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... analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasisrelated proteins J ... analysis Statistical analysis was performed by Student s t test Statistical tests were two-sided at the 5% level of significance Pearson s correlation coefficient, p-value (p) and ANOVA with post ... Flow cytometric analysis of plasma membrane exposure of phosphatidylserine (detected using an annexin VFITC assay) was used as an index of apoptotic (annexinpositive) versus necrotic (PI positive)...

Ngày tải lên: 18/06/2014, 19:20

... analysis of gastric cancer metastasis by two-dimensional gel electrophoresis and matrix assisted laser desorption/ionization-mass spectrometry for identification of metastasisrelated proteins J ... analysis Statistical analysis was performed by Student s t test Statistical tests were two-sided at the 5% level of significance Pearson s correlation coefficient, p-value (p) and ANOVA with post ... Flow cytometric analysis of plasma membrane exposure of phosphatidylserine (detected using an annexin VFITC assay) was used as an index of apoptotic (annexinpositive) versus necrotic (PI positive)...

Ngày tải lên: 20/06/2014, 03:20

... bone biopsy was recommended to differentiate PDB from secondary tumors such as metastases from prostate cancer or breast cancer, and other sclerosing bone dysplasia [2,3] To monitor disease activity ... Recently, several studies have indicated the possibility that long-term or high-dose bisphosphonate therapy could cause severe side effects, including osteonecrosis of the jaws [12,13], or lead to severe ... effects of treatment, we measured T-ALP and uNTX levels of our patients every three to six months and assessed their bone pain as described in previous studies [1,3,11,15] In both of our patients,...

Ngày tải lên: 11/08/2014, 12:20

... We used the CostIt [19] spreadsheet to categorize and summarize data of hospital costs, and SPSS 14.1 software for statistical analysis of patient data Results Unit costs Table shows the direct, ... unit costs of HIV-related hospital services for the base year 2004/5 CD4 test was the most expensive HIV-related service (cost, US$6.8 per unit) whereas other laboratory tests (e.g., stool, sputum, ... constant for all types of test 2Unit costs of inpatient services are expressed as costs per inpatient days Table 2: Average annual per patient use (95% CI) of hospital services by ART and AIDS status...

Ngày tải lên: 13/08/2014, 11:22

... injections disappearing later but sometimes steroids were given to alleviate the symptoms In other cases rheumatoid arthritis or osteoarthritis proved to be the cause of these symptoms During ... the original RAST [6] so that the conversion factor from this study was used The DPC AlaStat method has in unpublished data in-house shown to be comparably sensitive to CAP It is estimated that ... indefinitely Such selection is difficult According to other studies the following symptoms and signs have been found to be risk factors for experiencing SAR at a future sting after cessation of...

Ngày tải lên: 13/08/2014, 13:22

... compression SCI models In contusive SCI transplantation studies, SCs have been shown to survive most effectively when delayed to to 10 days post-SCI instead of directly into the inhospitable setting ... instructions Quantification of detected bands was performed by densitometry using ImageJ software (NIH) Histological Assessments Six weeks post-injury, tissue was collected and processed as previously ... or transversely at 20 μm thickness on Superfrost Plus slides (Fisher Scientific) using a cryostat (Leica) Tissue was stained using cresyl violet acetate stain with eosin counterstaining Lesion...

Ngày tải lên: 24/08/2014, 09:14

... chymotrypsin of the three strands encompassing residues 40–82, in spite of the relative abundance of residues sensitive to this protease Most of these hydrophobic residues are pointing inwards in ... 0.15 mM BLG, respectively To test this possibility in a simple way, we performed assays in which native BLG was added to a protease assay mixture containing synthetic substrates at 37 °C and ... chromatograms presented in Fig Analysis of the proteolyzed samples by SDS/PAGE (data not shown) was consistent with the figures reported in Table The extensive proteolysis observed with chymotrypsin...

Ngày tải lên: 21/02/2014, 15:20

... the socio-dental approach for oral health needs assessment [12-14] Although using condition-specific OHRQoL measures for needs assessment seems theoretically sound, some recent studies have also ... Class II and Class III buccal occlusions, and hypodontia Only the highest scoring trait is used to assess treatment need [29] Thereafter, adolescents self-rated their dental attractiveness on ... cases were therefore classified as having no need For DAI, 10 occlusal traits were assessed and a score was obtained using the equation: 6×(missing visible teeth) + crowding + spacing + 3×(diastema)...

Ngày tải lên: 18/06/2014, 19:20

... Karolinska Universitetssjukhuset, Solna; prof Fredrikson, Karolinska Universitetssjukhuset, Huddinge; dr Martin, Danderyds sjukhus, Stockholm; dr Svenningsson, Norrlands Universitetssjukhuset, ... correlation to EDSS [27] EDSS was assessed at baseline LMS-QoL, FIS and BDI-SF were completed by patients at home within days before study visit or at the clinic just prior to the visit Investigators completed ... Belgium Outcome measures and assessments HR-QoL was assessed by the Leeds Multiple Sclerosis Quality of Life (LMS-QoL) scale In 2000 the LMS-QoL scale was developed in a community-based population...

Ngày tải lên: 20/06/2014, 15:20

... depression to analyze the impact of overall residual symptom levels as well as specific residual depressive symptom clusters on depressive recurrence Both residual anxiety and residual sleep disturbance ... risk of subsequent relapse, the present study is the first to be specifically designed to identify predictors of relapse in MDD In summary, the results of the present analysis not suggest that a ... basis to develop better treatment options and to improve MDD outcome [4] Several studies published to date suggest that sleep disturbance, namely insomnia and hypersomnia, may represent such symptoms...

Ngày tải lên: 08/08/2014, 23:21

... Statistical analysis Statistical analysis and calculations were performed using SPSS 13.00 software (SPSS Institute Inc., Cary, NC, USA) Because of differences in baseline characteristics, predictive ... before infusions All adverse events, including infusion reactions, were registered and seriousness graded by one investigator Grades of seriousness were as follows: mild, moderate, serious and life ... biologics [18] The evaluations included swollen and tender joint counts, assessment of pain (visual-analogue scale), patient overall assessment (visual-analogue scale), physician 's global assessment...

Ngày tải lên: 09/08/2014, 08:22

... patients in Study selfidentified as East and Southeast Asians Weight changes In all studies, patients experienced statistically significant (p

Ngày tải lên: 11/08/2014, 16:22

... patients Assessments Efficacy measures included the change in the Positive and Negative Syndrome Scale (PANSS) total score, PANSS positive, PANSS negative, and PANSS general psychopathology scores ... of dyskinetic movements, and used as the primary measure to assess the incidence of tardive dyskinesia (TD) The Barnes Akathisia Scale 18 was used to assess akathisia at baseline and during treatment ... Time to early discontinuation was assessed by the Kaplan-Meier method and log rank test Analyses of the change from baseline in efficacy rating scales (PANSS total, PANSS positive, PANSS negative,...

Ngày tải lên: 11/08/2014, 16:22

... donors (n = 10) were included as controls The Wilcoxon matched pairs test and the Mann-Whitney test of SPSS version 12.0 were used to assess differences among groups Spearman correlation analysis ... cells as well as on HBV-specific CD8 T cells in CHB patients It is widely accepted that CD8 T cells play an essential role in the immune response to viral infection In successful responses to ... non-responders These comparison results obtained in the responders and non-responders to antiviral therapy support the notion that increased expression of CD127 on memory CD8 T cells is linked to successful...

Ngày tải lên: 12/08/2014, 01:21

... rheumatoid arthritis; SLE: systemic lupus erythematosus; SoJIA: systemic-onset juvenile idiopathic arthritis; SpA: spondyloarthritis; SS: Sjögren syndrome; TNF: tumor necrosis factor van Baarsen ... 76:528-537 Sigurdsson S, Nordmark G, Garnier S, Grundberg E, Kwan T, Nilsson O, Eloranta ML, Gunnarsson I, Svenungsson E, Sturfelt G, Bengtsson AA, Jonsen A, Truedsson L, Rantapaa-Dahlqvist S, Eriksson ... patients with those of healthy controls and found that a subgroup of RA patients has an increased expression of type I IFN response genes [13] This increased expression in IFN response genes was highly...

Ngày tải lên: 12/08/2014, 11:22

... modes, the endovascular approach developed in recent years has fewer risks and significantly less trauma to patients, as demonstrated in previous studies as well as the present study Occlusion ... progressive arterial stenosis When the area is completely occluded, the artery appears as a “beak” shape on DSA images The progression is quite slow and difficult to diagnose 16 In the present case, ... similar clinical syndromes as that caused by atherosclerosis, so it is also a possible diagnosis However, DSA images can discriminate between the two cases: an occlusion at the beginning part...

Ngày tải lên: 25/10/2012, 11:04

Ngày tải lên: 13/02/2014, 12:20

... against their cytotoxicity Hsp27 is less effective than Hsp70 ⁄ Hdj-1 in suppressing polyQ aggregation [15] Nevertheless, Hsp27 protects neuronal cells against apoptosis [41,42], oxidative stress ... together, these results also suggest that proteasome partial inhibition by httEx1-polyQ is not the major cause of the oxidative stress observed in cells expressing these proteins 20 20 Discussion ... through its antioxidant-related properties [15] Hsp overexpression in COS-7 cells was assessed by transient transfection using vectors encoding either Hsp70, Hdj1, Hdj-2 or Hsp27 Hdj-2 is an isoform...

Ngày tải lên: 19/02/2014, 06:20

... countries with larger stockpiles Candidate groups include close contacts of cases (especially those who are at high risk of developing severe disease), family contacts and key workers for business ... optimise the usefulness of existing stockpiles small or large An important general principle contends that having stockpiles is of limited use without agreed objectives, protocols, administration ... to reflect those most at risk with the pandemic strain All people just starting an illness Within 48 hours of the first symptoms Prophylaxis: The use of antivirals for prophylaxis can be considered...

Ngày tải lên: 05/03/2014, 22:21