wakefulness variability and assessment in patients with impaired consciousness

... studies examining natriuretic peptide levels and/ or inflammatory markers during inotrope administration with inconsistent results [8-11] Adding complexity to this picture is data indicating that ... all patients care continued to be at the discretion of the attending physician, including inotrope administration and dosing It is well recognized that heart failure leads to increased circulating ... competes with membrane-bound Fas for ligand binding, therefore reducing apoptotic signaling Procedures All treatments including milrinone dosing was at the discretion of the patient's attending physician,...

Ngày tải lên: 18/06/2014, 15:20

... combined navelbine and mitoxantrone, supporting the testing of combination therapy with estramustine, mitoxantrone, and vinorelbine in patients with CRPC One study demonstrated a potential clinical benefit ... treatment with vinorelbine, mitoxantrone and estramustine yielded a response rate suggesting clinical activity in men with CRPC, and was well tolerated The combination of CRA/IFN and paclitaxel, in ... Survival in patients treated with mitoxantrone, estramustine and vinorelbine (Arm A) or 13-cis retinoic acid, interferon-alpha2b with paclitaxel (Arm B) Figure Progression Free Survival in patients...

Ngày tải lên: 18/06/2014, 16:20

... filgrastim Median values and interquartile range are shown *p < 0.05 compared with baseline **p < 0.01 compared with baseline Panel C: Boxes and whiskers depicting median values and interquartile range ... treated with either pegfilgrastim or daily filgrastim In both cohorts of patients, cytokine administration translated into increased percentages of DC1 and DC2 cells, albeit with a different kinetics ... filgrastim in the human setting [34] In this study, daily treatment with G-CSF for weeks was correlated with an increase of IL-10-secreting type Treg cells in the peripheral blood and with the...

Ngày tải lên: 18/06/2014, 16:20

... beginning of the intervention), immediately post training (within one week after the last training session) and four weeks after the completion of the training (follow-up assessment) Each training ... posture and balance with increasing difficulty and complexity These included: (1) static posture control-achieving better upright position while sitting and in standing (improving upper limb and ... training was generally interesting and challenging in regards to the motor and balance demands Three patients also mentioned that the training required concentration and attention abilities in...

Ngày tải lên: 19/06/2014, 08:20

... computed by assigning points to "very much", points to "a lot", point to "a little", and points to "not at all" The means, standard deviations, maximum values, and minimum values are shown in Table Reliability ... frequent clinic visits and decorative cosmetics can improve QOL [6,7] Still, less attention has been given to the QOL of patients with acne in Japan than in other countries In looking for instruments ... created by Finlay et al [9,10] The DLQI is short, and it has been used internationally for more than 10 years in the assessment and comparison of QOL of patients with acne, eczema, psoriasis, and other...

Ngày tải lên: 20/06/2014, 15:20

... verified by studies performed with patients with respiratory failure, with depression being observed in 30% of patients with moderate failure and in 50% in patients with severe obstructive pulmonary ... suffocating disease status may explain the high percentage of depression in patients with COPD and BA in the study, which was higher than the percentage reported in studies performed with in- patients ... clinical experience accepts high comorbidity in pulmonary patients, studies assessing and comparing anxiety and depression levels among patients with different pulmonary diseases are lacking in...

Ngày tải lên: 08/08/2014, 23:20

... outcome in 160 patients with GBM treated with radiation and temozolomide IDH1 mutations occur in approximately 60 – 80 % of diffusely infiltrating gliomas of the WHO grades II and III and in secondary ... analyzing different chemotherapeutic combinations, substances such as cisplatinum might inactivate or attenuate MGMT-status thus influencing the clinical outcome when combined with alkylating chemotherapies ... only in around % of primary GBM (11;18-22) In our series we identified in of 140 patients (3 %) IDH-1 mutations Currently, it remains unclear if at least some of the patients with clinically defined...

Ngày tải lên: 09/08/2014, 09:21

... obtained in clinical trials [4] Lumiracoxib is a novel, selective cyclo-oxygenase-2 (COX-2) inhibitor for the treatment of OA and acute pain In two 13week, international, multicentre, double-blind ... lumiracoxib 100 m god (with and without a 200-mg od initial dose for the first weeks) and celecoxib 200 mg od compared with placebo according to the percentage of patients achieving PASS or MCII thresholds ... Symptom State; SD, standard deviation was exceeded and subsequently maintained during consecutive visits until week 13 (inclusive) Missing data were not imputed Only patients with consecutive visits...

Ngày tải lên: 09/08/2014, 10:20

... closely linked to angiogenesis [63] and cannabinoids inhibit angiogenesis in tumours [37,64] Conclusion In summary, cannabinoid CB1 and CB2 receptor protein and RNA and the endocannabinoids AEA and ... distribution and few or no inflammatory cells; = mild inflammation: synovial intima three to five cells thick with slight increase in cellularity and with few inflammatory cells; = moderate inflammation: ... treatment of inflammatory pain in OA and RA patients using NSAIDs may be targeting endocannabinoid metabolism in addition to arachidonic acid metabolism These interactions may be of great clinical...

Ngày tải lên: 09/08/2014, 10:23

... APRIL and BAFF in CSF of systemic lupus erythematosus (SLE) patients, (d) APRIL and BAFF in serum of SLE patients, (e) IL-6 and APRIL in CSF of SLE patients, and (f) IL-6 and BAFF in CSF of SLE patients ... antibody-inducing cytokine APRIL in the CNS of NPSLE patients compared with SLE patients without CNS involvement Elevated levels of IL-6 in CSF have been reported in NPSLE patients [40] and could ... Aleman-Hoey D, Alarcon-Segovia D: Interleukin1 and interleukin-6 activities are increased in the cerebrospinal fluid of patients with CNS lupus erythematosus and correlate with local late T-cell activation...

Ngày tải lên: 09/08/2014, 10:23

... grafting (CABG) were included in the study; patients with an additional left ventricular remodeling procedure were excluded The study population included 20 male and 20 female patients with a ... five patients died from not heart failure-related causes: pneumonia with sepsis in two cases, stroke, cerebral bleeding and cancer complicated with intestine perforation in one patient In one ... replacement with CABG and in one a combination of MV repair, CABG and TV repair Redo's and prolonged cross-clamping times Figure (MVR) – Meier survival curve in (HTX) Kaplan and heart transplantation patients...

Ngày tải lên: 10/08/2014, 10:20

... conducted by Diaz-Peromingo et al., who also didn’t find any relationship between Lp(a) levels and AF [13] They compared 101 patients with AF and 101 patients with sinus rhythm in control group They ... Lipoprotein(a) binds and inactivates tissue factor pathway inhibitor: a novel link between lipoproteins and thrombosis Blood 2001, 98:2980-7 Kim SM, Lee JH, Kim JR, Shin DG, Lee SH, Cho KH: Female patients ... participated in the design of the study and in the manuscript preparation and revision All authors read and approved the final manuscript Competing interests The authors declare that they have no competing...

Ngày tải lên: 11/08/2014, 07:21

... domains (i.e., working memory, verbal memory, and processing speed) and discrete domains of functioning (i.e., QLS Instrumental, QLS Intrapsychic, and QLS Interpersonal) at baseline and following ... cognition, including working memory, processing speed, and verbal memory as the independent variables; 2) PANSS Neg and PANSS Pos as intermediate outcomes; and 3) of functional domains, including QLS Instrumental, ... correlated with certain domains of functioning The direct and indirect relationships observed among cognition, symptoms and the three subdomains of functioning at baseline are illustrated in the...

Ngày tải lên: 11/08/2014, 17:20

... devices and techniques d350 Conversation x Changing and maintaining body position d410 Changing basic body position x d415 Maintaining a body position x x x Carrying moving and handling objects ... d430 Lifting and carrying objects d440 Fine hand use x x x Walking and moving d450 Walking x x x d455 Moving around x x x d460 Moving around in different locations x d465 Moving around using equipment ... hiking and cycling ( )" quitting hiking quitting cycling d920 Recreation and leisure (incl d9201 Sports) d475 Driving (incl d4750 Driving humanpowerded transportation) Mueller et al Health and...

Ngày tải lên: 12/08/2014, 01:21

... coordinating the study and in the interpretation of data and were involved in drafting the manuscript JP was involved in the interpretation of the data and revised the manuscript for important intellectual ... higher plasma lactate and glucose levels and increased insulin needs in comparison with the phosphodiesterase III inhibitor milrinone The use of adrenaline – in contrast to milrinone – leads to delayed ... hyperlactatemia, and treatment with adrenaline has been described in a variety of settings, including healthy volunteers [14] and patients with sepsis and septic shock [15] Additionally, Totaro and colleagues...

Ngày tải lên: 13/08/2014, 03:21

... 450) mg; and midazolam, (2 to 3) mg Eighty-four patients were intubated in the ICU and 75 were intubated in areas outside the ICU, mostly in an operating theatre or the Available online http://ccforum.com/content/11/3/R56 ... hundred forty-nine (94%) patients were intubated within six hours of ICU admission and eight others were intubated within 24 hours of admission All 159 patients were intubated because of septic ... available for the remaining 16 patients We excluded 33 patients from analysis In 13, we could not identify the induction agent that had been used, and 10 had been intubated in another hospital...

Ngày tải lên: 13/08/2014, 03:21

... of scapular pain in patients with cervical radicular pain In the 64 patients with painful cervical nerve roots, 33 (51.6%) reported pain in the scapula area, and 31 (48.4%) did not In subjects ... across patients with cervical or lumbar radicular pain and is useful in diagnosis We set out to investigate these questions by assessing the pain drawings and verbal descriptions of pain location and ... may represent referred pain from the disk itself The quality of pain is generally an insensitive and non-specific finding in patients with nerve root pain 11 Competing interests 14 12 13 The authors...

Ngày tải lên: 13/08/2014, 14:20

... ill patients were admitted (in fact, missing urine output was significantly and independently associated with increased mortality; data not shown) In some other cases, exact urine output recording ... one missing urinary output was 51.2% (21/41), in comparison with 16.8% (15/89) in the remaining patients (P < 0.001) Polyuria was detected in 34.4% (327/950) of ICU days, and occurred in 76.0% ... aimed at investigating the incidence and clinical significance of hypernatremia occurring during the course of the ICU stay in a large series of patients with severe TBI The study shows that, in the...

Ngày tải lên: 13/08/2014, 16:21

... lung and chest wall mechanics, alveolar recruitment, and gas exchange in ALI/ARDS patients with increased IAP compared with patients with normal IAP [7] More recently, in a study including mainly ... small PEEP-induced increase in IAP is in keeping with previous findings by de Keulenaer and colleagues [37] Gattinoni and colleagues [7] reported a reduction in the Estat, RS, Estat, L and Estat, ... gas exchange and hemodynamics in ALI/ARDS patients with normal IAP or IAH However, PEEP significantly increased EVLWI in patients with normal IAP but not in patients with IAH IAH, within the limits...

Ngày tải lên: 13/08/2014, 19:20

... criteria (ie rise in serum creatinine to ≥ 354 μmol/L or rise in serum creatinine by >300% from baseline within 48 hours) who were not treated with RRT We also recorded whether patients had evidence ... oliguric with a urine output less than 400 ml/day and would have (probably) fulfilled the urine criteria for AKI stage III The remaining 583 patients had RRT without a 300% change in creatinine or ... Kellum JA, Beginning and Ending Supportive Therapy for the Kidney (BEST Kidney) Investigators: Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute...

Ngày tải lên: 13/08/2014, 19:20