... and AngII, whether up-regulation of Cx43 can
be antagonized by AT1 antagonists or whether sup-
pressed smooth muscle cell proliferation and migra-
tion by AT1 antagonists are mediated through ... seamless connections.
The present study aimed to detect the expression
of Cx40 and Cx43 in the artery at early stage of high
fat diet induced atherosclerosis and to investigate the
effects of AT1 ...
Introduction
Atherosclerosis is a slow and complicated pa-
thological process. Vascular smooth muscle cell
(VSMC) proliferation is one of the important features
of atherosclerosis. The gap junction...
... point the object to an URL,
provided the system has set it up in a consistent manner. This is another way that
ADO allows developers to read outside data, such as from other applications or ... other applications or
over the Internet. You could not do this easily with DAO.
Figure A.1. The object model for ActiveX Data Objects 2.7.
Most of the work is done in the ADODB module when you ... Recordset object. Similar to the DAO Recordset object, you can open the
Recordset objects as read-only or dynamic. Each Recordset object also has a
Fields collection.
ã Stream object. This object...
... that
you can use to accomplish tasks in your applications.
You can see how these APIs are used in Figure 7.3.
Figure 7.3. Under the covers, the SQL-DMO objects are being used to perform the ...
Lookingatthe SQL Server DMF APIs
The SQL Distributed Management Framework is a framework of objects, services, and
components used to manage Microsoft SQL ... is a brief description of each of the APIs. We will be using the last two directly
in the rest of this chapter.
ã SQL-NS. SQL Namespace provides a way to actually call the Enterprise Managers...
... discussion
From the land cover data and vegetation-
related parameters in the Nong Son catchment,
and the monthly meteorological data atthe Tra
My climate station for the period of 1980-2004,
the ... area, there are only four rain
gauges, among those only one collects hourly
data; one climatic station at Tra My; and one
discharge gauge at Nong Son. In general, the
hydro-meteorological station ... calculated by the Penman-Monteith
equation, known as the one-step method. The approach requires data onthe land cover and related-
vegetation parameters based on AVHRR and LDAS information, which...
... include the International Conference on
Population and Development Programme of Action (ICPD
PoA,1994), the Beijing Declaration and Platform for Action
(BPfA, 1995), the Convention onthe Elimination ... ensure international commitments, such as those
stated in the Convention onthe Elimination of All Forms of
Discrimination Against Women (CEDAW), International
Conference on Population and Development ... death and disability.
e SPRINT Initiative, led by the International
Planned Parenthood Federation (IPPF) in collaboration
with the United Nations Population Fund (UNFPA) and
other national...
... suppression:
are other autophagy regulators also tumour suppres-
sors? One would expect that this would be the case
but, so far, only one of the many other proteins impli-
cated in autophagy regulation ... by
the independent identification of BIF-1, an interactor
of UVRAG, as a regulator of autophagy [5]. On the
other hand, monoallelic UVRAG mutations associated
with microsatellite unstable colon ... of the
forming invagination, thereby securing the inclusion of
cargo proteins within ILVs [60]. The main link between
PI3K-III and the ESCRT pathway is the fact that
Vps27 ⁄ HRS, a core component...
... explained by their stimulatory
effect onthe endothelial generation of PGI
2
and NO
ã
.
There are other propositions concerning the mechan-
ism of endothelial actions of statins, e.g. the induction
of ... endothelial dysfunction in patients with
atherosclerosis [8]. The great expectations for the
therapeutic use of antioxidants in patients with athero-
sclerosis need to be re-examined.
Endothelium ... appreciated
than it should have been. Atthe time, Bk was per-
ceived as a mediator of pain and inflammation respon-
sible for paralytic vasodilatation in the course of acute
pancreatitis. The reasoning...
... indicated that the aorta–
gonad–mesonephros (AGM) region of the embryo is a
primary source of definitive hematopoietic progenitors
[32,33]. These subsequently enter the circulation and
colonize the ... (and other hematopoiesis-sup-
porting organs), where they mature before migrating
to the bone marrow [34,35]. Definitive hematopoiesis
is initiated in the aortic endothelium region of the
embryonic ... Quantitative
developmental anatomy of definitive haematopoietic
stem cells ⁄ long-term epopulating units (HSC ⁄ RUs): role
of the aorta–gonad–mesonephros (AGM) region and
the yolk sac in colonisation...
... is the phosphatase that
dephosphorylates Cdh1. Its inactivation has the most
dramatic effect on Clb cyclin degradation. CDC15 is a
component of one of the two pathways that activate
Cdc14. In ... components that function atthe top of the path-
way are located? She found that Tem1 (and we now
know all other MEN components) localized to the
SPB that migrates into the bud during anaphase. The
MEN ... the
machinery that promotes Cdc14 activation [54].
Cdc14 – more than just promoting CDK
inactivation
A question that arises from the observation that at
least two pathways control Cdc14 localization is...
... duplication events, followed by the evolution of
specialized gene functions, as well as by the creation
and loss of different exons. Both the emergence of
additional genomic copies by gene duplication ... between the U2AF-related proteins imply
that they have evolved distinct functions in relation to
the control of gene expression in complex organisms.
Clues to the biological processes in which these ... participate may be obtained by determining their
tissue expression patterns, elucidating their RNA-bind-
ing specificities, and identifying the genes that they
control. Ultimately, understanding the...
... considers the bodies
of managers, how they embody the desired aesthetic of the organization, and how
they produce and are consumed by the organization. Pelzer (2002) looks at the
disgust that ... traditional intellectual approaches, but one method usually
predominated. Onthe content continuum, at one end is instrumental content that
considers mainstream organizational research questions ... that would seem to
qualify, we think that that is not all that qualifies. To consider this further, let us look
at the idea of aesthetics as connection. Bateson (1979) suggested that by aesthetic
he...
... roles
in the complex network that controls cell growth and
proliferation, the elucidation of the molecular path-
ways that transmit information onthe growth state of
a cell population to the Pol ... phosphorylated by ERK permits Pol I
elongation, whereas hypophosphorylated UBF inhibits
elongation, demonstrating that transcription elongation
Growth factors
Nutrients
Oncogenes
Nutrients
Oncogenes
Genotoxic
Tumor ... proliferation, stimulates
Pol I transcription in part through phosphorylation of
the C-terminal activation domain of UBF [28], under-
scoring the importance of UBF phosphorylation in the
control...
... grastrulation, sup-
porting the scaling of the BMP activation gradient
itself [20].
How is the BMP activation gradient generated? The
key asymmetry is the localized secretion of BMP
antagonists by the ... facilitating the evolutionary adapta-
tion of body size, because the pattern will automati-
cally adjust with any mutation that alters body size,
without the need for further adjustment of the pattern-
ing ... Driesch and
Morgan atthe end of the 19th century [45,46]. In addi-
tion to natural variation, size is regulated also by the
availability of nutrients or other growth conditions.
Drosophila larvae...
... preventing the formation of the
competing Orp1 Cys36-Cys82 disulfide bond. Once
activated, the Yap1 NES that lies within the c-CRD is
masked leading to its retention in the nucleus and the
up-regulation ... anion generator, was shown to operate. Under
conditions favouring superoxide anion generation, Yap1
is activated by H
2
O
2
formed by the dismutation of the
A
B
Fig. 1. (A) Comparison of the ... also for the res-
toration of gene expression upon osmo-adaptation,
controlling the extent of gene expression as well as its
duration [48]. Recently, Hog1 has been found to be
located at several...