what role did geography play in the rise of greek citystates
Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... awell-defined hyperintensity mass in the cervical area. The shape of the uterine cervix is distorted in the DWI (arrowhead). d On the ADC map the tumor is hypointense (arrow) and the normal ... imaging technique (SENSE factor of 2). Imaging time of DWI was 90 s for 20 slices.Detection of uterine malignancy The ADC values of uterine cancers are lower than of normal tissue. On the other ... with uterine leiomyomas and ableeding cyst. a Axial T2-WI shows an area of hypointensity in the center of the cystic component (arrow). b On T1-WI with fatsuppression the area in the cystic...
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Tài liệu Affluent In The Face Of Poverty - On What Rich Individuals Like Us Should Do docx
... Theory of the Good 149 6.1.1 Some Rather Formal Remarks on the Good 149 6.1.2 A Theory of the Good in Broad Outline 154 6.1.3 The Outline and What We Should Do 165 6.1.4 The Outline, the ... happenings, and then simply directs agents to do what is in their power to produce those states of affairs or sets of happenings.20 In the light of the above remarks, the striking thing about ... welcome thee, or naked and clothe thee? And when did we see thee sick or in prison and visit thee?’ And the King will answer them, ‘Truly, I say to you, as you did it to one of the least of these...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... functional mapping of the cyclinB1 promoter did not yield the class II CHR as the sitethrough which Lin-9 exerts its control [94]. In anotherreport, depletion of Lin-9, Lin-37, Lin-52 or Lin-54 byRNAi ... Dimethyl sulfate footprint-ing of the CDE in the presence of SV40 large T indi-cated a loss of protein occupation on this site in vivo[79].Elevated expression of cyclin A, cyclin B, Cdc25Cand Cdc2 ... appearsstronger in G2⁄ M than in G1[44]. This contradictsrepression through a complex in G1and in vivo foot-printing results in the original definition of the sites[10]. Taken together, the sites in...
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Tài liệu Báo cáo khoa học: Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen pdf
... TGF-aD152 (lacking the lasteight amino acids of the ICD) compared to the TGF-aD158 construct lacking only the last two valine resi-dues, suggesting a role for an internal motif in the interaction ... identified the EWV614motif in MT5-MMP ICD as comprising animportant sequence for the interaction with the PDZproteins: Mint-3, AMPA binding protein and gluta-mate receptor interacting protein (GRIP). ... lane 4), therefore confirming the interaction of these two proteins previously observed biochemically[37] or using a yeast two-hybrid assay [39]. Interestingly, in the M2H system, the interaction...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati,OH, USA) constantly maintained at 1% O2. Culturemedium ... lgÆmL)1insulin, 1 lm dexamethasone, and0.5 mm IDM). Cells were then maintained in DMEM con-taining 10% fetal bovine serum and 1 lgÆmL)1insulin. The medium was replaced every other day. ... cultured in DMEM containing 10% fetal bovineserum. OP9 cells were grown in aMEM containing 20%fetal bovine serum. C2C12 cells were maintained in DMEMcontaining 10% fetal bovine serum.Adipogenic...
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Tài liệu Báo cáo khoa học: High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation docx
... folding of the mutant. The lowerintensity may arise from partitioning of the proteininto an aggregated state. The effect of copper binding on the secondary struc-ture was determined using CD in ... important in the brain, there-fore the role of copper binding or loss of its bindingcould be related to specific cerebellar function(s) of stefin B [18], which remains to be seen by more in vivostudies.Stefin ... human cystatins.Further support for the premise that the C-terminuscould be the copper binding domain comes from stud-ies of the P79S mutant, which differs from the copperbinding forms of stefin...
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Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx
... undergoes fusion with the membrane of intra-endosomal vesicles contained within MVBs,thereby releasing the nucleocapsid into the lumen of these vesi-cles. Then, the capsid uses these intra-endosomal ... milddevelopmental delay. The protein defective in this disorder is alsoa NHEJ protein. The distinct clinical features of the patients willbe discussed in the context of the protein function.3.4 Diabetes, ... bedue to increased protein damage and/or decreased elimination of oxidized protein. Since the proteasome is in charge of protein turn-over and removal of oxidized protein, its fate during ageing...
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Tài liệu The Rise of Political Economy in the Scottish Enlightenment docx
... gainsindependence from the king and his court, and plays a role as a balance against the king’s power. Furthermore, instead of betraying the interest of their countryto the court in the metropolis (London) ... the vital importance of the role of the gentry in the development of the Scottish economy as the vital link in the circular flow of the economic system. Thus he wished that the gentry would keep ... western parts of the Roman empire introduced the following form of government into all the nations they subdued. The general of the army became king of the conquered country, and he divided the landsamong...
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Tài liệu Báo cáo khoa học: The role of the ESSS protein in the assembly of a functional and stable mammalian mitochondrial complex I (NADH-ubiquinone oxidoreductase) pptx
... proposed X-linkage.Sequence analyses of the ESSS cDNA in these mutantsrevealed chain termination mutations. In two of thesemutants the protein i s truncated at the C-terminus of the targeting sequence; ... likely that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspeciesinteractions are incompatible.From ... and the effect of the absence of intact complex I, but the results are toopreliminary in this regard.Heterologous expression of the ESSS-HA subunit The localization of the ESSS subunit in the...
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Tài liệu Báo cáo khoa học: A role for the intersubunit disulfides of seminal RNase in the mechanism of its antitumor action docx
... thusblocking protein synthesis and leading cells to death. The current model proposed for the mechanism of antitumouraction of BS-RNase is based on the ability of the proteinto resist the neutralizing ... plateau.These data indicate that the cell sulfhydryls responsiblefor the exchange with the protein disulfides are located in the plasma membrane. Furthermore, they show that, asproposed in the hypothesis ... hypothesize that the cytotoxicactivity of the latter monomers was due to the presence in these proteins of disulfide bonds, with their potentialchemical instability. It is well known that in the...
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Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... demonstrates the important role of GALA in the degradation of both linear andL-arabinose-substitutedgalactan side chains of pectin. This is in agreement with aprevious study in which the synergy of ... under the control of the xylanolytic activator protein [32,41]. The increase in expression levels of galA in the CREA mutant,indicates that at least one of the detected putative CREAbinding sites ... synergy of enzymes degrading the pectin side chains was studied [34]. GALA had a positiveeffect on the activity of the other enzymes involved in the degradation of these side chains.DISCUSSIONA....
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Role of Corticosteroids in the Treatment of Tuberculosis: An Evidence-based Update potx
... imaging of the brain was also performed in a subset of patients in this study.36 It was found that use of corticosteroidspossibly reduced the risk of developinghydrocephalus and vasculitic infarcts; ... of opportunistic infections in HIV-infected adults andadolescents: recommendations from CDC, the NationalInstitutes of Health, and the HIV Medicine Association of the Infectious Diseases Society of America. ... Vietnam. Following the publication of this trial, Prasad and Singh12 updatedtheir Cochrane systematic review on the efficacy of corticosteroids in TBM.12 The combined mortality in the control...
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ROUTLEDGE STUDIES IN SCIENCE, TECHNOLOGY AND SOCIETY: Human-animal relations and the rise of veterinary medicine pot
... scavenging, hunting and gathering in favour of animal husbandry and agriculture. In this chapter, I have chosen tooutline some of the most influential and interesting of these theories. By producing ... underlay the introduction of publicslaughterhouses in the Netherlands and the increasingly important role of veterinary meatinspection; and finally, Schwabe (1978) examines early animal medicine ... as they were exploited with due care and respect. Further to this change in theological thinking, from the mid-eighteenth century onwards, there was increasinginterest in the welfare of the...
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Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx
... which was indeed predicted. The other maingroup, obtained 97% of the time in 20 740 exploredtrees, contained the DIDO PHD sequences clusteredwith the PHF and the CGBP proteins. As seen in the tree, ... little is known about their role in DIDOactivity. The combination of domains (domain shuffling)is a driving force in Eukarya in the acquisition of KeywordsCGBP; DATF1; DIDO1; DIO; SPP1CorrespondenceA. ... modifications of chromatin [9]. Little isknown, however, of the functional role of the remain-ing subclass members. In this study, the yeast protein SPP1 (alias cps40), amember of the COMPASS...
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Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf
... of GSK3 (using Li or SB-415286)appears to be sufficient for inducing activation of GS in muscle and fat cells, and that inhibition of the kinasepotentiates insulin action in muscle of insulin-resistant ... (1994) The inhibition of glycogensynthase kinase-3 by insulin or IGF-1 in the rat skeletal muscle cellline L6 by wortmannin, but not rapamycin: evidence that wort-mannin blocks activation of the ... phosphatidylinositol3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammaliantarget of rapamycin (mTOR) pathway in the L-leucine-inducedup-regulation...
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- the rise of greek
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