virology and molecular epidemiology of respiratory syncytial virus rsv

... Pathogenesis of respiratory syncytial virus infection Viral Immunol 2004, 17(2):165-81 Tripp RA, Ed: Pneumovirus and Metapneumovirus: respiratory syncytial virus and human metapneumovirus In Topley and ... PA, Pringle CR: Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus Virus Res 1996, 43(2):155-61 Falsey AR: Respiratory syncytial virus infection in adults ... 24 h pi to 48 h pi RSV stimulation of SOCS1, SOCS3, IFNα and IFNβ protein expression To determine if the type I IFN and SOCS mRNA expression profiles in RSV and RSV mutant virus infected cells...

Ngày tải lên: 20/06/2014, 01:20

... characterization of the clinical RSV strains ST recruited patients and collected clinical samples OT was responsible for the molecular characterization of some of the RSV clinical isolates GS and LHG ... The histopathology of fatal untreated human respiratory syncytial virus infection Mod Pathol 2007, 20(1):108-119 32 Neilson KA, Yunis EJ: Demonstration of respiratory syncytial virus in an autopsy ... the exception of BT4a at MOI Average RSV A2 titers peaked at 5.25 and 5.70 log10 TCID50/ml for MOIs of 0.1 and 5, respectively In comparison, peak average titers for RSV BT2a, BT3a and BT4a after...

Ngày tải lên: 11/08/2014, 21:22

... modulation of viral antigens from infected cells: biological and molecular studies of measles virus infection and implications for understanding virus persistence and receptor diseases In Animal Virus ... Participation of cytoskeletal intermediate filaments in the infectious cycle of human respiratory syncytial virus (RSV) Virus Res 1988, 9(4):307-321 Valdovinos MR, Gomez B: Establishment of respiratory syncytial ... endocytosis of RSV Ag-Abs Reduction of RSV Ag-Abs concentration on the cell-membrane was evidenced at both 30 and 50 minutes of incubation with anti -RSV IgG (Fig 2C and 2E) implying that RSV Ag-Abs...

Ngày tải lên: 18/06/2014, 18:20

... severity of acute RSV disease, and that RSV clinical disease can be modified with the use of a specific anti -RSV neutralizing antibody directed against a well conserved epitope of the RSV F protein ... concentrations, and more importantly with no evidence of AO in these mice suggesting a pivotal role of INF-γ in the pathogenesis of RSV disease Page of (page number not for citation purposes) Virology ... of IL-1α, IL-12p70, TNF-α and IFN-γ and serum IL-10 and KC were significantly lower in mice treated with motavizumab compared with RSV- infected untreated mice (Table 1) The role of TNF-α in RSV...

Ngày tải lên: 18/06/2014, 18:20

... modulation of viral antigens from infected cells: biological and molecular studies of measles virus infection and implications for understanding virus persistence and receptor diseases In Animal Virus ... Participation of cytoskeletal intermediate filaments in the infectious cycle of human respiratory syncytial virus (RSV) Virus Res 1988, 9(4):307-321 Valdovinos MR, Gomez B: Establishment of respiratory syncytial ... endocytosis of RSV Ag-Abs Reduction of RSV Ag-Abs concentration on the cell-membrane was evidenced at both 30 and 50 minutes of incubation with anti -RSV IgG (Fig 2C and 2E) implying that RSV Ag-Abs...

Ngày tải lên: 20/06/2014, 01:20

... severity of acute RSV disease, and that RSV clinical disease can be modified with the use of a specific anti -RSV neutralizing antibody directed against a well conserved epitope of the RSV F protein ... concentrations, and more importantly with no evidence of AO in these mice suggesting a pivotal role of INF-γ in the pathogenesis of RSV disease Page of (page number not for citation purposes) Virology ... of IL-1α, IL-12p70, TNF-α and IFN-γ and serum IL-10 and KC were significantly lower in mice treated with motavizumab compared with RSV- infected untreated mice (Table 1) The role of TNF-α in RSV...

Ngày tải lên: 20/06/2014, 01:20

... Number of RSV positive patients Figure Seasonal1occurrence of respiratory syncytial virus infections (number of cases) in Croatia (1994–2005) Seasonal occurrence of respiratory syncytial virus ... detections of RSV and another virus in 0.4% The mean age of recruited patients was 13.4 months (SD = 18.7) and was similar in the virus negative and all the virus positive groups reported An analysis of ... detection of RSV, adenovirus, influenza virus (type A and B) and parainfluenza virus (type 1–3) by direct fluorescence assay (DFA, Light Diagnostics, Chemicon International, Inc., Temecula, CA) and...

Ngày tải lên: 20/06/2014, 01:20

... region of the S1 gene of infectious bronchitis virus Arch Vrol 2000, 145, 291-300 Yu L, Wang Z, Jiang Y, Low S, Kwang J Molecular epidemiology of infectious bronchitis virus isolates from China and ... identities of 97∼ 98% and amino acid sequence identities of 96∼98% with Chinese IBVs (strain A2, SH and QXIBV) Discussion One of the major problems of IBV is the frequent emergence of new variants ... der Zeijst BAM Phylogeny of antigenic variants of avian coronavirus IBV Virology 1989, 169, 217-221 15 Lee CW, Hilt DA, Jackwood MW Redesign of primer and application of the reverse transcriptase-polymerase...

Ngày tải lên: 07/08/2014, 23:22

... Jameel S Molecular virology of hepatitis E virus Virus Res 2011, doi:10.1016/j.virusres.2011.02.011 18 Yan Y, Zhang W, Shen Q, Cui L, Hua X: Prevalence of four different subgenotypes of genotype ... years and, in Shanghai, have now become the third most likely cause of hepatitis disease after hepatitis A and B [21] Consequently, more molecular epidemiology investigations of HEV among swine, and ... least three genotypes (1, and 4) and nine subtypes (1b, 1c, 3b, 4a, 4b, 4d, 4g, 4h and 4i) of human and swine HEV have so far been documented in China Since genotype and the newly identified subtype...

Ngày tải lên: 11/08/2014, 21:22

... positive and negative sense RSV RNA standards into naïve mouse lung RNA and using both positive and negative strand-specific reagents to measure RSV RNA The detection of non-specific RNA strand in ... the molecular and cellular studies and drafted the manuscript DR carried out the in vivo and cellular assays and analysis and interpretation of data, EJM, MW and CL participated in the design of ... Therapy of respiratory syncytial virus infection Pediatr Infect Dis J 2000, 19:786-790, discussion 802-784, 811-783 Greenough A, Thomas M: Respiratory syncytial virus prevention: past and present...

Ngày tải lên: 12/08/2014, 01:22

... sequences of the Korean JEV strains showed remarkable genetic stability Five pairs of E gene sequences from 10 Korean strains (K83P34 and K88A07, K84A071 and K87A071, K93A07 and K96A07, K94A07 and ... experiments and contributed to the preparation of the manuscript JEC, SYK, JR, and WYC collected the specimens and contributed to the data analysis YRJ and MGH contributed to the data analysis and the ... Yun et al Virology Journal 2010, 7:127 http://www.virologyj.com/content/7/1/127 Page of once a week in cattle sheds and the mosquitoes were identified morphologically and categorized to...

Ngày tải lên: 12/08/2014, 04:20

... mode of spread was not known and therefore were sporadic The foremost mode of contamination in patients with HCV genotype 3a and 3b was multiple use and re-use of needles/syringes that was 70% and ... of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma J Clin Microbiol 1992, 29:2528-2534 17 Idrees M: Common genotypes of hepatitis C virus ... 0 28 Ali et al Virology Journal 2010, 7:203 http://www.virologyj.com/content/7/1/203 Page of Table Potential routes of transmission of various HCV genotypes HCV Possible routes of transmission...

Ngày tải lên: 12/08/2014, 04:20

... caused by respiratory syncytial virus in Croatia in 2006 and 2007 by viral subtype and age Bronchiolitis and pneumonia (No.) caused by respiratory syncytial virus in Croatia in 2006 and 2007 by ... Biosystems) The N gene of RSV A and of RSV B were targeted with primers and probes (as listed below), according to van Elden et al [19], with minor modifications of the reverse primer for RSV A Each tube ... Virology Journal 2009, 6:133 Background Respiratory syncytial virus (RSV) causes major outbreaks of acute respiratory infections (ARIs) in children and adults Infections...

Ngày tải lên: 12/08/2014, 04:20

... caused by respiratory syncytial virus in Croatia in 2006 and 2007 by viral subtype and age Bronchiolitis and pneumonia (No.) caused by respiratory syncytial virus in Croatia in 2006 and 2007 by ... Biosystems) The N gene of RSV A and of RSV B were targeted with primers and probes (as listed below), according to van Elden et al [19], with minor modifications of the reverse primer for RSV A Each tube ... Virology Journal 2009, 6:133 Background Respiratory syncytial virus (RSV) causes major outbreaks of acute respiratory infections (ARIs) in children and adults Infections...

Ngày tải lên: 12/08/2014, 04:20

... finger motif of RSV and other pneumoviruses Numerous methods of inactivation of respiratory syncytial virus have been attempted in the quest for a safe and efficient RSV vaccine Each one of them, ... elongation factor of respiratory syncytial virus, a nonsegmented negative-strand RNA virus Proc Natl Acad Sci USA 1996, 93(1):81-5 Hardy RW, Wertz GW: The product of the respiratory syncytial virus M2 ... Gupta RK, Siber GR: Stabilization of respiratory syncytial virus (RSV) against thermal inactivation and freeze-thaw cycles for development and control of RSV vaccines and immune globulin Vaccine 1996,...

Ngày tải lên: 12/08/2014, 04:21

... eastern part of India is of great significance from the perspective of changing scenario of HBV epidemiology with presence of three distinct genotypes of HBV and four distinct subgenotypes of genotype ... on subgenotypes of genotype A [67], there is a lack of data on the distribution of subgenotypes of HBV genotypes A and D in northern, western and southern parts of India Most of the available ... basis of homology between the viral sequences of the members of same family [60] Previous studies among the primitive tribes of the Andaman and Nicobar islands have shown high endemicity of HBV...

Ngày tải lên: 12/08/2014, 04:21

... Munich University of Technology, Department of Pediatrics, Munich, Germany; Bernard Guillois, Laboratory of Human and Molecular Virology, Caen, France; E Farri-Kostopoulou, St Andrew Hospital, ... Smout RJ: Effect of prematurity on respiratory syncytial virus hospital resource use and outcomes J Pediatrics 2003, 143(5 Suppl):S133-141 Sampalis JS: Morbidity and mortality after RSV- associated ... 2003, 143:S150-S156 IMpact -RSV Study Group: Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk...

Ngày tải lên: 12/08/2014, 14:20

... course of RSV RNA detection by real-time PCR and the presence of replicative virus by plaque assay in the upper (nasal wash) and lower respiratory tract (BAL and whole lung) of RSV infected mice and ... subset of neonates and children with RSV lower respiratory tract infection [8-10] In those studies, RSV RNA was also found in the blood of a small percentage of children with no evidence of RSV ... infection, and the association between the detection of RSV in the blood and parameters of disease severity was inconclusive On the other hand, the detection of RSV RNA in the serum of a 2-month...

Ngày tải lên: 12/08/2014, 11:22

... SS, Collins PL: Contribution of the respiratory syncytial virus G glycoprotein and its secreted and membrane-bound forms to virus replication in vitro and in vivo Virology 2001, 289:283-296 Techaarpornkul ... development of clinical candidates, such as ch101F, for next generation antibody-based prophylaxis and therapy for HRSV infections Abbreviations HRSV Human respiratory syncytial virus F protein ... sitedirected mutagenesis of the HRSV F protein AD and RS participated in the design, oversight of the conduct of the experiments, and interpretation of the results All authors have read and approved the...

Ngày tải lên: 18/06/2014, 18:20

... hepatitis virus, Sendai virus, pneumonia virus of mice, reo-3 virus, mouse encephalitis virus (GD-7), mouse rotavirus (EDIM), minute virus of mice, and Mycoplasma pulmonis; screening for pinworm and ... after RSV inoculation Figure Comparison of RSV loads measured by PCR in lung supernatants of BALB/c and C57BL/6 mice Comparison of RSV loads measured by PCR in lung supernatants of BALB/c and C57BL/6 ... Virology Journal 2005, 2:46 Background Human respiratory syncytial virus (RSV) is classified in the genus Pneumovirus, subfamily Pneumovirinae, family Paramixoviridae; and is a major cause of...

Ngày tải lên: 19/06/2014, 08:20