week 1 of human development days 1 7

... 12 7. 63 12 .68 10 4 .75 ±20.55 Diabetic control group 300.63 10 4.69a 244 .13 10 7. 03b 222 .75 10 4. 81 b 2 01. 38± 91. 64 b 209.50± 87. 61 a 203 .75 10 0.30 a 18 0.25 11 1.82 b Diabetic treated group 294 .13 ±89.97a ... 208 .13 76 .43 17 0.00 76 . 91 1.5h 98.38±24.44 15 0 .13 ±56.23 2h 93.88±30 .70 13 0.63± 47. 67c 2.5h 76 .75 ±33. 01 92.63±46 .12 d 3h 75 .38±34.99 87. 88±46 .76 c a Compared with normal control group P

Ngày tải lên: 25/10/2012, 11:10

... FEBS 66 21 Crystal structure of human ACMSD 10 11 12 13 14 15 16 17 18 19 20 S Garavaglia et al compounds in K562 cells but not in normal human lymphocytes Biosci Biotechnol Biochem 64, 11 42 11 46 ... Journal compilation ª 2009 FEBS 6 6 17 Crystal structure of human ACMSD A S Garavaglia et al His His His 17 4 Asp 2 91 w1 DHAP B Met 19 5 w1 w 268 DHAP Leu 296 w 51 C1 Trp 19 1 Phe 294 centre into a small ... 50, 76 0 76 3 Crystal structure of human ACMSD 40 Navaza J (20 01) Implementation of molecular replacement in AMoRe Acta Crystallogr D 57, 13 67 13 72 41 Murshudov GN, Vagin AA & Dodson EJ (19 97) Refinement...

Ngày tải lên: 18/02/2014, 06:20

... Ability of wild-type and mutant lysyl-tRNA synthetase to FEBS Journal 276 (2009) 611 8– 612 7 ª 2009 The Authors Journal compilation ª 2009 FEBS A P Mascarenhas and K Musier-Forsyth 13 14 15 16 17 18 19 ... variants of TRIM5a Proc Natl Acad Sci USA 10 1, 10 77 4 10 77 9 58 Yap MW, Nisole S, Lynch C & Stoye JP (2004) Trim5a protein restricts both HIV -1 and murine leukemia virus Proc Natl Acad Sci USA 10 1, 10 78 6 10 7 91 ... Musier-Forsyth LysRS 65 12 5 2 07 238 266 314 343 544 559 5 97 NH2 B N M1 AC C LysRS 1 70 M2 M3 COOH LysRS–CA Docking Model LysRS C3 M3 C2 C4 H7 M1/h7 M2 C1 AC Fig Domains of human lysyl-tRNA synthetase...

Ngày tải lên: 07/03/2014, 00:20

... inhibition of Table Effects of reducing agents on DS-dependent inhibition of NAT1 Conditions % of control activitya NAT1 NAT1 NAT1 NAT1 NAT1 NAT1 NAT1 NAT1 0.5 1. 2 1. 3 1. 9 0.4 0.9 1. 4 1. 6 a + + ... Cancer Res 13 , 15 40 15 51 Mushtaq A, Payton M & Sim E (2002) The C-terminus of arylamine N-acetyl transferase from Salmonella typhimurium controls enzymic activity J Biol Chem 17 , 12 175 12 1 81 FEBS ... M & Meyer UA (19 91) Monomorphic and polymorphic human arylamine 15 16 17 18 19 20 21 22 23 24 25 26 N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes...

Ngày tải lên: 07/03/2014, 02:20

... Strains W303-1B (mat a, ade2 1, ura3 1, his3 11 , trp1 1, leu2–3 ,11 2, can1 10 0), FYF4-A1 aco1 (mat a, ura3–52, trp1D63, leu2D1, his3D200, aco1::URA3), and BY 47 41 (mat a, his3, leu2, met15, ura3) ... stained Lane 1, recombinant human IRP1; lanes 2– 11 , fractions 1 10 of the sucrose gradient (B) Western blot of the same fractions Lane 1, recombinant human IRP1; lanes 2– 11 , fractions 1 10 of the ... m-hIRP1 production in the KGD1 mutant (B) Ultrastructural analysis of BY 47 41: KGD1 producing m-hIRP1 Two images are shown m, mitochondrion Bars ¼ 200 nm 10 88 FEBS Journal 274 (20 07) 10 83 10 92 ª 2007...

Ngày tải lên: 07/03/2014, 10:20

... point of view, the FEBS Journal 276 (2009) 377 0– 378 3 ª 2009 The Authors Journal compilation ª 2009 FEBS Human Ki -1 ⁄ 57 and pre-mRNA splicing G C Bressan et al A Ki -1/ 57 (12 2– 413 ) Ki -1/ 57 (15 1–263) ... GST, GST–hnRNPQ (1 443), GST–Ki -1 ⁄ 57 and the truncated constructs Ki -1 ⁄ 57 (12 2– 413 ), Ki -1 ⁄ 57 (15 1–260) and Ki -1 ⁄ 57( 2 61 413 ) fused to 6· His were expressed in Escherichia coli BL 21- CodonPlus-RIL ... FEBS Journal 276 (2009) 377 0– 378 3 ª 2009 The Authors Journal compilation ª 2009 FEBS 37 81 Human Ki -1 ⁄ 57 and pre-mRNA splicing 10 11 12 13 14 G C Bressan et al kin-associated Ki -1 (CD30) antigen...

Ngày tải lên: 16/03/2014, 02:20

... F7W, D11A, G13A, S15A, T17A, P19A, C22A, P37A, C38A, M43A, K47A, K47D, K47R, G49A, K50A, K50D, K50I, K50R, H51A, G52A, K55A, F64A, P74A, H77A, M79A, P82A, I84A, R86A, L91A, L101A, P 115 A, E 116 A, ... plasmids Strain W303-1A HHY13 UBHY-R HHY 212 d HHY 212 S UBHY-R 212 d Plasmid pBM–TIF51A YCpUB–R5A P 414 GAL1– heIF5A-1m Genotype Reference MATa leu2-3, 11 2his3 -11 , 15 ade2 -1 ura3 -1 trp1 -1 can1 -10 0 MATa leu2 ... ± 5.2 (K47A), 11 3.8 ± 10 .8 (K47R), 238 .7 ± 11 .3 (H51A), 14 4.5 ± 14 .2 (P74A), 15 0 .1 ± 12 .5 (L91A) and 444.0 ± 32.6 (L101A), whereas that for the strain expressing wild-type heIF5A was 11 2.3 ± 6.8...

Ngày tải lên: 16/03/2014, 06:20

... disulfide-linked component composed of peptides 11 3 12 6 [C1 (Cys 115 )] and 13 3 13 7 [C4 (Cys133)] (Fig 4) Corresponding peptide 11 3 12 6 (m/zcal ¼ 15 98 .7) and peptide 13 3 13 7 (m/zcal ¼ 646.2) were detected ... patch consisting of Trp134, Leu138, Phe1 41 and Pro142 Leu138 and homologues of Trp134 and Phe1 41 are conserved throughout the Cripto family [1] and are clustered on the side of the CFC domain ... analysis of the EGF-CFC 15 16 17 18 19 20 21 22 23 family member Cripto identifies residues essential for nodal signalling Development 12 8, 45 01 4 510 Saloman, D.S., Bianco, C & De Santis, M (19 99)...

Ngày tải lên: 23/03/2014, 21:20

... ± ± ± ± ± 2.32 0 .14 1. 29 0.23 0.56 0.54 0. 079 0 .14 5 0.033 0 .11 0 ± ± ± ± 0.0 27 0.038 0. 018 0.023 0 .11 5 0 .19 1 0.033 0 .14 7 ± ± ± ± 0.029 0.0 27 0.008 0. 019 0 .18 7 0.248 0.059 0 .11 7 ± ± ± ± 0.048 0.039 ... repel NOE 20 .76 0.49 16 . 91 1.95 0.60 0.80 ± ± ± ± ± ± 1. 36 0.08 0.65 0 .15 0.39 0. 51 20.04 0.42 16 .80 1. 92 0.35 0.55 ± ± ± ± ± ± 0.64 0.04 0. 41 0. 07 0.23 0 .15 22.48 0. 57 17 .95 2 .12 0.94 0.90 ± ... (pm) 0 .12 ± 0. 01 angles (degree) 0.44 ± 0. 01 impropers (degree) 21. 58 ± 2.68 NOE (pm) 1. 1 ± 0.3 0 .11 0.44 18 .48 1. 2 ± ± ± ± 0.02 0. 01 3. 37 0.2 0 .13 0.45 20.80 1. 3 ± ± ± ± 0.02 0.02 4 .76 0.4 F,Y...

Ngày tải lên: 24/03/2014, 04:21

... 0 .19 0 .18 5 0 .18 5 0 .16 0 . 17 0 .15 0 .16 5 0 .14 0 .16 20 30 40 50 60 70 80 90 Absorbance at 295 nm 0 . 17 5 0 .18 0 .16 5 0 . 17 5 0 .16 0 . 17 0 .16 5 0 .15 5 0 .13 0 .16 0 .15 20 30 Temperature (°C) D 0 .18 0.2 0 .19 2 ... effect of loop length and sequence on the folding topology J Am Chem Soc 13 1, 16 824 16 8 31 50 Phan AT (2 010 ) Human telomeric G-quadruplex: structures of DNA and RNA sequences FEBS J 277 , 11 07 11 17 ... by TKQ1 For the spectrum of TKQ2, very little signal A 14 .0 13 .0 12 .0 11 .0 10 .0 p.p.m 13 .0 12 .0 11 .0 10 .0 p.p.m B 14 .0 Fig NMR spectroscopy Imino proton spectra of: (A) TKQ1 (top) and TKQ1m (bottom);...

Ngày tải lên: 29/03/2014, 21:20

... BE (19 91) Bell-shaped calcium-response curve of Ins (1, 4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum Nature 3 51, 7 51 75 4 13 Finch EA, Turner TJ & Goldin SM (19 91) ... FASEB J 10 , 15 05 15 17 15 Berridge MJ (19 98) Neuronal calcium signaling Neuron 21, 13 –26 16 Yoo SH & Jeon CJ (2000) Inositol 1, 4,5-trisphosphate receptor ⁄ Ca2+ channel modulatory role of chromogranin ... protein of secretory granules J Biol Chem 275 , 15 0 67 15 073 17 Kloda A, Ghazi A & Martinac B (2006) C-terminal charged cluster of MscL, RKKEE, functions as a pH sensor Biophys J 90, 19 92 19 98 18 Bolduc...

Ngày tải lên: 29/03/2014, 23:20

... Journal 276 (2009) 11 14 11 24 ª 2009 Hunan Normal University Journal compilation ª 2009 FEBS 11 15 SP1 and AP-2a regulate KCTD10 R Liu et al A B Fig Genomic structure of human and mouse KCTD10 genes, ... R (19 94) A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII 110 component of the Drosophila SP1 and AP-2a regulate KCTD10 16 17 18 19 20 21 22 23 24 25 26 27 28 ... model – AP-2 FEBS Journal 276 (2009) 11 14 11 24 ª 2009 Hunan Normal University Journal compilation ª 2009 FEBS 11 19 SP1 and AP-2a regulate KCTD10 R Liu et al Fig Effects of Sp1 and AP-2a expression...

Ngày tải lên: 30/03/2014, 02:20

Ngày tải lên: 12/05/2014, 21:54

... infections Nat Med 2008, 14 :10 77 -10 87 doi: 10 .11 86 /14 79 -5 876 -8-49 Cite this article as: Ricci et al., Toll-like receptor polymorphisms influence mother-to-child transmission of human immunodeficiency ... 1. 06 GG Haplotypes AA AG 0. 21 0.23 0.86 0.46 1. 62 0.65 1. 30 G;A 0.53 0. 51 A;G 0.44 0.36 0.92 0.20 0.63* A;A 0.02 0. 07 3 .16 1. 24 8.03 0. 016 * G;G 0. 01 0.06 5.54 1. 76 17 .50 0.0038* LCL, lower confidence ... risk of HIV -1 infection, the [G;G] haplotype remained associated with a higher risk of MTCT of HIV -1 after adjustment for maternal viral load (OR = 10 .04, 95% CI 1. 70 -59. 37, p = 0. 012 ; p = 0. 0 17 ...

Ngày tải lên: 18/06/2014, 16:20

... HPIV1 wt rHPIV1-CR84G rHPIV1-CR84GHNT553A rHPIV1-C 17 0 rHPIV1-LY942A rHPIV1-CR84GHNT553ALY942A rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Mean sum of ... rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Virus titer ± S.E at 32°C b 35°C 36°C 37 C 38°C 39°C 40°C Shut-off (°C) d 7. 7 ± 0 .1 9.2 ± 0.4 7. 8 ± 0 .1 7. 9 ... rHPIV1-CR84G/ 17 0HNT553ALY942A and rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 vaccine candidates reached peak titers of 7. 9 and 7. 2 log10 TCID50/ml, respectively, in Vero cells (Figure 1) The level of 17 0HNT553ALY942A...

Ngày tải lên: 18/06/2014, 18:20

... Reference HCV HCV HCV HCV HIV HIV HIV HHV-6 HHV-6 HCV 9 .1 HCV 9.2 HCV 10 .1 HCV 10 .2 Con-1f1 Con-1r1 Con-1r2 U16 - 17 F U16 - 17 R gac act cca cca tag atc act c cat gat gca cgc tct acg aga c ctg tga ... of a new virus, HBLV, in patients with lymphoproliferative disorders Science 19 86, 234( 477 6):596-6 01 Page of (page number not for citation purposes) Virology Journal 20 07, 4 :10 6 11 12 13 14 15 ... 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Salahuddin SZ, Rose RM, Groopman JE, Markham PD, Gallo RC: Human T lymphotropic virus type III infection of human alveolar macrophages Blood 19 86,...

Ngày tải lên: 18/06/2014, 18:20

... 2.5 15 IM28 (ug/ml) Figure IM28 on fusion of TF228 .1. 16 cells with SupT1 cells Effect of3 Effect of IM28 on fusion of TF228 .1. 16 cells with SupT1 cells TF228 .1. 16 cells were mixed with SupT 11 cells ... citation purposes) Virology Journal 2005, 2:9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 and for LESTR/fusin and blocks HIV -1 entry Nature 19 96, 382:829-33 Cocchi F, DeVico AL, Garzino-Demo ... TF228 .1. 16 Effect of IM28 and dexamethasone on SupT1 cells co-cultured with TF228 .1. 16 Zoom of negative photomicrograph of SupT1 cultures co-cultivated with TF 228 .1. 16 cells (A) in the presence of...

Ngày tải lên: 18/06/2014, 22:20

... the study, analyze data and assist in the preparation of the manuscript http://www.jneuroinflammation.com/content/2 /1/ 15 10 11 12 13 14 15 Acknowledgements We thank Sara Medgysi for assistance ... 277 :32046-32053 Page of (page number not for citation purposes) Journal of Neuroinflammation 2005, 2 :15 20 21 22 23 24 25 26 27 28 29 30 31 32 http://www.jneuroinflammation.com/content/2 /1/ 15 ... Neurobiol 19 95, 21: 290-3 01 Das S, Potter H: Expression of the Alzheimer amyloid-promoting factors 1- antichymotrypsin and apolipoprotein E is induced in astrocytes by IL -1 Neuron 19 95, 14 :4 47- 456...

Ngày tải lên: 19/06/2014, 22:20

... of 10 10 0 μg/L IGF -1 in the presence of 10 % FBS Page of 11 (page number not for citation purposes) Journal of Orthopaedic Surgery and Research 2006, 1: 9 http://www.josr-online.com/content /1/ 1/9 ... under 10 %FBS conditions The morphology of human NP cells under 10 %FBS conditions 10 %FBS, 10 0 μg/L IGF -1, the morphology of NP cells were similar to the 10 μg/L TGF- 1 group ( 10 0) Figure 11 The ... concentration of 10 0 μg/L IGF -1 compared to controls(50.6%) Dose-dependent effects of TGF 1 and IGF -1 on cell proliferation were found between 1 http://www.josr-online.com/content /1/ 1/9 10 μg/L and 10 10 0...

Ngày tải lên: 20/06/2014, 00:20

... HPIV1 wt rHPIV1-CR84G rHPIV1-CR84GHNT553A rHPIV1-C 17 0 rHPIV1-LY942A rHPIV1-CR84GHNT553ALY942A rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Mean sum of ... rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Virus titer ± S.E at 32°C b 35°C 36°C 37 C 38°C 39°C 40°C Shut-off (°C) d 7. 7 ± 0 .1 9.2 ± 0.4 7. 8 ± 0 .1 7. 9 ... rHPIV1-CR84G/ 17 0HNT553ALY942A and rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 vaccine candidates reached peak titers of 7. 9 and 7. 2 log10 TCID50/ml, respectively, in Vero cells (Figure 1) The level of 17 0HNT553ALY942A...

Ngày tải lên: 20/06/2014, 01:20