yehudah s role in the revival of hebrew as a vernacular
Play and it’s role in the mental development of the child
Ngày tải lên :
23/06/2014, 09:52
... that stresses the fact that these girls are sisters: they are dressed alike, they walk about holding hands – in short, they enact whatever emphasizes their relationship as sisters visa-vis adults ... from situational constraints The first paradox of play is that the child operates with an alienated meaning in a real situation The second is that in play he adopts the line of least resistance, ... expressed as a fraction in which the object is the numerator and the meaning is the denominator; this expresses the particular relationship of object and meaning that arises on the basis of speech...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
Ngày tải lên :
18/02/2014, 04:20
... Emerging roles for proteinases in cancer Invasion Metastasis 17, 221–239 Ellerbroek SM & Stack MS (1999) Membrane associated matrix metalloproteinases in metastasis Bioessays 21, 940–949 Sato ... between the MT1-MMP ICD and GRASP55 using a mammalian two-hybrid (M2H) system Using this approach, we have identified the GRASP55 binding site in the ICD of MT1-MMP, as well as the GRASP55 domains involved ... proprotein-convertase was found in the same complex as MT1-MMP (Fig 9A, lane 2, asterisk) Expression of GRASP55F together with furin resulted in a significant increase in the amount of furin co-immunoprecipitated...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
Ngày tải lên :
19/02/2014, 06:20
... B is expressed widely in human tissue and is thought to act as an inhibitor of the lysosomal cathepsins Alternative functions are possible, as the protein was found as part of a multiprotein ... v2 values and obtain best fit parameters for the association constants, Ka, and the change in enthalpies, H° In all cases best fit parameters were obtained from the sequential binding sites model, ... Rinne R, Theol G, Haan G, Lindhout D, Salmikangas P, Saukko P, Lahtinen U & Lehesjoki A (2004) Loss of lysosomal association of cystatin b proteins representing progressive myoclonus epilepsy,...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
Ngày tải lên :
21/02/2014, 01:21
... amount of a- L-1,3-arabinofuranosidase was responsible for the disappearance of Fig HPAEC analysis of the hydrolysis of arabinogalactans by GALA Three different arabinogalactans were used: potato ... D-galactose and 38% L-arabinose Methylation analysis demonstrated that a substantial amount of the L-arabinose residues (14%) in soy arabinogalactan is present as terminal residues [21], suggesting ... arabinogalactan consists of 99% D-galactose and 0.3% L-arabinose and is predominantly linear Potato arabinogalactan consists of 86% D-galactose and 6.6% L-arabinose, while soy arabinogalactan consists of 57%...
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Báo cáo Y học: Functional expression of human liver cytosolic b-glucosidase in Pichia pastoris Insights into its role in the metabolism of dietary glucosides ppt
Ngày tải lên :
08/03/2014, 16:20
... amount of reCBG in the supernatant was estimated by activity measurement assays using 4NPGlc as substrate Expression of cbg-1 in P pastoris and isolation of reCBG Large-scale expression was achieved ... at 37 °C, and measuring the release of 4NP Protein assays and protein sequencing Total protein in crude and semipuri®ed samples was estimated using the Pierce Protein Assay Reagent with BSA as ... dihydrochalcones such as phlorizin (abundant in apple skins), anthocyanodins such as kuromanin (red wine, grape skins and seeds, berries, raspberries, strawberries) and secoiridoids such as oleuropein (olives)...
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Báo cáo khoa học: Characterization of Trypanosoma brucei PEX14 and its role in the import of glycosomal matrix proteins pptx
Ngày tải lên :
23/03/2014, 17:21
... cells were incubated for at concentrations of digitonin as indicated The release of PYK, ALD, GAPDH and TIM from the cells was assayed after centrifugation of the treated cell suspensions and the ... hemocyanin, was used to raise a polyclonal antiserum in rabbit The specificity of the antiserum was checked using a Western blot prepared after SDS/PAGE with a lysate of E coli cells expressing ... considered as a valid and highly appropriate target for the design of trypanocidal drugs, because this process is of vital importance for the energy supply of the parasites and the sequestering of their...
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Differences by Mother''''s Education in the Effect of Childcare on Child Obesity pdf
Ngày tải lên :
30/03/2014, 05:20
... are assumed to be linearly related to child s weight status As a measure of child s weight status, which enters as a dependent variable in the models, the studies either use a continuous measure ... childcare setting Finally, for a child whose mother has at least a bachelors degree, the probability of obesity steadily increases substantially as the child spends more time in a non-parental childcare ... unit and his wife In each wave of the PSID the respondent was asked about his/her current employment status If the status was “working now”, then the respondent was asked the question about the...
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Báo cáo khoa học: Acylation of lysophosphatidylcholine plays a key role in the response of monocytes to lipopolysaccharide ppt
Ngày tải lên :
31/03/2014, 01:20
... This suggests that the signaling pathway from the IFN-c receptor to the acyltransferase involves tyrosine kinases but not protein kinase C Such a finding is not unexpected as the Janus family of ... acyltransferase inhibitors SK&F 98625, originally described as a CoA-independent acyltransferase inhibitor [16], was included as it inhibits both LPCAT and LPAAT in MonoMac cells with IC50 values of ... other acyltransferases) is a key regulator of both the priming of monocytes by IFN-c and for LPS-initiated TNF -a release Materials and methods Materials Unless stated otherwise, all reagents...
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Báo cáo khoa học: "SemiPro-inflammatory cytokines play a key role in the development of radiotherapy-induced gastrointestinal mucositis" pptx
Ngày tải lên :
09/08/2014, 08:22
... conduction of the real-time PCR and assisted in manuscript preparation AMS participated in the study design, assisted in the animal studies, performed data analysis and assisted in manuscript preparation ... assisted in the animal studies, performed data analysis and was responsible for the overall manuscript preparation JMB participated in the study design, assisted in the animal studies, assisted in the ... TNF All tissue sections were assessed for the submucosal protein expression of IL-1b, IL-6 and TNF There was no apparent submucosal staining in the vast majority of sections Occasional sections...
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Báo cáo y học: "Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration" ppt
Ngày tải lên :
09/08/2014, 10:20
... Multivariate linear regression adjusted for age (using Stata statistical package; StataCorp LP, College Station, TX, USA) was used to assess the association between MTL and IVD degeneration Mann-Whitney ... for each passage, and cumulative population doublings were calculated At each passage, an aliquot of approximately × 106 cells was taken for analysis of MTL, and regression analysis and Spearman ... telomerase reverse transcriptase) gene expression Human telomerase reverse transcriptase polymerase chain reaction Reverse transcriptase-polymerase chain reaction (PCR) was used to investigate the gene...
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báo cáo khoa học: " The transcription factor PHR1 plays a key role in the regulation of sulfate shoot-to-root flux upon phosphate starvation in Arabidopsis" potx
Ngày tải lên :
11/08/2014, 11:21
... functional role of PHR1 in sulfate homeostasis was assessed by examining the root-to-shoot and shoot-to-root sulfate transfer in the phr1 mutant in comparison to the sultr1;3 and sultr2;1 single mutants ... g) These results indicate that the expression of SULTR1;3, SULTR3;4 and SQD1 was regulated at least partially by the local tissue Pi content instead of a systemic signal initiated in the roots ... Kataoka T, Hayashi N, Yamaya T, Takahashi H: Root-to-shoot transport of sulfate in Arabidopsis Evidence for the role of SULTR3;5 as a component of low-affinity sulfate transport system in the root...
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Báo cáo y học: " Th2 cytokines and asthma Interleukin-4: its role in the pathogenesis of asthma, and targeting it for asthma treatment with interleukin-4 receptor antagonists" pot
Ngày tải lên :
12/08/2014, 18:20
... administration of IL-4 to patients with mild asthma resulted in a significant increase in airway hyperresponsiveness that was associated with the elevation of sputum eosinophil numbers [17] A variety of findings ... T, Kawai M, Sasaki S, Dake Y, Hamasaki N, Shirakawa T, Hopkin JM: α Ile50Val variant of IL4Rα upregulates IgE synthesis and associates with atopic asthma Nat Genet 1998, 19:119–120 35 Hershey ... cells with IL-4 downregulates Fas expression on the cell surface The expression of IL-4 in the asthmatic lung and the secondary lack of Fas expression might explain the persistence of inflammatory...
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Báo cáo y học: "Pro/con debate: Octreotide has an important role in the treatment of gastrointestinal bleeding of unknown origin" pptx
Ngày tải lên :
12/08/2014, 23:24
... current setting, based on published efficacy data, let alone cost considerations Somatostatin or octreotide can be considered in patients with NVUGB on a case-by-case basis, as additional pharmacotherapy, ... bleeders seen [28] Because of their effect on decreasing portal pressure, somatostatin and analogues have been used in acute variceal bleeding In this patient population, metaanalyses [29] have shown ... Thomopoulos KC, Katsakoulis EC, Vasilopoulos AG, Margaritis VG, Vagianos CE: The effect of octreotide as an adjunct treatment in active nonvariceal upper gastrointestinal bleeding J Clin Gastroenterol...
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HUMAN CARBOXYLESTERASE 2 SPLICE VARIANTS: EXPRESSION, ACTIVITY, AND ROLE IN THE METABOLISM OF IRINOTECAN AND CAPECITABINE
Ngày tải lên :
24/08/2014, 12:18
... protein assays, and activity assays Dr Paresh Sanghani completed the CD analysis CPT-11 hydrolysis assay The CPT-11 hydrolysis assay has previously been described by Sanghani et al (2004) In 250 ... exogenous compounds as well as the activation of prodrugs (Satoh and Hosokawa, 1998) Catalyzing phase I hydrolysis reactions, carboxylesterases can increase the polarity of an exogenous substrate ... hydrolases are described at the ESTHER database (Hotelier et al., 2004) Carboxylesterases catalyze the hydrolysis of esters, thioesters, carbamates, and amides Endogenous substrates of carboxylesterases...
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Co-relationship between teacher-related factors and student's motivation in the context of Lomonoxop school, Hanoi = Quan hệ tương hỗ giữa yếu tố giáo viên và đ
Ngày tải lên :
28/03/2015, 09:42
... with another language studied Hence, the the second/foreign language learning was seen as a threat to the mastery of this other language, which was considered easier and more useful in any case ... of structure and or detail Also, there were conflicts about the degree of closure or seriousness of the class The nature of classroom activities was the fourth theme It included aspects such as, ... is measured in such aspects as his or her carefulness in lesson preparing, enthusiasm for teaching, love for students, thorough explanation of language matters to students, willingness to answer...
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Báo cáo khoa học: Transcriptome profiling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet pdf
Ngày tải lên :
16/03/2014, 04:20
... enhanced in animals exposed to an HFD with GBE50 Genes involved in fatty acid biosynthesis, such as Acacb, Acbd6 (acyl-CoA-binding domain containing 6), Scd2 (stearoyl-CoA desaturase 2) or associated ... no significant alterations in the levels of alanine aminotransferase, aspartate aminotransferase or creatinine kinase in either group H or group HG (Table 1) However, serum triglyceride levels ... (a) the signal of log ratios in the control group was significantly variable, as detected by a one-class comparison (setting false discovery rate = 0.01) using the software sam 2.20 [32]; (b) the...
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Evidence based Psychological Interventions in the Treatment of Mental Disorders A Literature Review
Ngày tải lên :
02/06/2014, 09:39
... NS NS NS NS NS NS NS NS NS NS NS NS NS NS Psychotic disorders NS NS NS NS NS NS NS NS NS NS NS NS NS NS Body dysmorphic NS NS NS NS NS NS NS NS NS NS NS NS NS NS Hypochondriasis NS NS NS NS NS NS NS NS NS NS NS NS NS NS Somatisation ... as a necessary measure of the success of an intervention has been that in the real world the treatment setting is never as controlled as in RCT conditions This has led to the debate between studies ... interventions with a large or increasing evidence base: Databases used in search for relevant studies The literature review was conducted using searches of three databases: > the Cochrane Library –...
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Báo cáo hóa học: " Enabling direct connectivity between heterogeneous objects in the internet of things through a network-service-oriented architecture" docx
Ngày tải lên :
21/06/2014, 01:20
... the following • Location awareness is increasingly important This includes awareness of the personal surroundings, the tracking and positioning of objects, as well as support for user and object ... mechanisms to easily associate metadata with content, such as the originating location, information about the producer of the content and the content description This metadata should also be included ... regards to the internet of things, SOAs have two main disadvantages [32]: (1) SOAs focus mainly on higher layers rather than solving network issues and (2) the technologies used to realize service-oriented...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
Ngày tải lên :
08/08/2014, 23:21
... been stabilised and then maintained for at least weeks It is also approved as an adjunct agent for the treatment of depression The mechanism of action of aripiprazole differs both from FGAs as well ... reaction (such as swelling in the mouth or throat, itching, rash), speech disorder, agitation, fainting, transaminasaemia, pancreatitis, muscle pain, stiffness, or cramps and very rarely neuroleptic ... efficacy of aripiprazole against acute mania and they report that the separation from placebo occurred as early as days to They also provide some support for its efficacy against mixed episodes and...
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Báo cáo khoa học: "Helical tomotherapy in the treatment of pediatric malignancies: a preliminary report of feasibility and acute toxicitty" doc
Ngày tải lên :
09/08/2014, 09:21
... Data are presented as mean ± SD or as a range of mean PTV dose § Data are presented as median (range) for groups and as single values for individual cases † Data are presented as irradiation ... Laskar S, Bahl G, Muckaden M, Pai SK, Gupta T, Banavali S, Arora B, Sharma D, Kurkure PA, Ramadwar M, Viswanathan S, Rangarajan V, Qureshi S, Deshpande DD, Shrivastava SK, Dinshaw KA: Nasopharyngeal ... understood, and a quantitative risk assessment still has a lot of uncertainties [37], in absence of an accurate risk model, prospective recording of dosimetrical data seems necessary to evaluate the...
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