what is legally required in a contract of employment

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... image is the same features, normal or anomalous, in opposite organs in MZ, which is esti- mated to occur in 25% of MZ 12 . It is a characteristic feature of MZ. The mechanism of mirror imaging ... trauma, infection, intrauterine catastrophes 16 or head surgery 17 . In our case, the lack of a previous history of trauma, infection and head surgery leads us to believe that the AC was ... Microar- ray-based gene expression profiling and DNA copy number variation analysis of temporal fossa arachnoid cysts. Cerebro- spinal Fluid Research. 2010; 7: 6-13. 20. Helland CA, Aarhus M, Knappskog...

Ngày tải lên: 25/10/2012, 11:00

... tourists and organizations. In the words of Barbara Czarniawska, today’s organizations are faced with the frantic production of images which are circulated; a frantic translation of incoming images ... longer is associated with goods consumed, but that the accumulation and proliferation of cultural capital is more becoming a matter of practice: eating at particular restaurants, staying at particular ... reducing our use of material and nonrenewable energy and a myriad of tools and concepts embracing presented as tools for achieving sustainability (including initiatives such as LCA, dematerialization,...

Ngày tải lên: 19/02/2014, 17:20

... knowledge and skills of psychodynamic and emotional management into the ongoing challenges and tasks of leading, managing, and changing organizational systems greatly adds to the likelihood that any ... managers and staff interacted. They wanted an organiza- tion that valued people, encouraged innovation and creativity, and rewarded leadership and risk taking, outcomes that any management or ... vast diversity in the variables that affect human organizational life, it is easy to see the impossibility of the average consultant or coach understanding everything that is hap- pening in...

Ngày tải lên: 21/02/2014, 16:20

Ngày tải lên: 21/02/2014, 20:20

... envelhecimento, memória, cognição, testes neuropsicológicos. Behavioral and Cognitive Neurology Unit, Department of Internal Medicine, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte,  Brazil. Paulo Caramelli  –  Department of Internal Medicine / Faculty of Medicine / Federal University of Minas Gerais - Avenida Prof. Alfredo Balena, 190 /  Room 246 - 30130-100 Belo Horizonte MG - Brazil. E-mail: caramelp@usp.br Received 01/30/2008. Received in final form 02/19/2008. Accepted 02/19/2008. 44 ... 2008;2(1):42-45 Memory loss is one of the most common complaints  arising in consultations with elderly people, being reported  by 25% to 50% of these individuals. 1  However, whether  these subjective memory complaints (SMC) are related to  objective memory deficits or to subsequent development  of dementia, remains a matter of debate. A recent review found that SMCs are not consistently  associated with current cognitive impairment, but rather  are associated with a greater risk of future cognitive de- cline. 2  Indeed, the diagnosis of mild cognitive impairment  (MCI), which entails an increased likelihood of conversion  to dementia, demands the existence of SMCs, preferably  confirmed by an informant. 3 High age, female gender and low educational level are  generally associated with a higher prevalence of memory  complaints. 1 In an autopsy study, SMCs were found to be  related to the presence of Alzheimer’s disease (AD) pathol- ogy in elderly with and without dementia, suggesting that  memory complaints in older persons may be a sign of self  awareness of a degenerative process. 4 However, SMCs might also be related to depression and  some personality traits, such as neuroticism. 2  It is also pos- sible that these complaints vary according to the culture of the people studied. In a recent Brazilian study, Minett et  al. found that subjects with and without SMCs performed  similarly in a series of cognitive tests, although the former  had higher scores on the Geriatric Depression Scale. 5 The present study aimed to further investigate this topic  in a group of cognitively healthy Brazilian elderly subjects  which were divided into two subgroups according to the  presence of SMCs and submitted to brief cognitive tests. Methods Sixty cognitively intact elderly individuals (39 females  and 21 males), aged 69.9±6.3 years (ranging from 60 to 91  years), and with mean educational level of 8.5±5.5 years  (ranging from 1 to 20 years), were included in the study.  These individuals were family caregivers of demented pa- tients followed at the Behavioral and Cognitive Neurology  Unit of the Faculty of Medicine of the Federal University  of Minas Gerais, in Belo Horizonte (MG), Brazil, and also  volunteers recruited from the community. Inclusion criteria were absence of neurological or psy- chiatric diseases according to a clinical interview, absence  of depression (see below), and no use of benzodiazepines,  antidepressants or neuroleptics.  All participants were submitted to the Mini-Mental  State-Examination (MMSE) 6,7  and to the Cornell scale of depression. 8,9  Performance on the MMSE was adjusted for  educational level and had to be greater than or equal to 21  for 1-3 years of schooling, greater than or equal to 24 for  4-7 years and greater than or equal to 26 for individuals  with 8 or more years of schooling. 10  Scores on the Cornell  scale of depression had to be less than or equal to 7 points  in order to rule out depression. 8 Cognitive evaluation was carried out with the follow- ing tests: the Brief Cognitive Screening Battery (BCSB) 11,12 ,  digit span forward and backward and the Frontal Assess- ment Battery (FAB). 13,14  The BCSB includes a memory test  of 10 simple figures and yields different scores, namely:  incidental and immediate memory, learning, delayed recall  and recognition. 15,16  The battery also includes a category  fluency test (animals per minute) and clock drawing and  has proven very sensitive in the diagnosis of mild AD. 12  The  FAB is a brief diagnostic instrument for the assessment of executive functions in patients with suspected frontal lobe  syndrome. 13 All individuals were given a structured self-report  memory questionnaire, the MAC-Q. 17  This questionnaire  was devised to assess age-related memory decline. It is composed by six questions related to memory function- ing in everyday situations (e.g., to remember a telephone  number that he/she uses at least once a week) in which  the subject is asked to compare and rate his/her current  ability to when he/she was 40 years’ old. The total score on  the MAC-Q ranges from 7 to 35, where greater scores in- dicate subjective memory loss. Scores greater than or equal  to 25 have been found to be suggestive of age-associated  memory impairment. Accordingly, in the present study,  the individuals were divided into two groups: absence of SMCs (MAC-Q scores <25) and presence of SMCs (MAC- Q scores ≥25). The performance of the two groups on the  different cognitive tests was compared. One of the authors administered the MMSE, the Cor- nell scale and the MAC-Q. Subsequently, the other inves- tigator, blinded to the subjects’ results for these three mea- sures, administered the cognitive evaluation. Descriptive analysis of the data and statistical compari- sons between the performances of the two groups on the  different cognitive tests were carried out with MedCalc  software. Student’s t-test was used for comparison of age,  educational level and MMSE scores, as well as for the results  of the other cognitive tests (digit span, BCSB and FAB).  Chi-square was employed for comparing gender distribu- tion of the two groups. Level of significance was set at 0.05.  The study was approved by the Research Ethics ... 2008;2(1):42-45 14 women and 13 men, aged 69.6±5.4 years, with mean  educational level of 8.8 years. Mean MMSE score of this  group was 27.8. The group of complainers (MAC-Q scores ≥25) was  composed by 25 women and 8 men, aged 70.3±7.0 years,  with mean educational level of 8.2 years. Mean MMSE  score of this group was 27.2. No significant difference for age, gender, education and  MMSE scores were found between the two groups. Table 1  depicts the main demographic data as well as the MMSE  and MAC-Q values for both groups.  The comparison between the performance of the  groups of complainers and non-complainers on the dif- ferent cognitive tests yielded no significant difference, al- though there was a trend for non-complainers to perform  better in incidental memory. Table 2 presents the scores from the two groups in all  tests as well as the statistical comparisons between them. Discussion In the present study, we found no significant difference  in the performance of elderly subjects with and without  SMCs on a series of brief cognitive tests assessing attention,  episodic and semantic memory, and executive functions.  Only a trend toward a significant difference emerged for  the subtest of incidental memory from the BCSB, an item  that is more related to attention than to memory itself. Some previous studies have found a relationship be- tween SMCs and objective memory performance, while  many others have not. 2  The methodology adopted by the  different studies in assessing SMC varies, where some use  only a simple question about perceived memory problems,  while others base this classification on the results of specific  questionnaires, such as the MAC-Q used in our study.  Interestingly, a previous Brazilian study compared the  use of the MAC-Q with direct questioning about memory  problems, and found that a significant percentage of the  sample had SMCs, based on the response to the direct ques- tion along with low scores on MAC-Q, while other subjects  had no SMCs and high MAC-Q scores. 18  Performance on  a memory test did not differ according to the MAC-Q re- sults, mirroring our findings, although was worse in those  individuals presenting SMCs upon direct questioning. High age, female gender and low education have all  been associated with an increased prevalence of SMCs.  Our sample is composed exclusively by elderly subjects  (≥60 years), with a predominance of women (39 vs. 21)  and with low to middle educational level, especially com- paring with studies conducted in North America, Europe  or Japan. These features might explain the high percentage  (55%) of individuals presenting SMCs. Memory complaints are recognized to be frequent  within the elderly population, especially among those with  depressive and anxiety symptoms. 19,20 In our study, depres- sion is very unlikely as an explanation for the high preva- lence of SMCs, since the presence of significant depressive  symptoms, based on the results from the Cornell scale, was  part of the exclusion criteria. SMCs have been more related to future cognitive de- cline rather than to current memory deficits. 2  Indeed, in a recent study, the presence of SMCs was found to be a sig- nificant predictor of subsequent decline, although without  a “dose-effect” relationship. 21  Moreover, in this same study  the investigators observed that the occurrence of SMCs also  increased the probability of an unstable diagnosis. We still  have no longitudinal data on the cognitive performance  of our study participants to be able to contribute to this  debate, but we may be able to re-evaluate at least part of the  sample in the future in order to replicate such observations.  An issue that has not been addressed in our study is the  Table 1. Demographic data, MMSE and MAC-Q scores from the  group of non-complainers and complainers.  Variable...

Ngày tải lên: 05/03/2014, 21:20

...

Ngày tải lên: 06/03/2014, 16:20

... being a Boer general in the war against England to becoming one of South Africa’s most distinguished politicians of the twentieth century. As well as a stint as Prime Minister of South Africa, ... Human Rights. 33 The appeal against Collins’ decision was heard and dismissed by the Court of Appeal. 34 My claim is not that the Court of Appeal’s decision was unequivocally wrong. Rather, it is ... book. They can rightly be seen as mediating between liberalism as an abstract political doctrine and an account of how judges are to decide cases in which the rule of law is at issue. Certainly, when...

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... also in quite ordinary situations, for example, claims that the rule of law does not apply to some ordinary exercises of official discretion. In addition, in seeing why ordinary exercises of official ... Australia, and Canada in order to show that law provides a moral resource that can inform a rule -of- law project capable of responding to situations which place legal and political order under great ... the claim that it is either dismal or at best ambiguous. Indeed, I will show that there is a plausible argument that when judges assert that they are maintaining the rule of law in exceptional situations,...

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... agudeza visual, grado de dificultad para caminar 300 metros, incapacidad para realizar las actividades cotidianas debido a problemas de salud en las 2 semanas pre- vias y seropositividad a Trypanosoma ... with a lower family in- come mentioned having more difficul- ties in paying for a medical visit, in making a medical appointment be- cause of existing lines, and in obtaining medicines because of ... medical diagno- sis of arthritis in the crude analysis, but these associations disappeared after adjustments for confounding variables. A previous medical diagnosis of coro- nary heart disease...

Ngày tải lên: 14/03/2014, 20:20

... answering the phone at state and local of ces. Include accurate information on what happened and what is being done. Pro- vide information about how the state and local associations are involved. ... teams Establishing a chain of command in advance of a crisis or emergency will help everyone know who is in charge and what the roles and responsibilities are when a crisis strikes. When assigning ... media in advance to establish mutually beneficial guidelines. Ask the media to: ● Refrain from replaying or reprinting images of the crisis. Showing dis- turbing pictures has the potential to...

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... role being playe d by inter-bank linkages in contagion. 16 9.3 Herding Linked to Manager ial Reputation Scharfstein and Stein (1990), Rajan (1994) modeled herding behavior based on managerial concerns ... countervailing effect over a set of parameters. In our paper, managers maximize bank profits, and yet there is herding. This suggests that aligning man- agerial objectives with maximization of bank ... channels examined in Acharya (2000). The herding aspect of our paper is related to the vast literature on he rding surveyed in Devenow and Welch (1996). In this literature, herding is often an...

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... effort has already been invested in mathematical modelling of the glycolytic pathway in yeast [3–8] and in other organisms, such as Trypanosoma brucei, the parasite that causes sleeping sickness ... metabolite concentration and flux are obtained from populations of yeast cells and so reflect an aggregate of the states of many individual organisms. Although no fitted model in this paper individually ... bayanus glycolytic flux control [49]. The evolutionary effort required to develop and maintain this set of biological checks and balances is intuitively indicative of some importance to maintaining...

Ngày tải lên: 17/03/2014, 11:20

... src="data:image/png;base64,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 4A+ K2J+AoA4D8IyOXLlr37zuy1H63ZmpdXMSPjgKslftUwJ6dps+bVsqtHIv7sAvDrlFRYWOhbAIAfHpML58/Lrl6j9Smn1D2xXkZm5r/dcH1u7uJFC2fNnLE1L699p04iEwBhCQC/LfF4/P0lSx4f+1gIoWevs4piMi8azcjMnDJ50qyZM9q271C5cpUNG9bPmjkjsdU 1A6 +f/sornbp0yTrq6K15eVWysopH5rMTn85p0rRTly4 1a9 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Ngày tải lên: 22/03/2014, 14:20

... AM, RESTA F et al. Serum Lp (a) is high in Healthy Centenarians. The 3 rd International Symposium: Multiple risk factors in cardiovascular disease. Vascular and organ Protection. Abstract Book-Florence: ... females divided into four age classes) from the town of Catania (Table I). Health state of our study series was evaluated by anamnesis, clinical examination and com- mon laboratory methods. We ... treatment due to insomnia, anxiety, articular pain and gas- trointestinal diseases, were excluded from the study, because of influences of various drugs on lipidic profile. The causes of institutionalization...

Ngày tải lên: 22/03/2014, 14:20