vibrational spectroscopy in bioprocess monitoring

... detected an increasing NAD(P)H autofluorescence representing an intracellular inadequate oxygen supply Both changes are accompanied by increasing markers of liver cell injury Future therapeutic interventions ... detected in the same animal (p < 0.005; r2 = 0.94), as depicted in Figure Hepatic tissue injury Serum alanine aminotransferase (ALT) and serum aspartate aminotransferase (AST) levels are summarized in ... groups in this study, the differences in the backscattered light spectra only represent differences in the HbsO2 In the past, we have shown that bilateral hindlimb I/R results in a systemic inflammation...

Ngày tải lên: 13/08/2014, 13:20

... business systems technology, and the Internet, in the area of real-time business, the existing time delays in controls checking, information integrity verification, and the backwardly looking ... published in his second successful book, Managing the Audit Function The book was featured in the business section of the Sunday New York Times in August 2002 and translated into Chinese in 2005 In ... by using continuous monitoring (CCM and CCM-T) and continuous auditing According to a January 2009 Gartner report, despite the benefits of CM, too little attention has been placed by chief financial...

Ngày tải lên: 15/03/2014, 20:20

... substantially increased, as IR difference and RR spectroscopy solely probe the vibrational modes reflecting a reaction of the protein and originating from its active site, respectively An additional increase ... [28] With increasing field strength, protein reorientation is increasingly restricted, due to an electric field-dependent increase in the activation barrier for the transition SERR and SEIRA spectroscopy ... iron, leading to a coordination equilibrium between a five-coordinated and a six-coordinated species, in which this axial coordination site remains vacant or is occupied by a histidine (His33...

Ngày tải lên: 22/03/2014, 16:20

... MD studies explained the lower jL as a result of lattice distortions and weaker interatomic interactions among host atoms due to filling atoms.14 Using neutron spectroscopy and ab initio calculations, ... viewpoints have been proposed The concept of localized rattlers8 for the role of guest atoms is supported by a number of studies including Raman spectroscopy, 9 inelastic neutron scattering, heat ... skutterudites.17 In this work, we investigate the details of the interactions between the filled elements and the phonons in single and multiple filled skutterudites These studies allow determination of...

Ngày tải lên: 06/05/2014, 08:53

... Translational Medicine 2009, 7:99 http://www.translational-medicine.com/content/7/1/99 Figure FCS instrumentation for use in living cells FCS instrumentation for use in living cells On the left ... in FCS to study protein-protein interactions, attachment and many more (Figure 1) Fluorescence Correlation Spectroscopy (FCS) uses statistical deviations of the fluctuations in fluorescence in ... Fluorescence Spectroscopy: An emerging excellent diagnostic tool in Medical Sciences Applied Spectroscopy Reviews J (In press) virus particles by analysis of tryptophan emission spectra during infection...

Ngày tải lên: 18/06/2014, 15:20

... have since occurred Since Sirajganj was a low-performing area in terms of indicators on health and family-planning, the present study was intended to evaluate whether an in- built monitoring sys- ... training were instrumental The FWAs almost universally maintained the recommended protocol for administering injectables even after the withdrawal of the interventions The high coverage of routine ... recommended protocol during administering injectable contraceptive through an observation checklist Thirty-four meetings in 1995 and 36 meetings in 1996 were observed All types of meetings were regularly...

Ngày tải lên: 18/06/2014, 17:20

... This index is expressed in %/s From the TCD data, we also calculated the Gosling's pulsatility index (PI) of the MCA in baseline conditions and in correspondence of the maximum CBFV increase during ... made by taking into account what happens during the BH phase Figure reports an example of the changes occurring in the O2Hb (red line) and CO2Hb (blue line) concentrations during BH of a single healthy ... has a greater correlation with the increase in CBFV; this is not surprising since O2Hb concentration is predominant in the cerebral cortex Approximating the increase of the regional cerebral blood...

Ngày tải lên: 19/06/2014, 10:20

... exhibit interference phenomena including AutlerTownes splitting and gain without population inversion when driven simultaneously by two optical fields In this case, researchers are indulged in quantum ... experiments in the near future Competing interests The authors declare that they have no competing interests 11 Authors’ contributions JJL finished the main work of this article, including deducing the ... molecules in solution form may be distorted in mess, but one can extend these molecules into linear form by applying electromagnetic field or fluid force [31] In addition, the longitudinal vibrational...

Ngày tải lên: 22/06/2014, 00:20

... distributions In spite of using Gaussian fitting procedure, it makes basic difficulties in positioning signals in DLTS spectra and also in differing between the p- and sstates As noticed in Fig 3b, ... electron binding energies, given in Table 1, also need to place the ‘‘Cape’’ into the right position by using capture cross sections of the p-electrons in the range as obtained by experiments in Ref ... literature data [3] For increasing values, this quantity did not in uence the result until reaching the ns range We estimate the precision in the determination of average electron binding energies from...

Ngày tải lên: 22/06/2014, 01:20

... Microwave  Infrared (IR) The History of Infrared and Raman Spectroscopy  Infrared (IR) Spectroscopy: – First real IR spectra measured by Abney and Festing in 1880’s – Technique made into a routine ... occurs between vibrational groups sharing an atom – In bending vibrations, the strongest coupling occurs between groups sharing a common bond – Coupling between stretching and bending modes can ... recent innovations in instrument design, accesses a region of crystalline phonon bands P F Taday and D A Newnham, Spectroscopy Europe, , www.spectroscopyeurope.com G Winnewisser, Vibrational Spectroscopy...

Ngày tải lên: 27/06/2014, 01:20

... implemented by incorporating coated fibres into a microsyringe [2] The metal rod, which serves as the piston in a microsyringe, is replaced with stainless steel microtubing with an inside diameter ... 0.6cm/min 2.0cm/min 7.1cm/min 67.8cm/min n-hexane Fig 1.15 Relationship between face velocity and sampling rate (Z ¼ 0.45 cm) achieved either by increasing the volume of the coating or by changing ... ingredients to interest a broad audience of scientists involved in environmental monitoring Finally, I would like to thank all the contributors for their time and efforts in preparing this excellent...

Ngày tải lên: 28/06/2014, 00:20

... caused by to a the increase of mineral component agrees with data from Paul (1988) for soil contamination in silage and Windham et al (1991) for increasing ash concentration in forage, esophageal ... heating and drying on yeild of fiber and lignin in forages J Assoc Off Anal Chem 48, 785-790 Williams PC (1975) Applications of near-infrared reflectance spectroscopy to analysis of cereal grains ... our objectives were i) to determine the changes in spectra during decomposition process, ii) to evaluate the potential of NIRS for determining litter chemistry during decomposition, and iii) to...

Ngày tải lên: 08/08/2014, 23:22

... stability, or during changes in intravascular volume in the absence of significant variation in vascular tone, and so may be helpful in guiding volume loading (for example, during ‘early goal-directed ... experiment that shows that, in patients undergoing coronary artery bypass grafting, variations in ABP in response to a stepwise change in noradrenaline lead to parallel changes in CO measured by the ... the reflected wave and the incident wave in the frequency domain) can be increased only marginally by intense vasoconstriction [13] Studies looking at the differences in CO when the FTV was connected...

Ngày tải lên: 13/08/2014, 20:21

... Acquiring and collecting data in an indirect manner (non-intrusively) without Chapter Introduction Figure 1.1: Components of a data-driven tool condition monitoring system causing machinery downtime ... such as grinding [41], milling [33, 42, 43, 44, 45],drilling Chapter Introduction [37], turning [46, 47] The cutting tool wear monitoring and prediction of useful life were modeled using hidden ... as the inputs to predict the continuous wearing metric of the cutter [5, 6, 48] In this thesis, tool wear monitoring in a CNC-milling machine is used as an illustrative example for continuous...

Ngày tải lên: 08/09/2015, 18:19

... Characterization by the binary phase diagram 56 4.3.1.1 Melting point phase diagram of 4-hydroxy-2pyrrolidone 57 4.3.1.2 Melting point phase diagram of N-methylephedrine 65 4.3.1.3 Melting point phase diagram ... Figure 4.7 Determination of temperatures of fusion (Tf) for N-methylephedrine 65 Figure 4.8 Binary phase diagram (melting point diagram) of Nmethylephedrine 70 Figure 4.9 Determination of temperatures ... population balance modelling (Randolph and Larson, 1988) The newly developed on-line monitoring and controlling techniques provide good tools to facilitate this kind of investigation (Barrett and...

Ngày tải lên: 14/09/2015, 18:18

... monitoring on specific forest type or a threatened wildlife species By using this source of knowledge, we can save our time in finding relationship among living things or non-living things in local ... or product harvesting experiences This paper tries to explore how local people define their forest by using indicators species and potential use of these findings integrated in forest allocation ... between local interview data and forest survey data on list of potential indicator species In order to explore possibility of using local knowledge integrated in forest monitoring, we compare...

Ngày tải lên: 12/08/2016, 22:03

... Within the Section, several Task Groups are playing the role of workhorses A synopsis of monitoring methods and devices was missing from the beginning The interest in obtaining up-to-date information ... on-line measuring equipment Depending on the site of installation, one discriminates further between in situ, which means built -in, and ex situ, which can mean in a bypass or in an exit line; in ... out pioneering work in several fields From the beginning, he stressed the necessity of interdisciplinary and international cooperation He especially promoted cooperation between engineering and...

Ngày tải lên: 03/10/2016, 12:09

... a solid cylindrical tube of elastic continuous material, as shown in Figure 6c Following Balandin et al [16] the viral protein coat has an inner radius "a" and outer radius "b" The inner and outer ... is a linear combination of Bessel functions of the 1st and 2nd kinds, and the angular dependence is sinusoidal being proportional to sin(nθ) and cos(nθ) where n is an integer, n = [0,∞] Since ... Raman scattering profile is shown in Figure In this figure we have only included the axial modes since they should resonate with little damping We have included a Gaussian broadening of cm-1,...

Ngày tải lên: 20/06/2014, 02:20

... metatarsophalangeal joint he was unaware that gout could occur in his wrist Typical presentation includes sudden onset of intense pain, redness and swelling of the joint Examination will reveal ... appearance of gout in MR imaging is variable Joint effusion and para-articular edema may be present in an inflamed joint Tophaceous deposits will appear low to intermediate signal intensity on T1weighted ... aspirin, up to g/day has the potential to increase uric acid retention [11,13] The combination of low-dose aspirin and diuretics compounds this effect [13] Clinicians should inquire regarding...

Ngày tải lên: 25/10/2012, 10:06

... multifocal chorioretinitis can help establish an early diagnosis of the disease while serologic testing is pending Therefore, an ocular examination, including ophthalmoscopy and FA in selected cases, ... Int J Med Sci 2009, 115 vicides…) and personal protection against mosquito bites (repellants, window screens, protective clothing,…) Vaccination, a long term solution, is still in the ... the routine evaluation of patients with clinically suspected WNV infection References Hayes EB, Gubler DJ West Nile virus: epidemiology and clinical features of an emerging epidemic in the United...

Ngày tải lên: 03/11/2012, 11:17