... (JacksonImmuno-Research, West Grove, PA) and visualization withan ECL kit (Amersham Pharmacia Biotech, Piscataway, NJ).Statistical analysisResults are expressed as means ± SE. Statistical analysiswas carried ... the finding that in hepatocytes, unlike in muscle, inactivation of phosphorylase rather thaninactivation of glycogen synthase kinase-3 is a majorcomponent of the mechanism by which insulin stimu-lates ... Chicago, IL, USA3 Cardiovascular and Gastrointestinal Discovery – AstraZeneca Pharmaceuticals, Macclesfield, UKType 2 diabetes is associated with impaired glucose-induced insulin secretion and...
... tensile load causes animbalance between matrix metalloproteinases (MMPs)and tissue inhibitors of matrix metalloproteinases(TIMPs), and an increases of the expressionof proinflam-matory cytokines ... results in an increase of Col X mRNA expression. Such quantitative analysis hasimportant implications for our understanding of mechanosensitivity of cartilage and mechanicalregulation of chondrocyte ... IL,USA) and exposing the membrane to Kodak X-Omat ARDistribution of surface strains ina typical sponge (4.3% overall strain in this example)Figure 3Distribution of surface strains ina typical...
... ear-lywood density followed an oscillating pattern of variation. In their study of families of radiata pine established in several sites in New Zealand, Cown and Ball [8] also measured average ... Vargas-Hernandez [34]observed that area weighted ED and LD increased with cambialage in 60 families of coastal Douglas-fir that were analyzed atage 15. A similar pattern was reported by Wang ... south of ChileFrancisco ZAMUDIO a *, Philippe ROZENBERGb, Ricardo BAETTIG a , Adriana VERGARA a , Marco YAÑEZ a , Carlos GANTZc a Facultad de Ciencias Forestales, Universidad de Talca, PO...
... Ihara-Selberg zeta function ofa hypergraph,and gave two determinant expressions of it by the Perron-Frobenius operator of a digraph and a deformation of the usu al Laplacian ofa graph . We present a newdeterminant ... journal of combinatorics 16 (2009), #R132 5 A new determinant expressionof the zeta functionfor a hypergraphIwao SatoOyama National College of Technology,Oyama, Tochigi 323-0806, Japanisato@oyama-ct.ac.jpSubmitted: ... definedzeta functions of graphs, and showed that the reciprocals of zeta functions of regulargraphs are explicit polynomials. A zeta function ofa regular graph G associated with a unitary representation...
... primerswere as follows: for β-actin, 5'-GTGGGGCGCCCCAGG-CACCA-3' and 5'-CTCCTTAATGTCACGCACGATTTC-3' ; for SOCS1, 5'-AGACCCCTTCTCACCTCTTG-3' and5'-GCACAGCAGAAAAATAAAGC-3' ... Sunahori and Hirofumi MakinoDepartment of Medicine and Clinical Science, Graduate School of Medicine and Dentistry, Okayama University, Okayama, JapanCorresponding author: Masahiro Yamamura, yamamura@md.okayama-u.ac.jpReceived: ... arthritis. Arthritis Rheum 1997, 40:1096-1105.28. Okamoto A, Yamamura M, Iwahashi M, Aita T, Ueno A, KawashimaM, Yamana J, Kagawa H, Makino H: Pathophysiological func- Arthritis Research & Therapy...
... the electronic journal of combinatorics 4 (1997), #R3 4ratioofthetwoversionsofλapproach 1, the inequality in (2) follows from that in (1) by replacing B with the average of B and 1 − b.Let d = ... assume that k ≥ k0= n/2.(5) the electronic journal of combinatorics 4 (1997), #R3 21. IntroductionAlmost all the familiar concepts of linear algebra, such as dimension and linearindependence, ... elements. Because the underlying field is finite, there aremany counting problems associated with fundamental concepts of linear algebra;for example, how many subspaces of dimension k are there in the...
... effectiveness of state laws, and lack of harmonization at the international level a number of states have started to block access to websites and social media platforms that allegedly contain illegal ... participating States”, “make it their aim to facilitate the freer and wider dissemination of information of all kinds” and “encourage co-operation in the field of information and the exchange ... States, such as Belarus, Croatia, Lithuania, Poland and Turkey, require filtering software to be used in academic institutions, libraries and Internet cafes. In other states, such as Canada,...
... size of amplified message. DNA l adder is marked M. (A) HaCaT keratinocytes (lane 1); normal epidermal keratinocytes (lane 2); C1–4 squamous cell carcinoma (lane 3); dermal fibroblasts (lane 4);epidermal ... (lane 9). (C)HaCaT keratinocytes (lane 1); normal epidermal keratinocytes (lane 2); C1–4 squamous cell carcinoma (lane 3); dermal fibroblasts (lane 4);epidermal melanocytes (lane 5); melanoma ... ndicating pathwayactivation in vivo, at least under pathological conditions.Epidermal availability of 7-DHC in conjunction with thepresence of an active P450scc system makes it probable that7-DHP...
... and lung cancer.Immunostaining of prostate cancer tissue with antibodies against AMACR and PSAFigure 2Immunostaining of prostate cancer tissue with antibodies against AMACR and PSA. Surgically ... AbstractAlpha-methylacyl-CoA racemase (AMACR) is an enzyme playing an important role in the beta-oxidation of branched-chain fatty acids and fatty acid derivatives. High expression levels of ... of PBS containing 1% for-maldehyde, and analyzed by FACScan (Becton Dickinson,Mountain View, CA). Binding affinity was evaluated bycomparing mean fluorescence intensity (MFI) of HLA- A2 4 expression...
... ERCC1and XRCC1 and radioresistance in laryngeal tumors[33].Cetuximab is an IgG1 monoclonal antibody againstthe ligand-binding domain of EGFR. Cetuximab bindsTable 3 Univariate analyses of prognostic ... Chemotherapy added tolocoregional treatment for head and neck squamous-cell carcinoma:three meta-analyses of updated individual data. MACH-NC CollaborativeGroup. Meta-Analysis of Chemotherapy on ... value of the Hscore was chosen as the cutoff point for separating lowand high levels of ERCC1 expression [22].Statistical analysisStatistical analyses of 2 ì 2 tables of categorical variableswere...
... Her2 (a, membranous staining and Her3 (b, membranous andcytoplasmic staining, and c, predominant cytoplasmic staining) 400 ì magnification.Takikita et al. Journal of Translational Medicine 2011, ... differentiation, migration,proliferation, and survival.Her2 has an extracellular domain, but appears to lackligand-binding activity, while Her3 has a non-functionalkinase domain and has no catalytic ... structure, with an extracellularligand-binding domain, a transmembrane domain, andan intracytoplas mic tyrosine kinase domain[3-5]. Ligandbinding to these receptors induces the formation of * Correspondence:...
... ERCC1and XRCC1 and radioresistance in laryngeal tumors[33].Cetuximab is an IgG1 monoclonal antibody againstthe ligand-binding domain of EGFR. Cetuximab bindsTable 3 Univariate analyses of prognostic ... Chemotherapy added tolocoregional treatment for head and neck squamous-cell carcinoma:three meta-analyses of updated individual data. MACH-NC CollaborativeGroup. Meta-Analysis of Chemotherapy on ... P, Papakostas P, et al: Inductionchemotherapy with docetaxel and cisplatin followed by concomitantchemoradiotherapy in patients with inoperable non-nasopharyngealcarcinoma of the head and...
... Her2 (a, membranous staining and Her3 (b, membranous andcytoplasmic staining, and c, predominant cytoplasmic staining) 400 ì magnification.Takikita et al. Journal of Translational Medicine 2011, ... migration,proliferation, and survival.Her2 has an extracellular domain, but appears to lackligand-binding activity, while Her3 has a non-functionalkinase domain and has no catalytic activity. ... Program, Laboratory of Pathology, National CancerInstitute, National Institutes of Health, Bethesda, MD 20892, USA.2AppliedMolecular Pathology Laboratory, Laboratory of Pathology, National CancerInstitute,...