vascular endothelial growth factor and tumour associated macrophages

... tumor necrosis factor- α, vascular endothelial growth factor1 65 and SU1498 on ADAM15 expression (a) Effect of tumor necrosis factor expression (TNF)-α and vascular endothelial growth factor (VEGF)165 ... 661 NM001101 ADAM, a disintegrin and metalloproteinase; VEGFR, vascular endothelial growth factor receptor; vWF, von Willebrand factor for the primers and probe and the absence of DNA polymorphisms ... ADAM15, vascular endothelial growth factor receptor (VEGFR)-2 and von Willebrand factor (vWF) (a-d) Rheumatoid (vWF) arthritis (RA) synovial fibroblasts (SFs) and (e-h) human umbilical vein endothelial...

Ngày tải lên: 09/08/2014, 07:20

... induced and outweigh the inhibitors, resulting in the initiation of angiogenesis [4] Among the angiogenesis inducers, vascular endothelial growth factor (VEGF) and basic fibroblast growth factor ... Synergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo Circulation 1995, 92(suppl):S365-S371 Kalluri R, Sukhatme VP: Fibrosis and angiogenesis ... of the transcription factor hypoxia inducible factor [31] In addition, a variety of cytokines (e.g interleukin-1, transforming growth factor beta and platelet-derived growth factor) known to be...

Ngày tải lên: 09/08/2014, 06:22

... of angiogenic factors such as VEGF, fibroblast growth factor (FGF) and platelet-derived growth factor are secreted from neuronal cells, astrocytes and inflammatory cells, including macrophages that ... neutralizing IgG and immunotherapy against VEGFRs are undergoing clinical trials Table Activities of vascular endothelial growth factor (VEGF) family members PlGF, placenta growth factor; T.F svVEGF, ... strong interaction between vascular endothelial cells and astrocytes, and the tight junctions of vascular endothelial cells (ECs) in the BBB are well organized with claudins and ZOproteins through...

Ngày tải lên: 18/02/2014, 11:20

... Vascular- specific growth factors and blood vessel formation Nature 407, 242–248 Ó FEBS 2004 Neufeld, G., Cohen, T., Gengrinovitch, S & Poltorak, Z (1999) Vascular endothelial growth factor (VEGF) and its ... Post-transcriptional regulation of vascular endothelial growth factor by hypoxia J Biol Chem 271, 2746–2753 17 Shih, S.-C & Claffey, K.P (1999) Regulation of human vascular endothelial growth factor mRNA stability ... of vascular endothelial growth factor mRNA by HuR J Biol Chem 277, 13635–13640 19 Miller, D.L., Dibbens, J.A., Damert, A., Risau, W., Vadas, M.A & Goodall, G.J (1998) The vascular endothelial growth...

Ngày tải lên: 19/02/2014, 12:20

... for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation J Biol Chem 275, 5096–5103 32 Kroll, J & Waltenberger, J (1997) The vascular endothelial ... cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation J Cell Biochem ... King, G.L (1996) Characterization of vascular endothelial growth factor s effect on the activation of protein kinase C, its isoforms, and endothelial cell growth J Clin Invest 98, 2018–2026 29...

Ngày tải lên: 19/02/2014, 16:20

... Hypoxia-induced angiogenesis and vascular endothelial growth factor secretion in human melanoma Br J Cancer 1998, 77:897-902 37 Straume O, Akslen LA: Expression of vascular endothelial growth factor, its receptors ... lumbar, and sacral bones), skull (maxilla, mandible, and cranium), thorax (sternum, ribs, and scapula), pelvis (ilium, ischium, and pubis), foreleg (humerus and radius) and hindleg (tibia and femur) ... Subsequent invasion and growth of metastatic cells at bony sites appear to be facilitated by TGFb [4] and hematopoietic growth factors [5,6], tumor -associated angiogenesis [7,8] and bone remodeling...

Ngày tải lên: 18/06/2014, 22:20

Ngày tải lên: 19/06/2014, 22:20

... sclerosis; VEGF-A, vascular endothelial growth factor- A; CCL2, chemokine ligand-2; PBMCs, peripheral blood mononuclear cells and differentiation of VEGF receptor (VEGFR1), VEGFR2 and chemokine receptor ... of VEGF-A and CCL2 were normalized to expression of endogenous control b-actin ALS, amyotrophic lateral sclerosis; VEGF-A, vascular endothelial growth factor- A; CCL2, chemokine ligand-2; PBMCs, ... sclerosis; VEGF-A, vascular endothelial growth factor- A; CCL2, chemokine ligand-2; PBMCs, peripheral blood mononuclear cells Conclusion Although it can not be concluded that increased VEGFA and CCL2 expression...

Ngày tải lên: 19/06/2014, 22:20

... but not human placenta-derived growth factor, platelet-derived growth factor, or transforming growth factor Inter- and intra-assay variances for VEGF, sVEGFR-1, and sVCAM-1 were lower than 10% ... Matucci-Cerinic M: Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the ... [VEGF] and [sVEGFR-1] did not differ between patients with SSc and controls Several factors contribute to VEGF production, including hypoxic conditions and stimulation by transforming growth factor, ...

Ngày tải lên: 09/08/2014, 01:23

... of vascular endothelial growth factor in the regulation of angiogenesis Kidney Int 1999, 56:794-814 Neufeld G, Cohen T, Gengrinovitch S, Poltorak Z: Vascular endothelial growth factor (VEGF) and ... mean ± standard error of the mean; n = (Con) and n = (OA) * p < 0.05 Con, control; OA, osteoarthritis; VEGF, vascular endothelial growth factor Statistics All data are shown as mean ± standard ... results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor Am J Pathol 2003, 163:1321-1327 Gruber BL, Marchese MJ, Kew R: Angiogenic factors...

Ngày tải lên: 09/08/2014, 08:23

... PC12 cells Comparison of the effects of nerve growth factor and epidermal growth factor Biochem J 1992, 288 ( Pt 2):351-355 Publish with Bio Med Central and every scientist can read your work free ... Donoghue MJ, Fan SY, Kim H, Stewart WB, Madri JA, Ment LR: Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system J Biol Chem 2002, 277:11410-11415 ... 277:11410-11415 Gerber HP, McMurtrey A, Kowalski J, Yan M, Keyt BA, Dixit V, Ferrara N: Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'kinase/Akt signal...

Ngày tải lên: 11/08/2014, 08:20

... growth factor and vascular endothelial growth factor in sera of cancer patients Br J Cancer 1997, 76:238-43 27 Kondo S, Asano M, Suzuki H: Significance of vascular endothelial growth factor /vascular ... endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo Circulation 1995, 92:II365-71 25 Salven P, Mänpää H, Orpana A, Alitalo K, Joensuu H: Serum vascular endothelial growth ... sufficient perfusion and oxygen supply The present study focuses on the relevant mediators of angiogenesis which are vascular endothelial growth factor (VEGF) and basic growth factor (bFGF) In angiogenesis,...

Ngày tải lên: 11/08/2014, 20:20

... probe and primers name, symbol and ID Gene Symbol Assay ID Vascular endothelial growth factor A Vascular endothelial growth factor B Vegfa Vegfb Placenta growth factor Pgf Rn00585926_m1 Vascular endothelial ... JH: Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF) J Cell Mol Med 2005, 9(4):777-94 Wirzenius M, et al: Distinct vascular endothelial growth factor signals ... Purification and characterization of a naturally occurring vascular endothelial growth factor. placenta growth factor heterodimer J Biol Chem 1995, 270(13):7717-23 Eriksson A, et al: Placenta growth factor- 1...

Ngày tải lên: 12/08/2014, 13:22

... Van de WL, Dvorak HF, Senger DR: Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors Mol Biol Cell 1992, ... Mura AL, Pinto M, Zamboli A, De Vita F, Galizia G: Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of ... H: Real-time RT-PCR quantitative assays and postmortem degradation profiles of erythropoietin, vascular endothelial growth factor and hypoxia-inducible factor alpha mRNA transcripts in forensic...

Ngày tải lên: 12/08/2014, 14:20

... CD, Lynch DA, Flores SC, Voelkel NF: Endothelial cell death and decreased expression of vascular endothelial growth factor and vascular endothelial growth factor receptor in emphysema Am J Respir ... immunoreactive vascular endothelial growth factor and its relation to smoking Metabolism 1998, 47:27-30 Kanazawa H, Asai K, Hirata K, Yoshikawa J: Possible effects of vascular endothelial growth factor in ... rat and human adult lung, and in experimental rat lung fibrosis: light fluorescence and electron microscopy Anat Rec 1999, 254:61-73 Kanazawa H, Asai K, Nomura S: Vascular endothelial growth factor...

Ngày tải lên: 12/08/2014, 15:21

... Herzog Y, Neufeld G: Neuropilin-2 and neuropilin-1 are receptors for the 165-amino acid form of vascular endothelial growth factor (VEGF) and of placenta growth factor- 2, but only neuropilin-2 ... embryogenesis Dvorak HF, Brown LF, Detmar M, Dvorak AM: Vascular permeability factor /vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis Am J Pathol 1995, 146:1029-1039 ... circulating levels of VEGF-A and greater risk of ALS Autiero M, Luttun A, Tjwa M, Carmeliet P: Placental growth factor and its receptor, vascular endothelial growth factor receptor1: novel targets...

Ngày tải lên: 14/08/2014, 14:21

... V, Ariel I, Yagel S: Vascular endothelial growth factor, epidermal growth factor and fibroblast growth factor- 4 and -10 stimulate trophoblast plasminogen activator system and metalloproteinase-9 ... Medium (DMEM) and foetal bovine serum (FBS) were from PAA (Lodz, Poland) Recombinant human vascular endothelial growth factor (rhVEGF-A) and recombinant human fibroblast growth factor (rhFGF4) ... as: Jazwa et al.: Combined vascular endothelial growth factor- A and fibroblast growth factor gene transfer improves wound healing in diabetic mice Genetic Vaccines and Therapy 2010 8:6 ...

Ngày tải lên: 14/08/2014, 19:22

... Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory ... activation and expression of proinflammatory cytochemokines by placenta growth factor Blood 102, 1515–1524 30 Shibuya M (2001) Structure and dual function of vascular endothelial growth factor receptor-1 ... of vascular endothelial growth factor- E J Biol Chem 281, 19578–19587 23 Keyt B, Nguyen H, Berleau L, Duarte C, Park J, Chen H & Ferrara N (1996) Identification of vascular endothelial growth factor...

Ngày tải lên: 23/03/2014, 07:20

... Background: Anti -vascular endothelial growth factor (VEGF) drugs and/ or photodynamic therapy (PDT) constitute current treatments targeting pathological vascular tissues in tumors and age-related ... retina, neuroprotection, Akt, BAX Background Vascular endothelial growth factor (VEGF) was first identified as a soluble factor that promotes tumor neovascularization [1] Targeting VEGF has been ... understanding of its roles in each context is required to establish better therapeutic protocols leading to better prognosis List of abbreviations VEGF, vascular endothelial growth factor; VEGFR1, vascular...

Ngày tải lên: 19/06/2014, 22:20