utility of adenovirus based vectors for multiple cancer vaccine approaches

... recognition performance (using a significance test for a binomial random variable), as compared with the performance of the triphone recognisers However, the performance of the syllable-model and of the ... different numbers of syllables As Table illustrates, the word structure of CGN was highly similar to that of TIMIT The third column of Table illustrates the proportions of the different types of syllable ... Belgium All of the data are transcribed orthographically, lemmatised (i.e., grouped into categories of related word forms identified by a headword), and enriched with part -of- speech information,...

Ngày tải lên: 22/06/2014, 19:20

... of a mutation in one copy of the SH2D1A gene in other kindreds should be considered at-risk of symptomatic XLP, and hence may need to be monitored for the development of phenotypic features of ... patients for genetic counseling before testing for these disorders It is very important to discuss the potential advantages and disadvantages of testing with patients before sending blood samples for ... testing of minors is the subject of multiple international guidelines and position papers Recent systematic reviews of these guidelines [58,59] suggest that in the case of carrier testing of minors,...

Ngày tải lên: 08/08/2014, 21:20

... loading ≤ ug of total peptides Therefore we concluded that the remaining 95% of each sample was equivalent to 10-20 μg of protein for the purposes of shotgun MS/MS analysis We next employed offline ... Hanash SM, Omenn GS, States DJ: Identification of Novel Alternative Splice Isoforms of Circulating Proteins in a Mouse Model of Human Pancreatic Cancer Cancer Research 2009, 69(1):300-309 22 Rudney ... could be used for oral cancer detection in this easily collected fluid [6,23] Finally, the PerioPaper strips could provide the foundation for point -of- care clinical devices for oral cancer diagnostics,...

Ngày tải lên: 13/08/2014, 13:20

Ngày tải lên: 17/10/2013, 19:15

... the utility of these approximations of the SPADE-like context-free features The performance of the resulting “Full” finite-state system is not statistically significantly different from that of ... percentages from to 100 For a string of length k, at position i, we round i/k to two decimal places and provide a value of for the corresponding quantized position feature and for the other position ... algorithm, since this forms the basis of our features The SPADE features are based on productions extracted from full syntactic parses of the given sentence The primary feature for a discourse boundary...

Ngày tải lên: 08/03/2014, 02:21

... Therefore, objects can be described by different cues These include model -based approaches (e.g., [11, 12, 124]), shape -based approaches (e.g., ), and appearance -based models Model -based approaches ... for uniform regions and regions with smooth transitions Region based detectors regard local blobs of uniform brightness as the most salient aspects of an image and are therefore more suited for ... Compute eigenvectors uj and eigenvalues λj of G 5: Determine eigenvalues of C: ˘ λj = λj 6: Determine eigenvectors of C: ˆu X˘ j uj = √ n − λj U = [u1 , , un−1 ] For the definition of the Gram...

Ngày tải lên: 24/04/2014, 13:47

... increase the risk of granulosa cell tumor of the ovary Consent Written informed consent was obtained from the patient for publication of this case report and accompanying images A copy of the written ... and feasibility of tamoxifen for prevention of breast cancer Br J Cancer 1989, 60(1):126-31 Fisher B, Costantino JP, Redmond CK, Fisher ER, Wickerham DL, Cronin WM: Endometrial cancer in tamoxifen-treated ... for Research on Cancer, Lyon, France 1996, 66:253-365 11 Swerdlow AJ, Jones ME: Tamoxifen treatment for breast cancer and risk of endometrial cancer: a case-control study J Natl Cancer Inst 2005,...

Ngày tải lên: 09/08/2014, 03:22

... For example, for an IS composed of two ORFs, ISsaga will extract the nucleotide sequence starting from the coordinates of the beginning of the first ORF to the coordinates of the end of the second ... introduced a number of rules that operate automatically to remove many of the major annotation ambiguities encountered due to the diversity and complexity of ISs (for example, the presence of more than ... Exploitation of ISsaga Genome context One useful feature of ISsaga is that it supplies the genome context (that is, flanking genes) for each annotated Page of IS, allowing identification of IS-induced...

Ngày tải lên: 09/08/2014, 22:24

... informed consent was obtained from the patient for publication of this case report and any accompanying images A copy of the written consent is available for review by the Editor-in-Chief of ... BCG has proved to be an effective form of treatment for some stages of bladder Figure Computed tomography scan showing 43 mm abscess affecting the pancreatic head cancer [4] There are specific risks ... Surgical exploration and drainage were performed and cultures of the purulent material were positive for M bovis Urine and blood cultures were negative for acidfast bacilli stains Antitubercular...

Ngày tải lên: 11/08/2014, 17:21

... found for delta SOFA (range = 0.51 to 0.828) P values of HL-statistics ranged from 0.33 to 0.95 for total max SOFA and were all beneath 0.05, indicating poor fit, for delta SOFA and mean SOFA Performance ... with each one of total max SOFA, delta SOFA and admission SOFA [4] Overall performance and discrimination were both improved by the addition of total max SOFA and of the delta SOFA, especially ... individual components of SOFA (Failure-Non failure), = Sequences of categorised SOFA scores (HighMedium-Low), = SOFA trend over days (-1 if SOFA is decreased, if SOFA is unchanged, if SOFA is increased),...

Ngày tải lên: 13/08/2014, 11:23

... evaluate the level of GFP expression above the threshold level of autofluorescence of non-transfected control cells For each assay three independent transfections were performed and mean fluorescence ... 50°C for 15 min, initial denaturation at 95°C for min, 45 cycles of denaturation at 95°C for 15 sec and annealing with extension at 60°C for 30 sec Fluorescence data were collected at the end of ... used from a range of 100 to 600 nM for optimum concentration CT values were recorded each time 200 nM of forward and reverse primer with 100 nM of probe were found to be optimal for one step qRT-PCR...

Ngày tải lên: 14/08/2014, 19:22

... to be valid for other types of tumors For all these, the addition of appropriate cancer- free control materials to the screening panels might help in the identification of truly informative markers ... colorectal cancer J Natl Cancer Inst 2005, 97:1330-1338 Liang G, Wolff EM, Chihara Y, Pan F, Weisenberger D, Laird PW, Jones PA: DNA methylation profile of 1501 loci in bladder cancer shows evidence of ... Ohlsson R, Henikoff S: The epigenetic progenitor origin of human cancer Nat Rev Genet 2006, 7:21-33 Giovannucci E, Ogino S: DNA methylation, field effects, and colorectal cancer J Natl Cancer Inst...

Ngày tải lên: 14/08/2014, 21:20

... stages: Selection of topic and idea generation, organisation of ideas and identification of areas of enquiry; research and information gathering; compilation and analysis of information; publication, ... coordinators for each group… (2) A time of gathering information from various sources including a selection of appropriate information (3) A time of analyzing data gathered (4) A time of presenting ... always” , 36.7% of them said “Yes, often” and 16.7 % of them sometimes felt unwilling As a result of the students’ inadequate awareness of the interest of English speaking, most of students felt...

Ngày tải lên: 30/03/2015, 14:01

... the aid of low concentration of TOAB, small-sized NPs were transferred into toluene, while chloroform and carbon tetrachloride extracted large-sized NPs [91] In spite of such efforts for purification ... step of optimization Figure 3-3 Effects of variations of influential factors on extraction efficiency of Ag NPs (A) Effects of sample pH on zeta potential and extraction efficiency (B) Effect of ... evaluation of the environmental health and safety of NMs [6] The International Office for Standardization (ISO) has also developed and published a number of standardized protocols within the scope of...

Ngày tải lên: 09/09/2015, 08:18

... OPTIMIZATION OF IMAGE BASED METHODS FOR MONITORING CRYSTALLIZATION PROCESSES ZHOU YING (M.Sc., National University of Singapore, B.Eng., Dalian University of Technology, China) A DISSERTATION SUBMITTED FOR ... extraction of information from in-situ images remains a challenging task for several reasons: Chapter Introduction  The in-process video offers a 2-d image of 3-d objects with the consequent loss of ... lab-mates, for their efforts and assistance It is a pleasant experience to work with i them together I would also like to acknowledge the National University of Singapore (NUS) for offering me...

Ngày tải lên: 10/09/2015, 15:51

... electrophoretic mobility of gold nanoparticles with different sizes [16] transport of proteins and selective separation of proteins of different charges [15] In this work, the mobilities of charged species ... concentrations of ferrocenes (Fig 2.3B), as expected for mass transfer limited behaviours The slope of the linear curve presents diffusion coefficient of the ferrocene Diffusion coefficients of FcMeOH ... photochemical controls for specific transport of charged species [11, 12] Yamaguchi et al found that the diffusivities of ferrocenes inside silica-surfactant nanochannels formed within a porous...

Ngày tải lên: 11/09/2015, 09:56

... separate the D, L forms of a racemic mixture of (D/L) [11], and to isolate and to concentrate the L form Martin et al could achieve fivefold difference between the transport rates of D- and L-amino ... platinum-coated layers of a micrometer-thick membrane This has the advantage of achieving high field strengths of about 30 kV m−1 suitable for electrokinetic transport of proteins using very ... point of Lys was 11.0, which was higher than the solution pH of 5.5 At 76 -1.5 V, the receiver side of membrane was of opposite charge to the Lys protein, thus the attractive electrophoretic force...

Ngày tải lên: 11/09/2015, 09:56

... from Prof Ng in collaboration 4.2.2 Inactivation of virus Inactivation of virus was performed by the addition of binary ethyleneimine to the virus suspension to give a final concentration of 0.1 ... 4.6 Plot of AC voltammetry responses (Ip) of the membrane electrodes as a function of square root angular frequency (w1/2) after each step of the sensor preparation procedure for sensing of (A) ... potentially suitable for extreme analysis of a small sample quantity For example, using an array of conical gold nanopores functionalized with thiolated-biotin [16], specific detection of streptavidin...

Ngày tải lên: 11/09/2015, 09:56

... base of ca 25 nm ring thickness is available for the electrodeposition of PB nanotubes Cross-section profile of the membrane electrode after 15 electrodeposition potential cycles reveals growth of ... of the electrochemical conversion between the PB and ES forms and the reversible incorporation of solution K+ ions into/out of the tubes for the PB nanotube sensor To investigate the reason for ... moderate scan rate of 50 mV s-1 154 5.4.3 Performance of PB nanotube K+ selective sensor Fabrication of fast response and stable potassium ion selective sensor are useful for measurement of physiological...

Ngày tải lên: 11/09/2015, 09:57

... application of project management methodologies often relies on accurate estimates of project cost Cost estimation for software project is of particular importance as a large amount of the software ... research on software development effort or cost estimation Papers related to prediction of software size/defects, modeling of software process, or identification of factors correlated with software ... start at the early stage of the software life cycle and continues throughout the life time During the first phases of software life cycle, cost estimation is of necessity for software developing team...

Ngày tải lên: 14/09/2015, 08:40