... centrally located in the apolar faceof the AP1 a- helix, and previous studies have shownthat similarly located glutamate residues are important for the antimicrobial action of other a- AMPs alsopredicted ... membranes, the interactionparameter, a, and the mixing enthalpy, DH, were com-puted (Table 3). It can be seen from Table 3 that, in the absence of AP1, values for a and DH are negative for these ... 389–395.43 Sospedra P, Espina M, Gomara MJ, Alsina MA, HaroI & Mestres C (2001) Study at the air ⁄ water interface of a hepatitis A N-acetylated and C-amidated syntheticpeptide (AcVP3 (110–121)-NH2)....