veterinary pharmacovigilance the uk experience

... 30 The role of veterinary pharmacovigilance in risk analysis and the influence of risk perception on veterinary pharmacovigilance H.P.A Illing 31 The role of quality assurance in veterinary pharmacovigilance ... tragedy led to the establishment of the regulation of human and veterinary medicines in the UK with the introduction of the Medicines Act 1968 Similarly, a disaster in the USA where the solvent ... within the EU and in the rest of the world where the product is authorised PSURs are timed from the so-called EU birth date, i.e from the date when the product was first authorised in the EU The...

Ngày tải lên: 06/03/2014, 16:20

... containing part of the enhancer region of the rice actin promoter at the 3’ end of the inserted DNA in the inverse direction of the cp4 epsps cassettes RT-PCR analyses were conducted across the 3’ junction ... initiate in either one of the two promoters of the NK603 insert and proceed through the NOS 3’ polyadenylation sequence and continue into the corn genomic DNA flanking the 3’ end of the insert This ... within their diets because of their extremely rapid growth Within the poultry studies conducted by Monsanto, the power of the test is sufficient to detect 2-4% differences in the mean of the test...

Ngày tải lên: 01/07/2014, 18:01

... feature of these antimicrobial factors is that their activity is increased by low ionic strength [6-9] Lowering the ASL salt concentration might therefore increase the efficacy of the innate ... β defensins, and the cathelicidin LL-37 [1-4] The antibacterial activity of most of these innate immune mediators is salt-sensitive; an increase in salt concentration inhibits their activity [5] ... throughout the study The most common symptom reported was stuffy nose after xylitol exposure, which occurred in five (50%) subjects after the 10 ml dose (Table 4) The mean VAS score among the five...

Ngày tải lên: 12/08/2014, 18:21

... accounted for 39.2% (58/148) of the total number of events (Table 5) The incidence of serious bleeding events was highest during the first day of therapy and decreased thereafter for all drotrecogin ... complications associated with the use of drotrecogin alfa (activated) The primary limitation of these analyses was the lack of placebo treatment groups for five of the seven studies reported, and ... Acknowledgements The authors are very grateful to the clinical staff at the Vanderbilt Coordinating Center; to all of the investigators, study coordinators, and pharmacists who participated in the clinical...

Ngày tải lên: 12/08/2014, 19:22

... construction Due to the foreshore erosion, the sand near the toe was taken away After that the toe and the outer part of the dikes could be collapsed Further more the water depth at the toe of the dikes ... water via the dike crest On the other hand the inner side of the dikes is not well protected Therefore the damages of inner side usually happen As understanding from the current situation, the damages ... than the first However, these dikes must and will be reinforced when the water reaches them; otherwise they will not long lasting The distance between the dikes varies roughly 200 meters The land...

Ngày tải lên: 03/10/2014, 13:14

... θ)f (θ)dθ]−1 is the normalizing constant and L(D | θ) is the likelihood of the observed data given the parameter θ Based on the posterior distribution, the updated estimate of the parameter θ ... the vectorization technique is performed upon the sub-matrices to estimate the interval bounds for the unknown stiffness parameters The major difficulty associated with interval computation is the ... developed and the characteristics of the available information in a particular case provide the basis for the selection of the most appropriate approach from this variety In this thesis, imprecise...

Ngày tải lên: 10/09/2015, 08:39

... in the system of therapeutics according to the traditional Chinese method (The Statutes of the Republic of Singapore, 2005) The legislations governing the control of CPM in Singapore includes the ... knowledge, this is thus far the only method that can provide such comprehensive screening of the PDE-5 inhibitors and their related analogues The final part of the project involved the structural elucidation ... herbal product in 1990 The mother experienced increased hair growth on her head, forehead and public area At birth, the male child had thick hair in the pubic region, and on the forehead, along...

Ngày tải lên: 13/10/2015, 15:55

... adopted a national perspective, the goal of which was to assess the progress of the AHRQ initiative and the activities of other federal agencies in the context of the larger U.S patient safety ... be critical to synthesize them in ways that make the information accessible to various end users These include the scientific community, which will use the results for updating the body of evidence ... is being tested These users then can help in future dissemination efforts as early adopters of the system With respect to the content of the data to be reported, the work that the patient safety...

Ngày tải lên: 18/02/2014, 01:20

... engaged As the innovation matures, adoption then levels off After five years of the patient safety initiative, the United States stands at the threshold of the upward moving portion of the curve ... by coordinating the work of the Coordinating Center and the Resource Center, and integrating them whenever possible, including the joint conduct of the annual conferences for the two groups of ... organizations; the 100,000 Lives (now the Million Lives) Campaign led by the Institute for Healthcare Improvement (IHI) with the support of the American Medical Association (AMA), the Centers for...

Ngày tải lên: 15/03/2014, 22:20

... 87.5% of the cases As independent factors the distance between the isocenter and the initial tumor margin (the higher the distance the lower the dose, p = 0.0004) as well as the geometry of the initial ... direction) [23,24] Therefore, the PTV in external beam liver radiotherapy exceeds the CTV substantially [3] In CT-guided brachytherapy the catheters are positioned and fixed inside the tumor Hence, ... after positioning of the brachytherapy catheters in the tumor Depending on tumor geometry and lesion size, a median of catheters was used in our patients (range: 20 catheters) The 3D CT data set...

Ngày tải lên: 09/08/2014, 08:23

... immunostimulants on the basis of their ability to promote effective humoral and cell-mediated immune responses This is further evident in another study in which we assessed their adjuvanticity ... described, the target cells were labeled at 37°C with 150 μCi of sodium 51Cr for hr, washed three times in PBS, and then resuspended in RPMI/10% FBS [28] The labeled target cells were then dispensed ... appropriate target cells seeded in 96-well plates The total volume of the reaction was 200 μL/well The plates were incubated at 37°C for h, after which they were centrifuged, and 30 μL of supernatant...

Ngày tải lên: 11/08/2014, 10:23

Ngày tải lên: 11/08/2014, 10:23

Ngày tải lên: 23/09/2012, 16:00

... transmit back into the EMCC record the times of (1) departure from the station, (2) arrival on-scene, (3) departure from the scene, and (4) arrival at the hospital or LEMC In addition, there are fields ... recording the same time data in the ambulance records We registered the frequencies of completion of these Page of 11 patient encounter times, both in the electronic EMCC records and in the ambulance ... usage, the flow of individual patients through the EMS system must be tracked, as one ambulance crew may be the first to arrive on scene, while another crew may eventually transfer the patient to the...

Ngày tải lên: 25/10/2012, 09:56

... 134 aged This is particularly true with regards to T gondii, where the consequences of infection can be very severe, while the risk of living with one’s beloved cat is practically nill References ... CA, Angulo FJ, Rooney JA Animal-associated opportunistic infections among persons infected with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence ... 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163 http://www.medsci.org...

Ngày tải lên: 03/11/2012, 11:06

... to the others For example, the flow from University to Industry and vice versa Therefore, these flows become the main factor in the individual model and are considered as the third level The ... structural The former is the familiar contextual dependence of elements on other elements in performing their function, whereas the later is the dependence of the priority of elements on the priority ... from the top with the goal having the greatest influence of importance The AHP model formulation process starts both from bottom (the alternatives) and from the top (the objective, goal) or the...

Ngày tải lên: 23/04/2013, 10:29

... in Colorado It was one of the most energetic vacations I’ve ever had Every day, we walked for five hours, then we set up camp At the campsite, we read for a few hours, then made dinner over a campfire ... hiking in Colorado It was _ of the most energetic _ I’ve ever had Every day, we walked for _ hours, then we set _ camp At the campsite, we read for a _ hours, then _ dinner over a campfire ... Which activities you want to try out? ASSESS THE LISTENING TEST Assess the Listening test in your handout • What are the strengths of this test? • What are the weaknesses? • How would you design a...

Ngày tải lên: 18/08/2013, 17:10

... 116oE It is bounded to the northwest by the province of West Kalimantan, to the northeast by East Kalimantan, to the southeast by South Kalimantan, and to the southwest by the Java Sea (Fig 1) ... Technology, Vol 6, No.2, 2008 The average water flow during the rainy season in the Kahayan River is 400 m3/s and that in the Rungan is 165 m3/s During the dry season, the respective flows are 55 ... people living in the sampling watershed However, at the same time, levels of contaminants in fish are of considerable interest because of the potential effects on the fish themselves or the organisms...

Ngày tải lên: 05/09/2013, 09:38

... with river water before the sample was placed and then the bottle was tightly covered so that air would not enter The glass bottle containing the sample was kept at 4˚C until the time of concentration ... measured MPP and its oxides in river water On the basis of the metabolic profile and from the knowledge of environmental exposure routes, we further discussed the possible acute toxicity from exposure ... mentioned previously, the existence of MPP and its oxides in river water was studied From the results of the GC/MS analysis for the period April to August, a peak was observed on the chromatogram...

Ngày tải lên: 05/09/2013, 10:15