... The expression of T-bet has beenseen within a wide variety of tissues and cells in theGinbuna crucian carp [27] and, in mammals, in thelung tissue of mouse and spleen and thymus of humanand ... kidney,gill, gut, liver and skin tissue of healthy fish (data notshown). After stimulation of kidney cells with a variety of immunostimulants, the expression of t-bet, stat6and foxp3, together with ... first time in fish. The availability of sequenced fish genomes has allowed the discovery of a number of immune relevant genes using the synte-ny (conservation of gene order) found between thehuman...