Lý thuy院t xác th詠c chéo (cross validation)

Một phần của tài liệu Nghiên cứu đánh giá chất lượng giấc ngủ bằng tín hiệu điện não và biến thiên nhịp tim (Trang 67)

Xác th詠c chéo là k悦 thu壱v"8ƒpj"ikƒ"eƒe"o»"j·pj"vtqpi"j丑c máy b茨ng cách hu医n luy羽n nhi隠u mô hình c栄a t壱p h嬰p con c栄a d英 li羽w"8亥w"x q"x "8ƒpj"ikƒ"ej¿pi"vt‒p"o瓜t t壱p h嬰p con khác. Xác th詠c chéo K-fold, d英 li羽w"8亥u v q"8逢嬰c chia ra thành K t壱p h嬰p con, k悦 thu壱t s胤 s穎 d映ng (K-1) t壱r"eqp"8吋 ti院n hành hu医n luy羽n (training) và 1 t壱p con còn l衣k"8吋8ƒpj"ikƒ"o»"j·pj *vguvkpi+0"Swƒ"vt·pj"p {"8逢嬰c l員p K l亥n v噂i các t壱p h嬰r"eqp"8逢嬰c thay phiên nhaụ

Hình 3.15 là m瓜t ví d映 c栄a xác th詠c chéo K-fold (K = 10). D英 li羽w"dcp"8亥u

8逢嬰c chia làm 10 t壱r"eqp."vtqpi"8„"; t壱r"eqp"8吋 hu医n luy羽n (ô xanh-training set) và 1 t壱r"eqp"8吋8ƒpj"ikƒ"*»"x pi"Î validation set). T鰻ng c瓜ng có 10 vt逢運ng h嬰p t衣o thành 10 mô hình khác nhau 泳ng v噂i vi羽c thay phiên các t壱r"eqp."8違m b違o cho t医t c違 các d英

li羽w"8隠w"8逢嬰c hu医n luy羽p"x "8ƒpj"ikƒ0永ng v噂i m厩i mô hình s胤e„"8瓜 chính xác riêng,

ucw"8„"8瓜 chính xác t鰻pi"8逢嬰e"v pj"f逢噂i d衣ng giá tr鵜 trung bình c瓜ng tr瑛 8瓜 l羽ch chu育n.

3.3.8.2 Rj逢挨pi"rjƒr"phân lo衣i nhi隠u l噂p d詠a trên chi院p"n逢嬰c Ðqpg-vs-qpgÑ.

Rj逢挨pi"rjƒr"Ðqpg-vs-qpgÑ"vk院p c壱p"dcp"8亥u gi嘘pi"pj逢"xk羽c phân lo衣i t瑛ng 2 l噂p

8»k"o瓜v"pj逢vt‒p."vw{"pjk‒p"8亥u ra là m瓜t k院t qu違 duy nh医t (cho c違 3 l噂p W, N1+N2+R và N3). T鰻ng quát, khi có 倦 l噂p d英 li羽u khác nhau, s胤 xây d詠pi"8逢嬰c 賃岫賃貸怠岻

態 b瓜 phân lo衣i hai l噂p [41]0"A嘘i v噂i bài toán 3 l噂p trong rj逢挨pi"rjƒr"p {"vj·"ÐhgcvwtgavtckpÑ" 8逢嬰c chia làm 賃岫賃貸怠岻

態 噺戴抜岫戴貸怠岻態 噺 ぬ t壱p h嬰p nh臼 ch泳c"eƒe"xgevqt"8員e"vt逢pi"e栄c"8»k"

m瓜t trong 3 ikck"8q衣n gi医c ng栄 pj«p"v逢挨pi"泳pị"ucw"8„"8逢嬰e"8go"x q"d瓜 phân lo衣i SVM 8吋 vjw"8逢嬰e"dc"o»"j·pj"C."D."E"8吋 c違 ba mô hình này s胤 d詠 8qƒp"pj«p"e栄a

ÐhgcvwtgavguvÑ cùng lúc. M ej"vj逢噂c c栄a b瓜 phân lo衣i t衣o b荏k"rj逢挨pi"rjƒr"Ðqpg-vs-

qpgÑ l噂p"j挨p"uq"x噂k"rj逢挨pi"rjƒr"Ðqpg-vs-allÑ. Tuy nhiên."m ej"vj逢噂c c栄a quy ho衣ch

vq p"rj逢挨pi"*quadratic programming) trong m厩i b瓜 phân lo衣i nh臼j挨p."fq"8„"e„"vj吋

hu医n luy羽n nhanh. J挨p"p英c."rj逢挨pi"rjƒr"Ðqpg-vs-oneÑ8嘘i x泳pi"j挨p"uq"x噂k"rj逢挨pi" rjƒr"Ðqpg-vs-allÑ.

3.3.8.3 Rj逢挨pi"rjƒr"phân lo衣i nhi隠u l噂p d詠a trên chi院p"n逢嬰c Ðqpg-vs-cnnÑ.

Rj逢挨pi"rjƒr"Ðqpg-vs-cnnÑ"e„"e医u trúc g亥n gi嘘ng v噂k"rj逢挨pi"rjƒr"Ðqpg-vs-qpgÑ"

và ch雨 có 8k吋m khác 荏 ch厩 dán nhãn d英 li羽w"mjk"8go"x q"d瓜 phân lo衣ị T鰻ng quát, khi có 倦 l噂p d英 li羽u khác nhau, s胤 xây d詠ng 倦 b瓜 phân lo衣i hai l噂p, m厩i b瓜 dành cho m瓜t l噂p c映 th吋*8逢嬰c dán nhãn ÐrqukvkxgÑ+."x "fƒp"pj«p"ÐpgicvkxgÑ"ejq"v医t c違 các l噂p còn l衣ị Pj逢嬰e"8k吋m c栄c"rj逢挨pi"rjƒr"p {"n "v壱r"vtckpkpi"mj»pi"e¤p"8嘘ị Gi違 s穎 các l噂p

e„"épi"m ej"vj逢噂c c栄a t壱p training, t益 l羽ÐrqukvkxgÑ"x "ÐpgicvkxgÑ"vtqpi"o厩i b瓜 phân lo衣i là 怠

賃貸怠. Vtqpi"vt逢運ng h嬰r"p {."v pj"8嘘i x泳ng c栄c"d k"vqƒp"dcp"8亥u b鵜 m医t [41].

3.3.8.4 Rj逢挨pi"rjƒr8ƒpj"ikƒ"o»"j·pj theo t瑛pi"8嘘k"v逢嬰ng thí nghi羽m (subject dependent).

Khi phân chia t壱p training và t壱p testing m瓜t cách ng磯u nhiên trong quá trình xác th詠c chéo, c違 hai t壱p d英 li羽w"p {"8隠u có m磯w"v逢挨pi"泳ng v噂i m瓜v"8嘘k"v逢嬰ng ho員c c栄a nhi隠w"8嘘k"v逢嬰pi0"Fq"8„."mjk"d瓜 phân lo衣i c嘘 g逸ng d詠8qƒp"eƒe"n噂p d英 li羽u không nhìn th医y thì nó có th吋 nh壱n ra các m磯w"v逢挨pi"v詠 trong t壱p training. Vì v壱y, cách phân lo衣i

p {"8逢嬰c g丑i là phân lo衣i ph映 thu瓜c ch栄 th吋 (subject dependent). Pj逢嬰e"8k吋m c栄a

rj逢挨pi"rjƒr"p {"n "n医y d英 li羽u t瑛 m厩k"eƒ"pj¤p"vj逢運pi"mj»pi"8栄 8吋 thi院t k院 m瓜t mô hình t嘘t, vì sinh lý c栄a m厩k"eqp"pi逢運i r医v"mjƒe"pjcw0"Vw{"pjk‒p."8¤{"n衣i ph違n ánh t嘘t s詠 khác bi羽t sinh lý gi英a các ch栄 th吋 khác nhau [42].

Tóm l衣k."rj逢挨pi"rjƒr"p {"8逢嬰c th詠c hi羽p"pj逢"vtqpi"x”pi"n員p theo th泳 t詠 t瑛pi"8嘘i

v逢嬰ng c栄a b瓜 d英 li羽u 1:

- T壱p training: d英 li羽u t瑛8嘘k"v逢嬰ng th泳 n - T壱p testing: d英 li羽u t瑛8嘘k"v逢嬰ng th泳 n

3.3.8.5 Rj逢挨pi"rjƒr"8ƒpj"ikƒ"o»"j·pj8瓜c l壱p v噂k"8嘘k"v逢嬰ng thí nghi羽m (subject independent).

Pi逢嬰c l衣k."rj逢挨pi"rjƒp phân lo衣k"8瓜c l壱p ch栄 th吋 *uwdlgev"kpfgrgpfgpv+"8逢嬰c th詠c hi羽n b茨ng cách s穎 d映ng t壱p training c栄a (n-3+"8嘘k"v逢嬰ng và t壱p testing t瑛 d英 li羽u c栄c"8嘘k"v逢嬰ng còn l衣ị

Trong th詠c t院, m映c tiêu c栄c"eƒe"rj逢挨pi"rjƒr"rj¤p"nq衣i là thi院t k院 m瓜t mô hình chung t瑛 d英 li羽u t鰻ng h嬰p t瑛 nhi隠w"eƒ"pj¤p."ucw"8„"8逢嬰c cá nhân hóa cho t瑛ng cá nhân c映 th吋. V噂i m映e"8 ej"8„."d瓜 phân lo衣i có th吋 h丑c không ch雨 t瑛 d英 li羽u c栄a (n Î

1) 8嘘k"v逢嬰ng, mà còn t瑛 m瓜t ph亥n nh臼 d英 li羽u t瑛8嘘k"v逢嬰ng th泳p"x "8逢嬰c ki吋m tra trong ph亥n còn l衣ị Vt逢運ng h嬰p này l衣i có ph亥n gi嘘pi" rj逢挨pi" rjƒr" Ðuwdlgev" fgrgpfgpvÑ"d荏i eƒe"8員e"vt逢pi"mj»pi"8逢嬰c bi院v"vt逢噂c hoàn toàn v噂i b瓜 phân lo衣i [42].

Tóm l衣k."rj逢挨pi"rjƒr"p {"8逢嬰c th詠c hi羽p"pj逢"vtqpi"x”pi"n員p theo th泳 t詠 t瑛pi"8嘘i

v逢嬰ng c栄a b瓜 d英 li羽u 1:

- T壱p training: d英 li羽u t瑛 (n-3+"8嘘k"v逢嬰ng và 0% c栄a d英 li羽u t瑛8嘘k"v逢嬰ng th泳 n. - T壱p testing: 100% d英 li羽u t瑛8嘘k"v逢嬰ng th泳 n.

3.3.9 Eƒe"vj»pi"u嘘"8ƒpj"ikƒ"m院v"sw違rj¤p"nq衣k"e栄c"o»"j·pj"j丑e"oƒ{0

Ü Oc"vt壱p"pj亥o"n磯p"*Eqphwukqp"Ocvtkz+: là ma tr壱p"8逢嬰e"u穎"f映pi8吋"8ƒpj"ikƒ" m院v"sw違"e栄c"eƒe"d k"vqƒp"rj¤p"nq衣k [43]0"O瓜v"oc"vt壱p"pj亥o"n磯p"e„"f衣pi"pj逢"ucw<

X噂k<

Vtwg"rqukvkxg"*VR+<"U嘘"n逢嬰pi"o磯w"vjw瓜e"n噂r"Z"8逢嬰e"rj¤p"nq衣k"ej pj"zƒe"x q"n噂r"Z Hcnug"rqukvkxg"*HR+<"U嘘"n逢嬰pi"o磯w"mj»pi"vjw瓜e"n噂r"Z"d鵜"rj¤p"nq衣k"pj亥o"x q"n噂r"Z Vtwg"pgicvkxg"*VP+<"U嘘"n逢嬰pi"o磯w"mj»pi"vjw瓜e"n噂r"Z"8逢嬰e"rj¤p"nq衣k"ej pj"zƒe Hcnug"pgicvkxg"*HP+<"U嘘"n逢嬰pi"o磯w"vjw瓜e"n噂r"Z"d鵜"rj¤p"nq衣k"pj亥o

Ü A瓜"ej pj"zƒe"*Ceewtce{+<"V益"n羽"ej pj"zƒe"x "v益"n羽"o逸e"uck"n亥o"8逢嬰e"u穎"f映pi" pjk隠w"pj医v"vtqpi"eƒe"vjw壱v"vqƒp"rj¤p"nq衣k0"V益"n羽"ej pj"zƒe"*8瓜"ej pj"zƒe+"n "v益"n羽"ik英c" eƒe"o磯w"8逢嬰e"rj¤p"nq衣k"8¿pi"uq"x噂k"v鰻pi"u嘘"n逢嬰pi"o磯w [44]0"V益"n羽"o逸e"uck"n亥o"n "v益" n羽"ik英c"eƒe"o磯w"mj»pi"8逢嬰e"rj¤p"nq衣k"8¿pi"*okuencuukhkgf"ucorngư"uq"x噂k"v鰻pi"u嘘" n逢嬰pi"o磯w0A瓜"ej pj"zƒe"8逢嬰e"v pj"vjgq"e»pi"vj泳e (3.30):

Ceewtce{"?"VR"-"HP"-"VP"-"HRVR"-"VP (3.30)

Ü A瓜"pj衣{"*Ugpukvkxkv{"jc{"Tgecnn+<"V益"n羽"rj¤p"nq衣k"ej pj"zƒe"eƒe"o磯w"vjw瓜e" n噂r"Z"vt‒p"v鰻pi u嘘"eƒe"o磯w"8逢嬰e"rj¤p"nq衣k"vt‒p"n噂r"Z [44]0"A瓜 pj衣{"e pi n "v益"u嘘"

True Positive Rate (TPR) e栄c"o»"j·pj"rj¤p"nq衣k0"A瓜"pj衣{"8逢嬰e"v pj"vjgq"e»pi"vj泳e

(3.31):

Ugpukvkxkv{"*VRT+"?"VR"-"HPVR (3.31)

Ü A瓜"8員e"jk羽w"*Urgekhkekv{+<"V益"n羽"rj¤p"nq衣k"ej pj"zƒe"eƒe"o磯w"mj»pi"vjw瓜e"n噂r" Z"vt‒p"v鰻pi"u嘘"eƒe"o磯w"8逢嬰e"rj¤p"nq衣k"mj»pi"vjw瓜e"n噂r"Z0"A瓜"8員e jk羽w"e pi"ej pj" n "v益"u嘘"Vtwg"Pegative Rate (TNR) e栄c"o»"j·pj"rj¤p"nq衣k [44]0"A瓜"8員ejk羽w"8逢嬰e"v pj" vjgq"e»pi"vj泳e (3.32):

Urgekhkekv{"*VPT+"?"VP"-"HRVP (3.32)

Ü A瓜"ejw育p"zƒe"*Rtgekukqp+<jc{"8逢嬰e"i丑k"n "ikƒ"vt鵜"f詠"8qƒp"Rqukvkxg"*Rqukvkxg"

Prediction Value - RRX+."n "v益"u嘘"f詠"8qƒp"8¿pi"e栄c"Rqukvkxg"vt‒p"v医v"e違"eƒe"m院v"sw違"f詠" 8qƒp"n "Rqukvkxg."d医v"m吋"n "8¿pi"jc{"uck0"

2ø̋˚ÆœÆæº"岫228岻 噺 "62 髪 (262 (3.33)

Ü Ikƒ"vt鵜"f詠"8qƒp"Pgicvkxg"*Pgicvkxg"Rtgfkekqp"Xcnwg"Î NPV): pi逢嬰e"n衣k"x噂k" RRX."8¤{"n "v益"u嘘"f詠"8qƒp"8¿pi"e栄c"Pgicvkxg"vt‒p"v医v"e違"eƒe"f詠"8qƒp"n "Pgicvkxg."d医v" m吋"8¿pi"jc{"uck0

028 噺 60 髪 (060 (3.34)

Ü V益"n羽"rjƒv"jk羽p"pj亥o"Rqukvkxg"(FPR - False Positive Rate): v雨"n羽"rjƒv"jk羽p" pj亥o"e栄c"m院v"sw違"f詠"8qƒp"Rqukvkxg0V益"n羽"p {"ejq"dk院v"e„"dcq"pjk‒w"rj亥p"vt<o"pj壱p"

sai Negative thành Positive

HRT"?"3"/"Ugpvkxkv{"?" HR

VP"-"HR (3.35)

Ü V益"n羽"rjƒv"jk羽p"pj亥o"Pgicvkxg"*HPR - False Negative Rate): v雨"n羽"rjƒv"jk羽p" pj亥o"e栄c"m院v"sw違"f詠"8qƒp"Negativẹ V益"n羽"p {"ejq"dk院v"e„"dcq"pjk‒w"rj亥p"vt<o"pj壱p"

sai Negative thành Positive

(04 噺 な 伐 5ı̋˚Æ̨Æ˚Æß (3.36)

Ü F1-score: là giá tr鵜 t鰻ng h嬰p tính t瑛8瓜ej pj"zƒe"x "8瓜 chu育n xác. Nó th吋 hi羽n s詠 hài hoà gi英a hai giá tr鵜 nàỵ Giá tr鵜 n "v逢荏ng c栄a F1 score là b茨ng 1 khi Accuracy và Precision 8隠u cao và ti羽m c壱n v隠 1. Công th泳c tính F1 score cho bài toán phân lo衣i hai l噂p:

(な 伐 œ˚æø̋ 噺 #˚˚­ø̇˚ 抜 2ø̋˚ÆœÆæº

#˚˚­ø̇˚ 髪 2ø̋˚ÆœÆæº (3.37)

A嘘i v噂i bài toán phân lo衣i t瑛 2 l噂p tr荏 lên (nhi隠u l噂p), giá tr鵜 F1-score còn có thêm các thông s嘘8ƒpj"ikƒ"mjƒe"pj逢"ucw<

- Micro-avaraged F1-ueqtg<"8逢嬰c tính trên t鰻ng TP, t鰻ng FP và t鰻ng FN c栄a mô hình phân lo衣ị Thông s嘘 này không xem xét t瑛ng l噂p riêng l飲, mà tính toán trên s嘘 li羽u chung.

- Weight-averaged F1-score: Khác v噂i Macro F1, thông s嘘 này tính toán các giá tr鵜 kèm theo tr丑ng s嘘. Tr丑ng s嘘荏8¤{"n "v鰻ng s嘘 m磯u c栄a m厩i l噂p d英 li羽ụ Giá tr鵜 p {"8吋8ƒpj"ikƒ"ejq"d k"vqƒp"rj¤p"nq衣k"pj逢pi"u嘘 m磯u các l噂r"mj»pi"8隠u nhaụ

Ü A逢運pi" eqpi" TQE" *Tgegkxgt" qrgtcvkpi" ejctcevgtkuvke" ewtxg+: cho phép

mj違q"uƒv"v医v"e違"eƒe"mj違"p<pi"x隠"eƒe"pi逢叡pi"rj¤p"nq衣k"8吋"v·o"tc"pi逢叡pi"rj¤p"nq衣k"v嘘v" pj医v0"TQE"e„"vt映e"jq pj"n "HRT"x "vt映e"vwpi"n "VRT0"A逢運pi"eqpi"e pi"i亥p"x隠"rj c" i„e"vtƒk"vt‒p"*rj c"v¤{"d逸e+"vj·"8瓜"ej pj"zƒe"mjk"rj¤p"nq衣k"u胤"e pi"ecq [33]0"Pj英pi" 8k吋o"e pi"i亥p"8k吋o"*2=3+"vj·"8k吋o"8„"u胤"e„"pi逢叡pi"rj¤p"nq衣k"v嘘v"pj医v [45].

AUC (Area under curve)<"fk羽p"v ej"f逢噂k"TQE"ejq"rjfir"uq"uƒpj"8逢運pi"ROC này

x噂k"eƒe"8逢運pi"TQE"mjƒe0"TQE"n "o瓜v"8逢運pi"eqpi"vj吋"jk羽p"zƒe"uw医v"vj·"CWE"8衣k" fk羽p"ejq"o泳e"8瓜"jq員e"vj逢噂e"8q"mj違"p<pi"rj¤p"nq衣k. A逢運pi"TQE"e„"CWE"e pi"n噂p" *e pi"vk院p"x隠"3+"vj·"8瓜"pj衣{"e pi"n噂p0CWE"vj逢運pi"e„"ikƒ"vt鵜"v瑛"207"8院p"3 [45].

- AUC = 0.5: o»"j·pj"mj»pi"e„"mj違"p<pi"rj¤p"nq衣k"ik英c"n噂r"rqukvkxg"x "n噂r" pgicvkxg."8¤{"n "vt逢運pi"j嬰r"rj¤p"nq衣k"v羽"pj医v0

- AUC 半"0.97<"mj違"p<pi"rj¤p"nq衣k"e栄c"o»"j·pj"e„"vj吋"ej医r"pj壱p"8逢嬰e. - AUC = 1: o»"j·pj"e„"mj違"p<pi"rj¤p"nq衣k"ej pj"zƒe.

77 Hình 3.17: A⇔ぜpi"eqpi"TQC [46] J·pj"603<"V p"jkうw"8kうp"p«q"*jck"m‒pj"E5"x "E6+" eてc"oじv"fの"nkうw"3 A⇔ぜpi"eqpi"TQE J·pj"603<"V p"jkうw"8kうp"p«q"*jck"m‒pj"E5"x "E6+" eてc"oじv"fの"nkうw"3" J·pj"604<"V p"jkうw"8kうp"p«q"*dc"m‒pj"H5."E5"x " Q3+"eてc"dじ"fの"nkうw 4"vt⇔ずe"x "ucw"mjk"8⇔ぢe"nがe"pjkいw

J·pj"603<"V p"jkうw"8kうp"p«q"*jck"m‒pj"E5"x "E6+"eてc" oじv"fの"nkうw"3 A⇔ぜpi"eqpi"TQE

V鰻pi"m院v"n衣k."p院w"vc"swcp"vt丑pi"xk羽e"pj壱p"f衣pi"n噂r"Rqukvkxg"vj·"o»"j·pj"rj¤p" nq衣k"ejq"eƒe"ikƒ"vt鵜"Ceewtce{."Recall."VRT"ecq"x "HRT"vj医r"u胤 8逢嬰e"8ƒpj"ikƒ"ecọ

Pi逢嬰e" n衣k." p院w" vc" swcp" v¤o" xk羽e" pj壱p" f衣pi" Pgicvkxg" vj·" eƒe" ikƒ" vt鵜" Ceewtce{." Urgekhkekv{."PRX"ecq"x "HPR"vj医r"u胤 l "o映e"vk‒w"j逢噂pi"8院p"e栄c"o»"j·pj"rj¤p"nq衣k0 X·" x壱{." nw壱p" x<p" j逢噂pi" 8院p" 8ƒpj" ikƒ" eƒe" ikƒ" vt鵜" Ceewtce{." Tgecnn." Rtgekukqp" x "

Weighted Macro F1-scorẹ

3.3.10 V pj"vqƒp"vj»pi"u嘘"ej医v"n逢嬰pi"ik医e"pi栄.

Ucw"mjk"eƒe"ikck"8q衣n gi医c ng栄8«"8逢嬰c phân lo衣i, các thông s嘘 ch医v"n逢嬰ng gi医c ng栄<"8瓜 tr宇 gi医c ng栄 (SL), hi羽u qu違 gi医c ng栄 (SE, công th泳c 2.1), t益 l羽 ph亥p"vt<o"e栄a ng栄 sâu (N3 %, công th泳c 2.4) s胤8逢嬰c tính toán d詠a trên nhãn d詠8qƒp"v瑛 mô hình phân lo衣ị

EJ姶愛PI"6<"M蔭V"SW謂"XÉ"DÉP"NW一P

4.1 M院v"sw違"vk隠p"z穎"n#"v p"jk羽w. 4.1.1 V p"jk羽w"8k羽p"p«q.

Ü D瓜"f英"nk羽w"3.

D瓜"f英"nk羽w"3"e„"v亥p"u嘘"n医{"o磯w"n "34:"J¦0"V p"jk羽w"GGI"x "GEI"8隠w"8«"8逢嬰e"n丑e" pjk宇w"8k羽p"n逢噂k"72J¦"x "n丑e"pi逢叡pi"vj»pi"vj医r-thông cao v瑛"205"Î 57"J¦"*8嘘k"x噂k"

EEG) và 0.3 Î 75 Hz (ECG). Quá trình n丑e"vj»pi"ecq"*>205"J¦+"t医v"swcp"vt丑pi"pj茨o" rj¤p"dk羽v"8逢嬰e"ej pj"zƒe"eƒe"u„pi"ej壱o"Unqy"ycxgu"*>"6"J¦+"e„"zw医v"jk羽p"jc{"mj»pị" u„pi"ej壱o"n "8員e"vt逢pi c栄c"ikck"8q衣p"pi栄"u¤w"*P5+"pj逢"8«"p‒w"荏"rj亥p"vt‒p0

Ü D瓜"f英"nk羽w"4.

Tín hi羽u EEG và ECG t瑛 b瓜 d英 li羽u th詠c nghi羽m (d英 li羽u 2) là d英 li羽u thô vì th院 tín hi羽u này b鵜 nhi宇w"8k羽p"n逢噂i và nhi宇u do chuy吋p"8瓜ng m逸v"jc{"e挨0"X·"vj院 vi羽c kh穎 nhi宇u và kh穎 trôi tín hi羽u GGI"8逢嬰e"zgo"n "d逢噂c ti隠n x穎n#"8吋e„"8逢嬰c k院t qu違

chính xác cho các phân tích 荏 ph亥n x穎 lý chính. C映 th吋, tín hi羽u s胤8逢嬰e"8逢c"swc"d瓜

l丑c Notch 50 Hz l丑c nhi宇w"8k羽p"n逢噂i và l丑e"pi逢叡ng l丑e"pi逢叡ng thông th医p-thông cao

t瑛 0.3 Î57"J¦"*8嘘i v噂i EEG) và 0.3 Î 75 Hz (ECG). Hình 4.2 th吋 hi羽n d英 li羽w"vt逢噂c và sau khi l丑c nhi宇u c栄c"ec"8q"RUI230

4.1.2 V p"jk羽w"8k羽p"vko"ÎDk院p"vjk‒p"pj鵜r"vko.

V p"jk羽w"GEI"ucw"mjk"8逢嬰e"n丑e"pjk宇w"u胤" 8逢嬰e"pj壱p"fk羽p rj泳e"j嬰r"STU v瑛" vjw壱v"vqƒp Pan Tompkins [47] trong Matlab. Hình 4.3 ejq"vj医{"m院v"sw違"zƒe"8鵜pj"8雨pj" T"t医v"v嘘v"vt‒p"vt映e"vj運k"ikcpe栄c"vjw壱v"vqƒp8逢嬰e"xk院v"d荏k"Sedghamiz [48]. Vt映e"jq pj" e栄c"8欝"vj鵜"n "vj泳"v詠"e栄c"eƒe"mjq違pi"TT"x "vt映e"vwpi"n "vj運k"ikcp"e栄c"mjq違pi"TT"8„"

thgq"8挨p"x鵜"ik¤{0 T瑛 m院v"sw違"zƒe"8鵜pj"8雨pj"p {"n "e挨"u荏"8吋"v pj"vqƒp"tc"eƒe"mjq違pi"

RR và v胤 p‒p"8逢嬰e"v p"jk羽w"JTX0"V p"jk羽w"JTX"ej pj"n "v p"jk羽w"8吋"mj違q"uƒv"jq衣v" 8瓜pi"ej泳e"p<pi"e栄c"vko"vtqpi"eƒe"ikck"8q衣p ik医e"pi栄 8逢嬰e"u穎"f映pi"ejq"pijk‒p"e泳w"

nàỵ

Hình 0.87J·pj"604<"V p"jkうw"8kうp"p«q"*dc"m‒pj"H5."E5"x "Q3+"eてc"dじ"fの"nkうw"4"vt⇔ずe"x "ucw"mjk" 8⇔ぢe"nがe"pjkいw

4.2 M院v"sw違"vt ej"zw医v"8員e"vt逢pi. 60403"M院v"sw違"ej丑p"j羽"u嘘"Ycxgngv"rj́"j嬰r"x噂k"jck"d瓜"f英"nk羽w. Ü D瓜"f英"nk羽w"3. 0.89J·pj"606<"U¬"8げ"e¤{"Ycxgngv"x "eƒe"jう"uぐ"Ycxgngv"8⇔ぢe"ejがp"とpi"xずk"vなpi"fVk"sóng eてc"dじ"fの"nkうw"3"*vZp"uぐ"nX{"odw"hu"?"34:"J¦+. Hình 0.88J·pj"605<"Mxv"swV"dhv"8えpj"T"eてc"v p"jkうw"GEI"vな"dじ"fの"nkうw"3.

Ü D瓜"f英"nk羽w"4.

60404"M院v"sw違"v pj"v益"n羽"e»pi"uw医v"vt‒p"eƒe"f違k"u„pi.

D違pi"603<Ikƒ"vt鵜"v益"n羽"e»pi"uw医v"8"f違k"u„pi"v逢挨pi"泳pi"x噂k"ikck"8q衣p"ik医e"pi栄"e栄c ca

8q ucđb026 Îd瓜"f英"nk羽w"30.11

Epoch V益"n羽"e»pi"uw医v"T Ikck"8q衣p

Epoch Beta 1 Beta 2 Spindle Alpha Theta Delta

30 0.525 0.135 0.126 0.062 0.071 0.081 W 31 0.155 0.104 0.140 0.080 0.199 0.323 W 32 0.350 0.099 0.125 0.072 0.196 0.157 W 33 0.082 0.077 0.127 0.265 0.290 0.160 W 34 0.084 0.080 0.120 0.319 0.268 0.128 W 35 0.069 0.050 0.117 0.167 0.390 0.208 N1 36 0.068 0.041 0.096 0.114 0.463 0.217 N1 È È È È È È È È 52 0.027 0.022 0.087 0.066 0.506 0.293 N1 53 0.026 0.021 0.068 0.059 0.522 0.305 N1 54 0.022 0.021 0.072 0.085 0.525 0.276 N2 55 0.019 0.016 0.064 0.071 0.566 0.264 N2 56 0.012 0.012 0.055 0.060 0.511 0.350 N2 È È È È È È È È 0.93 J·pj"607<"U¬"8げ"e¤{"Ycxgngv"x "eƒe"jう"uぐ"Ycxgngv"8⇔ぢe"ejがp"とpi"xずk"vなpi"fVk"u„pi" eてc"dじ"fの"nkうw"4"*vZp"uぐ"nX{"odw"hu"?"722"J¦+ J·pj"607<"U¬"8げ"e¤{"Ycxgngv"x "eƒe"jう"uぐ"Ycxgngv"8⇔ぢe"ejがp"とpi"xずk"vなpi"fVk"u„pi" eてc"dじ"fの"nkうw"4"*vZp"uぐ"nX{"odw"hu"?"722"J¦+ J·pj"607<"U¬"8げ"e¤{"Ycxgngv"x "eƒe"jう"uぐ"Ycxgngv"8⇔ぢe"ejがp"とpi"xずk"vなpi"fVk"u„pi" eてc"dじ"fの"nkうw"4"*vZp"uぐ"nX{"odw"hu"?"722"J¦+ J·pj"607<"U¬"8げ"e¤{"Ycxgngv"x "eƒe"jう"uぐ"Ycxgngv"8⇔ぢe"ejがp"とpi"xずk"vなpi"fVk"u„pi" eてc"dじ"fの"nkうw"4"*vZp uぐ"nX{"odw"hu"?"722"J¦+

71 0.010 0.011 0.047 0.043 0.452 0.438 N2 72 0.017 0.014 0.049 0.047 0.391 0.482 N2 73 0.014 0.016 0.046 0.060 0.465 0.399 N3 74 0.012 0.012 0.039 0.054 0.399 0.484 N3 75 0.011 0.013 0.046 0.048 0.462 0.420 N3 È È È È È È È È 173 0.019 0.017 0.061 0.046 0.446 0.410 N2 174 0.022 0.017 0.055 0.074 0.449 0.384 N2 175 0.023 0.024 0.095 0.057 0.440 0.362 REM 176 0.055 0.038 0.094 0.084 0.469 0.260 REM 177 0.050 0.035 0.068 0.092 0.447 0.308 REM 178 0.047 0.031 0.073 0.075 0.463 0.310 REM È È È È È È È È 835 0.049 0.023 0.049 0.078 0.517 0.284 REM 836 0.028 0.015 0.043 0.065 0.377 0.472 REM 837 0.039 0.010 0.026 0.044 0.407 0.474 W 838 0.106 0.003 0.059 0.042 0.540 0.251 W D違pi"603 vj吋"jk羽p"v益"n羽"e»pi"uw医v"ik英c"eƒe"f違k"u„pi"vjc{"8鰻k"v逢挨pi"泳pi"vjgq" eƒe"ikck"8q衣p"ik医e"pi栄0"雲"ikck"8q衣p"Yikƒ"vt鵜"Tbeta1 n "20747"*grqej"52+."ej泳pi"v臼"n¿e" p {"8嘘k"v逢嬰pi"8cpi"v雨pj"vƒq"x "v逢挨pi"泳pi"x噂k"ikck"8q衣p"Y0"A院p"grqej"vj泳"56."ikƒ"vt鵜"

Ralpha8衣v"2053;. n¿e"p {"8嘘k"v逢嬰pi"8cpi"荏"vt衣pi"vjƒk"pj逸o"o逸v"vj逢"ik«p."pj逢pi"x磯p" v pj"n "vt衣pi"vjƒk"vj泳e0"Ucpi"grqej"57."v益"n羽"e»pi"uw医v"e栄c"f違k"vjgvc"ejk院o"205;."x " ikck"8q衣p"v逢挨pi"泳pi"n "P30"A¿pi"x噂k"vk‒w"ejw育p"CUUỌ"vt衣pi"vjƒk"o "u„pi"vjgvc"zw医v" jk羽p"ecq"j挨p"u„pi"cnrjc"*jc{"ejk院o"j挨p"72'"grqej+"vj·"8逢嬰e"v pj"n "vj運k"8k吋o"8嘘k" v逢嬰pi"ej·o"x q"ik医e"pi栄."d逸v"8亥w"ikck"8q衣p"8亥w"vk‒p"e栄c"vt衣pi"vjƒk"P3 [5]. Ak隠w"p {" e pi"8逢嬰e"pj·p"vj医{"荏"grqej"74."75 x噂k"Ttheta n亥p"n逢嬰v"n "20728"x "20744. Quá trình

ejw{吋p"v瑛"ikck"8q衣p"P3"ucpi"P4"mj»pi"e„"ikƒ"vt鵜"p鰻k"vt瓜k"o員e"dù ikck"8q衣p"P4"8員e" vt逢pi"d荏k"u詠"zw医v"jk羽p"e栄c"vjqk"pi栄"*unggr"urkpfng+"jc{"rj泳e"d瓜"M."vw{"pjk‒p."eƒe"u„pi" 8員e"vt逢pi"p {"ej雨"zw医v"jk羽p"v瑛"o瓜v"8院p"jck"n亥p"trong 1 epoch. V·"vj院"p院w"uq"uƒpj"v益"n羽"

c„"o員v"e栄c"p„"uq"x噂k"eƒe"u„pi"e”p"n衣k"v衣k"épi"grqej."ikƒ"vt鵜"p {"u胤"mj»pi"vj吋"jk羽p"u詠"

n鰻k"vt瓜k"8員e"dk羽v"x "ejw{‒p"ikc"ik医e"pi栄"8隠w"f詠c"x q"j·pj"f衣pi"u„pi"8員e"vt逢pi"e栄c" ej¿pi"8吋"8ƒpj"pj«p"ikck"8q衣p"P4"j挨p"n "u穎"f映pi"v益"n羽"e»pi"uw医v0"Ejw{吋p"ucpi"ikck" 8q衣p"P5荏"grqej"vj泳"95."96."ikƒ"vt鵜"Tdelta8衣v"205;;"x "206:6."ikck"8q衣p"p {"8員e"vt逢pi" d荏k"u„pi"ej壱o"*u„pi"fgnvc+"ejq"ikck"8q衣p"pi栄"u¤w0"Ikck"8q衣p"TGO"v瑛"n¤w"8逢嬰e"pj壱p"

fk羽p"d荏k"v p"jk羽w"8k羽p"o逸v."vw{"pjk‒p"e„"vj吋"pj·p"vj医{."ikƒ"vt鵜"Ttheta và Rdelta ecq"j挨p"

các giƒ"vt鵜"e”p"n衣k"v衣k"eƒe"grqej"397"8院p"39:"*Ttheta > 0.44 và Rdelta > 0.25).

V瑛"d違pi"603"e„"vj吋"t¿v"tc"8員e"vt逢pi"v益"n羽"e»pi"uw医vjk羽w"sw違"ejq"d k"vqƒp"pj壱p" fk羽p"eƒe"ikck"8q衣p"ik医e"pi栄"d荏k"u詠zw医v"jk羽p"eƒe"u„pi"p«q"v逢挨pi"泳pi"vjgq"v瑛pi"ikck" 8q衣p"ik医e"pi栄"8逢嬰e"p‒w"tc"v瑛"vk‒w"ej "CCUO [5]. 4.3 M院v"sw違"ej丑p"n丑e"8員e"vt逢pid茨pi"vjw壱v"vqƒp"OTOT. Eƒe"8員e"vt逢pi"ucw"mjk"8逢嬰e"ej丑p"d茨pi"vjw壱v"vqƒp"OTOT"vjgq"vj泳"v詠"ikƒ"vt鵜" 8k吋o"u嘘"OTOT"ik違o"f亥p0"Vtqpi"swƒ"vt·pj"ej丑p"n丑ẹ"pj壱p"vj医{"v瑛"50 8員e"vt逢ng v瑛"v p" jk羽w"GGI"*m‒pj"E6+"x "v p"jk羽w"JTX"ik違o"e”p"20 8員e"vt逢pi"pj逢"d違pi"4.2. V逢挨pi"v詠." d違pi"4.3 vj吋"jk羽p"eƒe"43"8員e"vt逢pi"p鰻k"vt瓜k"v瑛"v p"jk羽w"GGI"*m‒pj"E5+"x "v p"jk羽w"

HRV. Nw壱p"x<p"u胤"f́pi"v鰻pi"j嬰r"eƒe"8員e"vt逢pi"e栄c"e違"4"m‒pj"E5"x "E6"8逢嬰e"ej丑p" v瑛"OTOT"8吋"vtƒpj"o医v"vj»pi"vkp"swcp"vt丑pi0"X·"vj院."u嘘"8員e"vt逢pi"v瑛"v p"jk羽w"GGI" ejq"4"m‒pj"n "6:"8員e"vt逢pị"o厩k"m‒pj"46"8員e"vt逢pi"GGI"x "4"8員e"vt逢pi HRV.

D違pi"4.2: A員e"vt逢pi"p鰻k"vt瓜k"x "ikƒ"vt鵜"OTOT"v逢挨pi"泳pi"*m‒pj"E6+. 0.12

A員e"vt逢pi"

p鰻k"vt瓜k O»"v違 OTOT"Ikƒ"vt鵜"

G49 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"3"x "vjgvc"*G;"x "G34+" 20596 G56 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"vjgvc"x "fgnvc"*G34"x "G35+ 20575 G72 Rj鰻"p<pi"n逢嬰pi"NH"e栄c"JTX" 2042; G52 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"urkpfng"x "vjgvc"*G32"x "G34+ 20426 G: Ikƒ"vt鵜"vtwpi"d·pj"ikƒ"vt鵜"vw{羽v"8嘘k"eƒe"j羽"u嘘"Ycxgngv"vtqpi"f違k"dgvc"4 203;8 G64 Vtwpi"d·pj"mjƒe"dk羽v"vw{羽v"8嘘k"*OCF+"e栄c"o厩k"grqej 203:9 G44 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"4"x "cnrjc"*G:"x "G33+" 203:7 G; Ikƒ"vt鵜"vtwpi"d·pj"ikƒ"vt鵜"vw{羽v"8嘘k"eƒe"j羽"u嘘"Ycxgngv"vtqpi"f違k"dgvc"3 203:6 G37 A瓜"n羽ej"ejw育p"e栄c"eƒe"j羽"u嘘"Ycxgngv"vtqpi"f違k"dgvc"3" 203:5 G66 V益"n羽"e»pi"uw医v"f違k"dgvc"3 20393 G4: V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"3"x "fgnvc"*G;"x "G35+" 20373 G34 Ikƒ"vt鵜"vtwpi"d·pj"ikƒ"vt鵜"vw{羽v"8嘘k"eƒe"j羽"u嘘"Ycxgngv"vtqpi"f違k"vjgvc 20366 G54 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"cnrjc"x "vjgvc"*G33"x "G34+" 20365

G69 V益"n羽"e»pi"uw医v"f違k"vjgvc 20355 G42 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"4"x "dgvc"3"*G:"x "G;+" 20354 G46 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"4"x "fgnvc"*G:"x "G35+" 20343 G47 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"3"x "urkpfng"*G;"x "G32+" 20343 G55 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"cnrjc"x "fgnvc"*G33"x "G35+" 2033: G45 V益"n羽"ikƒ"vt鵜"vw{羽v"8嘘k"vtwpi"d·pj"ik英c"dgvc"4"x "vjgvc"*G:"x "G34+" 20337

D違pi"4.3: A員e"vt逢pi"p鰻k"vt瓜k"x "ikƒ"vt鵜"OTOT"v逢挨pi"泳pi"*m‒pj"E5+. 0.13

A員e"vt逢pi"

p鰻k"vt瓜k O»"v違 OTOT"Ikƒ"vt鵜"

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E映"vj吋"pj逢"ucw<"

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N1+N2+R và W.

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hình 4.8, c„"vj吋"vj医{"8員e"vt逢pi"8逢嬰e"ik違o"x "v壱r"vtwpi"vjgq"e映o"pjk隠w"j挨p"uq"x噂k"n¿e

x "n "d逢噂e"8吋"z¤{"f詠pi"o»j·pj"vt‒p"pj英pi"8員e"vt逢pi"8«"8逢嬰e"ej丑p"n丑e"rj́"j嬰r"x噂k" eƒe"8嘘k"v逢嬰pi"vjw瓜e"d瓜"f英"nk羽w"3.

4.4 M院v"sw違"rj¤p"e映o"d茨pi"M-means clustering.

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- Ej雨"u穎"f映pi"4"8員e"vt逢pi"v瑛"v p"jk羽w"GGI: v益"n羽"e»pi"uw医v"e栄c"u„pi"Cnrjc"x "

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và 7"e映o0Piq k"tc."d違pi"606"ejq"vj医{"mj違"p<pi"rj¤p"nq衣k"5"e映o"8衣v"jk羽w"sw違"v嘘v"j挨p" uq"x噂k"eƒe"nq衣k"rj¤p"e映o"mjƒe0"O員e"f́"rj¤p"vj pj"4"e映o"8衣v"8瓜"ej pj"zƒe"ecq"pj逢pi" n衣k"mj»pi"e„"#"pij c"vtqpi"rj¤p"nq衣k"8栄"eƒe"ikck"8q衣p"ik医e"pi栄"e亥p"vjk院v0"X·"vj院."rj¤p" 5"e映o"f英"nk羽w"n "rj́"j嬰r"ejq"d k"vqƒp"rj¤p"nq衣k"ejq"8ƒpj"ikƒ"eƒe"vj»pi"u嘘"ik医e"pi栄0

D違pi"4.4: M院v"sw違"rj¤p"e映o"vjgq"n噂r"d茨pi"vjw壱v"vqƒp"M-means clustering. 0.14

Rj¤p"nq衣k" 7"e映o" 6"e映o 5"e映o 4"e映o

A瓜"ej pj"zƒe (%) 23.15 32.82 59.31 74.94

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0.106 Hình 4.9: O»"vV"mjV"p<pi"rj¤p"5"eつo"vt‒p"mj»pi"ikcp"jckejkzw"djpi"vjwfv"vqƒp"

K-means clustering

O»"vV"mjV"p<pi"rj¤p"5"eつo"vt‒p"mj»pi"ikcp"jck ejkzw"djpi"vjwfv"vqƒp"

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4.5 M院v"sw違"rj¤p"nq衣kd茨pi"UXO"qpg"xu all.

4.503"M院v"sw違"rj¤p"nq衣k"jk羽w"uw医v"e栄c"UXO"Ðone vs allÑvt‒p"pjk隠w"n噂r.

D違pi 4.5: Jk羽w"uw医v"rj¤p"nq衣k"e栄c"UXO"Ðqpg"xu"cnnÑ"vt‒p"pjk隠w"n噂r. 0.15 Ikck" 8q衣p Y P3 7"n噂rP4" P5" TGO Y P3-P4"6"n噂rP5" TGO Rtgekukqp 76.81 24.57 82.68 77.47 72.75 82.57 80.85 72.87 63.57 Tgecnn 77.40 59.95 71.61 65.52 68.80 74.04 77.77 86.03 75.74 H3/ueqtg 77.10 34.85 76.75 70.99 70.72 78.07 79.28 78.91 69.13 Ceewtce{ 70.78 77.54 Ikck"

8q衣p Y" P3-P4-TGO5"n噂r P5 Y" PTGO5"n噂r TGO Vj泳e4"n噂rPi栄

Rtgekukqp 80.10 89.04 72.98 81.46 86.88 62.67 70.26 95.79

Tgecnn 75.38 88.08 86.13 74.23 86.36 75.64 82.64 91.87

H3/ueqtg 77.67 88.56 79.01 77.68 86.62 68.55 75.95 93.79

Ceewtce{ 84.81 82.03 90.13

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- Rj¤p"nq衣k"7"n噂r< accuracy 8衣v"70.78%, precision và recall v衣k"n噂r"P3"n亥p"n逢嬰v"n

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nq衣k"6"n噂r"8衣v"99.54'."eƒe"vj»pi"u嘘"ikƒ"vt鵜"cho các gkck"8q衣p"mjƒe"pjcw"8隠w"p茨o"v瑛"

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4.5.2 V鰻pi"u嘘"grqej"u穎"f映pi"vtqpi"rj¤p"nq衣k.

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macro F1-ueqtg"d荏k"u詠"ej‒pj"n羽ej"ik英c"eƒe"n噂r"f英"nk羽w0"

4.505"M院v"sw違"8ƒpj"ikƒ"m院v"sw違"u穎"f映pi"oc"vt壱p"pj亥o"n磯p.

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