... polymorphism was associated with an increased risk of coronary heart disease [9,22] whereas others failed to demonstrate this association [23-25]. Furthermore, a recent meta-analysis study ... Medical Sciences ISSN 1449-1907 www.medsci.org 2004 1(3):181-192 â2004 Ivyspring International Publisher. All rights reserved Elevated plasma homocysteine is positively associated with age independent ... Coagul Fibrinolysis. 2002;13(3):271-5. 53. Klerk M, Verhoef P, Clarke R, Blom HJ, Kok FJ, Schouten EG. MTHFR 677C >T polymorphism and risk of coronary heart disease: a meta-analysis. JAMA. 2002;288(16):2023-31....
Ngày tải lên: 03/11/2012, 09:49
... chronic gastritis and ulcer (normal group), 50 with IM including adenoma (high risk group), 40 with EGC (EGC group), 45 with AGC with- out distant metastasis (AGC group), and 42 with meta- static ... gastric carcinogenesis. Serum HMGB1 levels were significantly associated with depth of invasion, lymph node metastasis, tumor size, and poor prognosis (p < 0.05). However, HMGB1 levels were not associated with ... meas- urement of HMGB1 activity in tissues is clinically impor- tant, this method of biomarker analysis is somewhat limited because the measurement of biomarker activity in tissue requires invasive techniques...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: " Mild hypoglycemia is strongly associated with increased intensive care unit length of stay" pdf
... Multivariate analysis of factors associated with ICU LOS Table 2 demonstrates that hypoglycemia—minimum BG < 50 mg/dL as well as minimum BG 50–69 mg/dL is independently associated with prolonged ... of the patients with hypoglycemia in the NL cohort had an episode within the first 48 hours of ICU admission. Figure 5 displays the strong association between the number of episodes of hypoglycemia ... associated with mortality on univariate analysis and therefore was not entered into the multivariate model. Mortality is defined throughout as hospital, not ICU, mortality. Statistical analysis was...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo y học: "Is Obesity Associated with an Increased Risk for Airway Hyperresponsiveness and Development of Asthma" pdf
... variable in logistic regression models, one unit of increased BMI (1 kg/m 2 ) was associated with a 3.1% increase in AHR risk (CI 1.01–1.05; p , .005) in all subjects. For men, this risk was 3.4% ... a 25 kg weight gain was associated with a 2.5-fold increase in the risk for diagnosis of asthma compared with no significant weight gain. 11 In a cross-sectional analysis of 18,000 children aged ... the two. Our study estab- lished obesity as a risk factor for new diagnosis of asthma, the risk increasing with higher levels of obesity. These findings should be the basis for future controlled investigations...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population" pdf
... medialis at the patellofemoral joint is also supported by electromyography studies, which demonstrated that delayed activation of vastus medialis relative to vastus lat- eralis is associated with ... results in a pain-free population without clinical knee oste- oarthritis suggest that increased cross-sectional area of vas- tus medialis, which is associated with participation in vigorous physical ... study is unknown. Thus, the aim of this study was to examine the determinants of vastus medialis and lateralis cross-sectional areas and whether vastus media- lis cross-sectional area is associated...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis" potx
... Research Divisions. We also thank Dr Olle Olerup for providing us with HLA typing kits, Miss Diab Diab for technical assistance with HLA typ- ing, and Mr Ben de Jong for technical assistance with serum ... Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's ... study and is respon- sible for the Blood Bank in Umeå. HS assisted in the statistical analyses and discussions. Acknowledgements We gratefully acknowledge the technical assistance of Mrs Lisbeth...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx
... univariate analysis (P > 0.05) and Cox's multivariate analysis. Table 1: Distribution of 50 patients with cutaneous melanoma in terms of primary diagnosis and location of tumor and first metastasis Primary ... mechanism through which bcl-2 inhibits apoptosis is not fully understood [19]. In the presence of bcl-2 overexpression, the ability of the cell to remove genetic and cell damage through apoptosis is ... metastases and one for disease in the axilla, all with palliative intent. Immunohistochemistry Sections of paraffin-embedded metastasis specimens were initially stained with hematoxylin-eosin...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: "The MHC2TA -168AG gene polymorphism is not associated with rheumatoid arthritis in Austrian patients" pps
... -168A>G polymorphism has convinc- ingly been associated with MHC2TA gene expression, it is unclear whether the polymorphism itself is functional or whether it is in linkage disequilibrium with one or ... Revisions requested: 6 Apr 2006 Revisions received: 8 May 2006 Accepted: 17 May 2006 Published: 15 Jun 2006 Arthritis Research & Therapy 2006, 8:R97 (doi:10.1186/ar1974) This article is online ... purposes) Vol 8 No 4 Research article The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients Babak Yazdani-Biuki 1 , Kerstin Brickmann 1 , Klaus...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... Comparison of risk factors for vascular disease in the carotid artery and aorta in women with systemic lupus erythematosus. Arthritis Rheum 2004, 50:151-159. 35. Vitali C, Bencivelli W, Isenberg ... analysis. As a consequence of the low number of opportunistic infec- tions since lupus onset in our patients, a further analysis of var- iables associated with the occurrence of opportunistic infections ... in other studies in patients with SLE [1,30] is confirmed by our study, which shows a third of the infections in patients with SLE to be major infections for which hospital admission was required. Furthermore,...
Ngày tải lên: 09/08/2014, 08:23
Báo cáo y học: "The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis" pptx
... Revisions requested: 27 Feb 2007 Revisions received: 16 Apr 2007 Accepted: 18 Apr 2007 Published: 18 Apr 2007 Arthritis Research & Therapy 2007, 9:R40 (doi:10.1186/ar2179) This article is ... because IFIH1 is a highly IFNβ- inducible protein that is thought important in mediating IFNβ effects such as growth inhibition and apoptosis [23]. Immuno- histochemical analysis has shown IFNβ ... distribution. All gene expression analysis was performed using GraphPad Prism Version 4 (GraphPad Software, San Diego, CA, USA). Results IFIH1 A946T is not associated with RA susceptibility or severity Allele...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Leg-length inequality is not associated with greater trochanteric pain syndrome" pps
... LLI. The most probable explanation for this finding is that, despite opinion found in textbooks, no association actually exists. This reasoning is consistent with the near absence of data support- ing ... 11 cases with ipsilateral longer leg, and 17 cases with bilateral GTPS) and in 163 subjects without GTPS; therefore, 13.7% of subjects with GTPS had a LLI compared with 14.1% of those without ... 2007 Revisions received: 12 Apr 2008 Accepted: 29 May 2008 Published: 29 May 2008 Arthritis Research & Therapy 2008, 10:R62 (doi:10.1186/ar2433) This article is online at: http://arthritis-research.com/content/10/3/R62 â...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Vastus medialis cross-sectional area is positively associated with patella cartilage and bone volumes in a pain-free community-based population" ppt
... medialis at the patellofemoral joint is also supported by electromyography studies, which demonstrated that delayed activation of vastus medialis relative to vastus lat- eralis is associated with ... in multivariate analysis. BMI was positively associated with vas- tus medialis cross-sectional area in multivariate analysis, with a similar trend observed with vastus lateralis. Participation in vigorous ... results in a pain-free population without clinical knee oste- oarthritis suggest that increased cross-sectional area of vas- tus medialis, which is associated with participation in vigorous physical...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: "Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome" potx
... deviations) in cases of normal distribution or as medians (interquartile ranges) in cases of non- normal distribution. BMI, body mass index; CRP, C-reactive protein; DAS28, disease activity score using ... DMARD, disease- modifying antirheumatic drug; ESR, erythrocyte sedimentation rate; HCQ, hydroxychloroquine; MTX, methotrexate; RA, rheumatoid arthritis; SSZ, sulfasalazine; TNF, tumour necrosis factor. Table ... only, hydroxychloroquine only, tumour necrosis factor-blocking agents, combination of disease-modifying antirheumatic drugs, pack-years, smoking, erosions, DAS28 (disease activity score using 28 joint...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome – authors’ respons" pps
... competing interests. Acknowledgements This work is supported by an Arthritis Research Campaign Clinical Fel- lowship grant (grant number 18848 to TET) and an Arthritis Research Campaign infrastructure ... Foundation Trust, Department of Rheumatology). HJ is supported by an Arthritis Research Campaign Educational Research Fellowship Grant (grant number 17883). VFP is supported by a PhD scholarship from the ... associates with a reduced prevalence of the meta- bolic syndrome in rheumatoid arthritis patients over the age of 60: more than just an anti-inflammatory effect? A cross- sectional study. Arthritis Res...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage" potx
... quasispecies variants was 15%. In this cohort, only patients with major L76V positive population were included. Minor wildtype variants were not detected at this position. Phenotypic resistance ... 3.6 HIVGrade Phenotype Resistant Intermediate Sensitive Resistant Intermediate Sensitive Figure 1 Resensitizing effects of the L76V mutation are visible in phenotype results: Phenotypic resistance analysis before ... therapy was noticeable associated with an additional establishment of t he protease gene muta- tion at position L90 M which resulted in resistance against all available PIs [17]. Six of eight patients...
Ngày tải lên: 10/08/2014, 05:22
báo cáo khoa học: "Overexpression of LCMR1 is significantly associated with clinical stage in human NSCLC" ppt
Ngày tải lên: 10/08/2014, 10:21
Báo cáo khoa hoc:" Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis" ppt
Ngày tải lên: 11/08/2014, 07:21