which patients with pn are more likely to fall
Báo cáo y học: " FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease" pdf
... lead genes For a cutoff from to with an increment of 0.02, differentially expressed genes with DER values greater than the cutoff were compared with the list of disease genes to calculate the precision ... erythemetosus (SLE) is an autoimmune disease with multiple organ involvement and a genetic predisposition Renal disease occurs in 40% to 75% of SLE patients and up to 90% of childhood SLE patients, ... for the top seven loci Genes with DER value ≥ 0.55 and -log10P >5 were predicted to be T1DM genes, and compared with the validation findings Mapping diseases without known molecular basis to lead...
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Báo cáo y học: " CD4 count at presentation for HIV care in the United States and Canada: Are those over 50 years more likely to have a delayed presentation" pps
... or within three months prior to, first presentation for HIV care compared to younger individuals The increase in the proportion of individuals who were ≥50 years at first presentation for care ... presentation for HIV care in the United States and Canada: Are those over 50 years more likely to have a delayed presentation? AIDS Research and Therapy 2010 7:45 Submit your next manuscript to BioMed Central ... compared to the
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Báo cáo y học: " Which patients with rheumatoid arthritis are still working" pps
... personal factors Some of these factors are modifiable, others are not Page of We still need to learn more about which factors are facilitators and barriers for work ability in RA patients, but ... risk factor for permanent work disability, and biological drugs are not necessarily initiated when patients are most vulnerable to losing their work With all the due caveats applicable to this ... with a higher gross domestic product (GDP) or those with a lower GDP Generally, better clinical status was seen in those patients still working, but a striking finding was that patients who stopped...
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báo cáo hóa học:" Primary cultured fibroblasts derived from patients with chronic wounds: a methodology to produce human cell lines and test putative growth factor therapy such as GMCSF" ppt
... from wounds in patients with diabetes have been evaluated for mitogenic response with a variety of growth factors [23,26] and show a lower rate of proliferation when compared with normal skin ... from the debrided tissue samples from patients with chronic wounds Fifteen biopsies were sent to Coriell along with de-identified patients' medical history, history of diabetes, age, sex, ethnicity, ... marker are provided in Table The alleles of all cell lines were determined by sizing on the Applied Biosystems 3730, downloaded to the Repository database, and compared to those already recorded to...
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báo cáo hóa học:" Improvement in quality of life measures in patients with refractory hepatitis C, responding to re-treatment with Pegylated interferon alpha -2b and ribavirin" docx
... better HRQOL scores (compared to prior non-responders) as the majority of those who responded were prior relapsers Also, those with better HRQOL may be more likely to tolerate the treatment better ... in responders among refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin SF-36 domain Change in QOL scores compared to baseline At 48 wks to 24 wks (24 wk48 wk) 24 ... non-responders among refractory HCV patients re-treated with pegylated interferon alpha 2b and ribavirin SF-36 domain Change in scores compared to baseline at 48 wks to 24 wks (24 wk48 wk) 24...
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Báo cáo y học: "Raised intrathecal levels of APRIL and BAFF in patients with systemic lupus erythematosus: relationship to neuropsychiatric symptoms" docx
... in NPSLE patients compared with systemic lupus erythematosus patients without central nervous system symptoms Separate analyses of APRIL levels in SLE patients with NPSLE and patients without ... systemic lupus erythematosus patients It has been reported that the inflammatory cytokine IL-6 is raised in the CSF of NPSLE patients compared with SLE patients without CNS symptoms [40], and this ... detected between SLE patients Figure Raised APRIL levels in NPSLE patients compared with SLE patients without central nervous system symptoms Cerebrospinal fluid (CSF) levels of symptoms (a) APRIL...
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Báo cáo y học: "Airflow limitation or static hyperinflation: which is more closely related to dyspnea with activities of daily living in patients with COPD?" ppt
... suggested to be a better measurement than peak dyspnea during exercise Furthermore, the inspiratory capacity (IC) has been shown to be more closely related to exercise tolerance and dyspnea than ... Respiratory Medicine, Rakuwakai Otowa Hospital, Kyoto, Japan; Kyoto-Katsura Hospital, Kyoto, Japan; and Department of Respiratory Care and Sleep Control Medicine, Graduate School of Medicine, Kyoto ... static hyperinflation: which is more closely related to dyspnea with activities of daily living in patients with COPD? Koichi Nishimura1, Maya Yasui2 , Takashi Nishimura2 , Toru Oga3 AFFILIATIONS:...
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Báo cáo khoa học: " Randomized controlled trials are needed to determine appropriate blood transfusion strategies in patients with acute coronary syndromes" pdf
... transfusion to maintain arbitrary hematocrit levels in stable patients with ischemic heart disease PARAGON [9]) They found that transfusion was associated with an increased hazard for death within ... restrictive strategy generally appears to be safe in most critically ill patients with cardiovascular disease, with the possible exception of patients with acute myocardial infarction and unstable ... results can be applied to patients with cardiac disease who not meet GUSTO IIb, PURSUIT, or PARAGON entry criteria, such as those with cardiovascular disease coincident to critical illness Recommendation...
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Báo cáo y học: "Acute and delayed mild coagulopathy are related to outcome in patients with isolated traumatic brain injury" docx
... alcohol intoxication is a common finding in patients with isolated TBI and suggested that alcohol intoxication is associated with a lower incidence of coagulopathy as compared to non-intoxicated patients ... 1.00 liter vs 0.53 ± 0.55 liter; P = 0.01) as compared to patients without early hemostatic disorders Moreover, patients without coagulopathy more frequently used alcohol before the traumatic ... laboratory values upon ED admission of patients with and without coagulopathy Patients with coagulopathy had lower hemoglobin levels, platelet counts, and an increased PT and aPTT in comparison with...
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Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"
... reported to affect the quality of life which in turn can be improved after treatment [13,14] Symptoms in HCV infection not appear to be linked to disease activity; neither appear to be correlated with ... are several high-risk groups for HCV infection Individuals with a history of transfusion of clotting factors prior to 1987, as well as blood products or received organ transplantation prior to ... prior to 1992 should be tested Patients with a recent or remote history of injection drug use, on chronic hemodialysis, infants born to mothers with HCV or those with evidence of unexplained liver...
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Báo cáo khoa học: LmbE proteins from Bacillus cereus are de-N-acetylases with broad substrate specificity and are highly similar to proteins in Bacillus anthracis pot
... and acetate atoms were removed Hydrogen atoms were added to the crystal structure, and the substrates and atomic partial charges were assigned to the protein and carbohydrate atoms Atomic interaction ... enzymes are the products of convergent evolution due to similar active site features The objective of this study was to shed light on the role of two de-N-acetylases from B cereus, which are LmbE ... interactions with residues that occupy positions 140 and 42 are indicated (C) Position 140 The native Arg residue (carbon atoms in yellow) and the mutations Ala (carbon atoms in brown) and Glu (carbon atoms...
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Patients With Pulmonary Tuberculosis Are Frequently Positive for Anti–Cyclic Citrullinated Peptide Antibodies, but Their Sera Also React With Unmodified Arginine-Containing Peptide potx
... peptide (CAP) was examined in patients with TB and compared with that in patients with RA PATIENTS AND METHODS Patients Sera were obtained from Japanese patients with pulmonary TB (n ϭ 49) or ... CCP or CAP to cross-inhibit the reactivity of sera from patients with TB compared with sera from patients with RA (Figure 2D) may be due to the presence of low-avidity antibodies or to the differences ... peptide (anti-CCP) antibodies compared with anti–unmodified arginine-containing peptide (anti-CAP) antibodies in patients with rheumatoid arthritis (RA), patients with tuberculosis (TB), and in...
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Are Bonds Going to Outperform Stocks Over the Long Run? Not Likely. pptx
... or related to, the information, data, analyses or opinions or their use July 2009 Page Stocks vs Bonds in the Future How likely are stocks to outperform bonds going forward? To try to figure ... least as likely to rise as to fall3 If there were no future fall in yields, all of the return would have to come from the coupon return That means the total returns for bond investments would likely ... is very unlikely to repeat in the future, given today’s low interest rate environment Investors hoping bonds will outperform in the coming years will likely be disappointed Stocks tend to outperform...
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Báo cáo hóa học: " Mutation or loss of Wilms’ tumor gene 1 (WT1) are not major reasons for immune escape in patients with AML receiving WT1 peptide vaccination" ppt
... To correct for differences of cDNA amount on a per-sample basis, results were provided as ratio to PBGD expression Page of Mutation analysis Base exchanges within the epitope sequence or epitope ... and for mutations of the WT1 epitope or epitope flanking sequences All patients had received sequential vaccinations with the HLA-A2-restricted WT1 126-134 peptide with adjuvants Busse et al Journal ... in patients To exclude failure of vaccine efficacy due to HLA class I downregulation [16-18,25], cell surface HLA class I expression on leukemic blasts was analyzed in patients by flow cytometry...
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Báo cáo hóa học: " Incidence of the V600K mutation among melanoma patients with BRAF mutations, and potential therapeutic response to the specific BRAF inhibitor PLX4032" potx
... melanoma patients appears to be higher than is commonly assumed It can be present in up to 30% of patients bearing BRAF V600 mutations, potentially representing up to 10% of all melanoma patients Patients ... V600K and V600E mutations, together with clear evidence of clinical activity of PLX4032 in a patient with a documented V600K mutation, suggest that melanoma patients with V600K mutations should ... treatment to the specific genetic composition of the tumor [5] One of our patients with locally advanced unresectable melanoma involving the skin of the left chest wall, progressing after treatment with...
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Báo cáo hóa học: " Abstract Despite new additions to the standard of care therapy for high grade primary malignant brain tumors, the prognosis for patients with this disease is still poor." ppt
... radio-chemo-therapy In one arm of the trial patients also receive the anti-IL-2Ra (daclizumab), since Treg cells are more sensitive to that antibody compared to the cytotoxic T cell counterpart Intradermal ... (NCT00905060) patients with GBM Enrolled patients are being vaccinated with the heat shock protein peptide complex (HSPPC)-96 with or without concurrent TMZ therapy Heat shock proteins (HSP) are highly ... strategies in patients with recurrent grade III or IV glioma (NCT01081223) Patients are immunized with irradiated autologous tumor cells and GM-CSF (TVAX) Later, autologous T cells are harvested...
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báo cáo sinh học:" Training health care workers to promote HIV services for patients with tuberculosis in the Democratic Republic of Congo" pptx
... http://www.human-resources-health.com/content/7/1/23 thermore, HCWs in the capital are more likely to have been exposed to HIV and TB messages and training compared to nurses employed in more rural areas Knowledge of HCWs in ... HIV care and support for HCWs involved in the care of patients with TB at the primary health care clinic level in the DRC Methods Identification of target health care workers Primary health care ... Activities to reduce the burden of HIV among TB patients and activities to reduce the burden of TB among people living with HIV/ AIDS are therefore urgently needed [3] HIV counseling and testing of patients...
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báo cáo hóa học: " The AMC Linear Disability Score (ALDS): a cross-sectional study with a new generic instrument to measure disability applied to patients with peripheral arterial disease" potx
... outcome scales [20] have been examined in depth patients with CLI, with ALDS scores to be expected higher in patients with IC than in patients with CLI From the ALDS itembank, two questionnaires ... rest (in patients with CLI) Decrease ABI after exercise (in patients with IC)a 0.35 (0-0.59) 0.28 (0.09-0.55) Toe pressure mmHg (in patients with CLI) 19 (0-67) ALDS 71 (± 17) VascuQol total 3.7 ... patients with claudication (ALDS score 80) than in patients with CLI (ALDS score 64) Similar results were obtained for the VascuQol total score (4.5 in patients with claudication and 3.1 in patients...
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Báo cáo sinh học: "Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh-HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety" ppt
... enrolled into the study Selection of patients Consenting patients were prospectively screened from September 2005 to June 2008 Eligible patients with FHSA or LOHF, who were not able to receive ... Miyazaki H, Sugihara J, Tomita E, Muro Y, Daikuhara Y, Hashimoto S: Clinical significance of human hepatocyte growth factor in blood from patients with fulminant hepatic failure Hepatology 1989, 9:875-881 ... growth factor (HGF) was first purified as a potent mitogen for hepatocytes from the plasma of patients with FH [8,9] HGF is one of the primary agents promoting the proliferation of mature hepatocytes...
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