6 mm), the NMR ... of SAIL Fig. 3. Secondary structure of At3g16450.1. (A) Ribbon representa- tion of the NMR structure of At3g16450.1. These figures were pre- pared using MOLMOL [25]...
Ngày tải lên: 18/02/2014, 14:20
Tài liệu Báo cáo khoa học: Switching of the homooligomeric ATP-binding cassette transport complex MDL1 from post-translational mitochondrial import to endoplasmic reticulum insertion pptx
... inter- acts with the TOM receptor, responsible for the trans- location of the preproteins to the translocase of the inner mitochondrial membrane (TIM)23 complex located in the IMM. The presequence ... hydrolysis in the nucleotide-binding domain of the ABC transporter HlyB. EMBO J 24 , 1901–1910. 38 Kuhnke G, Neumann K, Mu ¨ hlenhoff U & Lill R (2006) Stimulation o...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Analysis of the molecular dynamics of medaka nuage proteins by fluorescence correlation spectroscopy and fluorescence recovery after photobleaching doc
... eggs in the one-cell stage to visualize the localization and to mea- sure the mobility of the components in the PGCs. The medaka embryo was peeled off the chorion, and the segment containing the ... movement in the granules and diffused in the cytosol of HeLa cells, just as in the medaka embryo. The other two gene products, Nanos and Tudor of the medaka, whic...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx
... in the protein stability of our mutants. There- fore, these conclusions strengthen our hypothesis that the catalytic efficiencies of the recombinant enzymes used in our study were related to the ... phe- nol as the tyrosine R group. This system has been used previously to analyze the geometry of the tyrosine stacked on the si-face of the flavin in FNRs [12]. The sing...
Ngày tải lên: 18/02/2014, 17:20
Tài liệu Báo cáo khoa học: Bioimaging of the unbalanced expression of microRNA9 and microRNA9* during the neuronal differentiation of P19 cells doc
... means located 44 bp upstream of the first base pair at the 5¢-end of pre-miR-9-1 defined as +1. FLuc is the ORF of the Firefly Luciferase reporter gene. (C) In vitro bioluminescent assay of pri-miR9-1 during ... imaging of gene expression of endoge- nous pri-miR9 during neurogenesis. To image in vivo the endogenous expression of the pri-miR9 in small animals, 2.5 · 10 6...
Ngày tải lên: 18/02/2014, 17:20